Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, Jemal A (2024 May-Jun) Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 74(3):229–263. https://doi.org/10.3322/caac.21834

Pandiar D, Krishnan RP (2024) Plausible mechanisms in malignisation of non-habit related chronic nonhealing traumatic ulcers of oral cavity. Indian J Pathol Microbiol 67(3):725–728. https://doi.org/10.4103/ijpm.ijpm_800_23

Article  PubMed  Google Scholar 

Gopalakrishnan K, Kannan B, Pandi C, Pandi A, Ramasubramanian A, Jayaseelan VP et al (2024) Aberrant expression of VASP serves as a potential prognostic biomarker and therapeutic target for oral squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol 138(3):391–402. https://doi.org/10.1016/j.oooo.2024.05.005

Article  PubMed  Google Scholar 

Kannan N, Pandiar D, Subramanian R, Krishnan RP (2024) Helicobacter pylori positive oral squamous cell carcinoma demonstrate higher pathological tumor staging and poorer overall survival. J Stomatol Oral Maxillofac Surg 125(4S):101952. https://doi.org/10.1016/j.jormas.2024.101952

Article  PubMed  Google Scholar 

O’Grady I, O’Sullivan J (2023) Alcohol consumption modulates Candida albicans-induced oral carcinogenesis and progression. J Oral Biosci 65(4):293–304. https://doi.org/10.1016/j.job.2023.10.002

Article  CAS  PubMed  Google Scholar 

Arumugam P, Jayaseelan MSM VP. Pathogenic loss-of-function mutations in LRP1B are associated with poor survival in head and neck cancer patients. J Stomatol Oral Maxillofac Surg 2024 Jul 18:101971. https://doi.org/10.1016/j.jormas.2024.101971

Slieker FJB, Rombout DAA, de Bree R, Van Cann EM (2022) Local recurrence and survival after treatment of oral squamous cell carcinoma of the maxilla: a systematic review and meta-analysis. Oral Surg Oral Med Oral Pathol Oral Radiol 133(6):626–638. https://doi.org/10.1016/j.oooo.2021.10.003

Article  CAS  PubMed  Google Scholar 

Binmadi NO, Basile JR (2011) Perineural invasion in oral squamous cell carcinoma: a discussion of significance and review of the literature. Oral Oncol 47(11):1005–1010. https://doi.org/10.1016/j.oraloncology.2011.08.002

Article  PubMed  Google Scholar 

Binmadi N, Alsharif M, Almazrooa S, Aljohani S, Akeel S, Osailan S et al (2023) Perineural Invasion is a significant prognostic factor in oral squamous cell carcinoma: a systematic review and Meta-analysis. Diagnostics (Basel) 13(21):3339. https://doi.org/10.3390/diagnostics13213339

Article  PubMed  Google Scholar 

Loree TR, Strong EW (1990) Significance of positive margins in oral cavity squamous carcinoma. Am J Surg 160(4):410–414. https://doi.org/10.1016/s0002-9610(05)80555-0

Article  CAS  PubMed  Google Scholar 

Overholt SM, Eicher SA, Wolf P, Weber RS (1996) Prognostic factors affecting outcome in lower gingival carcinoma. Laryngoscope 106(11):1335–1339. https://doi.org/10.1097/00005537-199611000-00006

Article  CAS  PubMed  Google Scholar 

Ash CS, Nason RW, Abdoh AA, Cohen MA (2000) Prognostic implications of mandibular invasion in oral cancer. Head Neck 22(8):794–798. https://doi.org/10.1002/1097-0347(200012)22:8%3C794::aid-hed8%3E3.0.co;2-w

Ebrahimi A, Murali R, Gao K, Elliott MS, Clark JR (2011) The prognostic and staging implications of bone invasion in oral squamous cell carcinoma. Cancer 117(19):4460–4467. https://doi.org/10.1002/cncr.26032

Article  PubMed  Google Scholar 

Ramasubramanian S, Pandiar D, Krishnan RP, Ramalingam K, Bologna-Molina R (2023) Correlation of Bony Invasion with nodal metastasis, pattern of Invasion and Survival in oral squamous cell carcinoma: a retrospective analysis of 122 primary cases from oral Cancer Centre of South India. Cureus 15(8):e42887. https://doi.org/10.7759/cureus.42887

Article  PubMed  PubMed Central  Google Scholar 

Bryne M, Koppang HS, Lilleng R, Kjaerheim A (1992) Malignancy grading of the deep invasive margins of oral squamous cell carcinomas has high prognostic value. J Pathol 166(4):375–381. https://doi.org/10.1002/path.1711660409

Article  CAS  PubMed  Google Scholar 

Camisasca DR, Silami MA, Honorato J, Dias FL, de Faria PA, Lourenço Sde Q (2011) Oral squamous cell carcinoma: clinicopathological features in patients with and without recurrence. ORL J Otorhinolaryngol Relat Spec 73(3):170–176. https://doi.org/10.1159/000328340

Article  PubMed  Google Scholar 

Wang B, Zhang S, Yue K, Wang XD (2013) The recurrence and survival of oral squamous cell carcinoma: a report of 275 cases. Chin J Cancer 32(11):614–618. https://doi.org/10.5732/cjc.012.10219

Article  PubMed  PubMed Central  Google Scholar 

Lindenblatt Rde C, Martinez GL, Silva LE, Faria PS, Camisasca DR, Lourenço Sde Q (2012) Oral squamous cell carcinoma grading systems–analysis of the best survival predictor. J Oral Pathol Med 41(1):34–39. https://doi.org/10.1111/j.1600-0714.2011.01068.x

Article  PubMed  Google Scholar 

Anand R, Pandiar D, Kamboj M (2020) Financial burden of oral squamous cell carcinoma in India. Oral Oncol 103:104528. https://doi.org/10.1016/j.oraloncology.2019.104528

Article  PubMed  Google Scholar 

Struckmeier AK, Buchbender M, Lutz R, Kesting M (2024) Improved recurrence rates and progression-free survival in primarily surgically treated oral squamous cell carcinoma - results from a German tertiary medical center. Clin Oral Investig 28(5):262. https://doi.org/10.1007/s00784-024-05644-z

Article  PubMed  PubMed Central  Google Scholar 

Zittel S, Moratin J, Horn D, Metzger K, Ristow O, Engel M, Mrosek J, Freier K, Hoffmann J, Freudlsperger C (2022) Clinical outcome and prognostic factors in recurrent oral squamous cell carcinoma after primary surgical treatment: a retrospective study. Clin Oral Investig 26(2):2055–2064. https://doi.org/10.1007/s00784-021-04186-y

Article  PubMed  Google Scholar 

Blatt S, Krüger M, Sagheb K, Barth M, Kämmerer PW, Al-Nawas B, Sagheb K (2022) Tumor recurrence and Follow-Up intervals in oral squamous cell carcinoma. J Clin Med 11(23):7061. https://doi.org/10.3390/jcm11237061

Article  PubMed  PubMed Central  Google Scholar 

Sousa AA, Caldeira PC, da Silva KD, de Aguiar MCF, Faria DM, de Moraes GM, Carvalho JR, Silva GS, Soares JMA, Porcaro-Salles JM (2021) Survival analysis of recurrent squamous cell carcinoma of the lower oral cavity treated by surgery. Int J Clin Exp Pathol 14(6):713–719

PubMed  PubMed Central  Google Scholar 

Alim N, Elsheikh M, Satti AA, Tabassum N, Suleiman AM (2024) Recurrence of oral squamous cell carcinoma in surgically treated patients at Khartoum Teaching Dental Hospital retrospective cross-sectional study. BMC Cancer 24(1):781. https://doi.org/10.1186/s12885-024-12562-6

Article  PubMed  PubMed Central  Google Scholar 

Wang Y, Yang T, Gan C, Wang K, Sun B, Wang M, Zhu F (2023) Temporal and spatial patterns of recurrence in oral squamous cell carcinoma, a single-center retrospective cohort study in China. BMC Oral Health 23(1):679. https://doi.org/10.1186/s12903-023-03204-7

Article  PubMed  PubMed Central  Google Scholar 

Sharma S, Satyanarayana L, Asthana S, Shivalingesh KK, Goutham BS, Ramachandra S (2018 Jan-Apr) Oral cancer statistics in India on the basis of first report of 29 population-based cancer registries. J Oral Maxillofac Pathol 22(1):18–26. https://doi.org/10.4103/jomfp.JOMFP_113_17

Kumar V, Sindhu VA, Rathanaswamy S, Jain J, Pogal JR, Akhtar N et al (2013) Cancers of upper gingivobuccal sulcus, hard palate and maxilla: a tertiary care centre study in North India. Natl J Maxillofac Surg 4(2):202–205. https://doi.org/10.4103/0975-5950.127652

Article  PubMed  PubMed Central  Google Scholar 

Gangane NM, Ghongade PV, Patil BU, Atram M (2024 Jan) Oral cavity cancer incidence and survival trends: a population-based study. J Cancer Res Ther 22. https://doi.org/10.4103/jcrt.jcrt_2720_22Epub ahead of print

Panta P, Sarode SC, Sarode GS, Patil S (2018) Chronic traumatic ulcer of lateral tongue’- An underestimated ‘oral potentially malignant disorder’? Oral Oncol 85:101–102. https://doi.org/10.1016/j.oraloncology.2018.08.019

Article  PubMed  Google Scholar 

Fitzpatrick SG, Cohen DM, Clark AN (2019) Ulcerated lesions of the oral mucosa: clinical and histologic review. Head Neck Pathol 13(1):91–102. https://doi.org/10.1007/s12105-018-0981-8

Article  PubMed  PubMed Central  Google Scholar 

Boldrup L, Coates PJ, Laurell G, Nylander K (2011) Differences in p63 expression in SCCHN tumours of different sub-sites within the oral cavity. Oral Oncol 47(9):861–865. https://doi.org/10.1016/j.oraloncology.2011.07.002

Article  CAS  PubMed  Google Scholar 

Vered M, Dayan D, Salo T (2011) The role of the tumour microenvironment in the biology of head and neck cancer: lessons from mobile tongue cancer. Nat Rev Cancer 11(5):382. https://doi.org/10.1038/nrc2982-c1. author reply 382

Article  CAS  PubMed