Global Retinoblastoma Study Group. Global retinoblastoma presentation and analysis by National income level. JAMA Oncol. 2020;6:685–95. https://doi.org/10.1001/jamaoncol.2019.6716.
Jain M, Rojanaporn D, Chawla B, Sundar G, Gopal L, Khetan V. Retinoblastoma in Asia. Eye. 2019;33:87–96. https://doi.org/10.1038/s41433-018-0244-7.
Atima MO, Idakwo U, Komolafe O, Eisuke S, Shintaro N, Balogun EO, et al. Presentation pattern and survival rate of retinoblastoma following chemotherapy: a prospective study. BMC Pediatr. 2023;23:538. https://doi.org/10.1186/s12887-023-04347-w.
Article PubMed PubMed Central Google Scholar
Kritfuangfoo T, Chokchaitanasin R, Tsutsumi WD, Rojanaporn D. Chapter 51 - Retinoblastoma—Metastatic. In: Ramasubramanian A, Shields CL, editors. Clin cases ocul oncol first ed [Internet]. New Delhi: Elsevier; 2025. pp. 241–5. [cited 2024 Dec 27]. https://doi.org/10.1016/B978-0-443-12049-7.00051-8.
Ma X, Li X, Sun Q, Luan F, Feng J. Molecular biological research on the pathogenic mechanism of retinoblastoma. Curr Issues Mol Biol Multidisciplinary Digit Publishing Inst. 2024;46:5307–21. https://doi.org/10.3390/cimb46060317.
Sethu Nagarajan R, Kim U, Shanthi R, Vanniarajan A. Investigation of GD2 synthase as a potential marker for retinoblastoma poor prognosis. Mol Biol Rep. 2025;52:372. https://doi.org/10.1007/s11033-025-10475-6.
Article CAS PubMed Google Scholar
Balaji S, Rao A, Saraswathi KK, Sethu Nagarajan R, Santhi R, Kim U, et al. Focused cancer pathway analysis revealed unique therapeutic targets in retinoblastoma. Med Oncol Northwood Lond Engl. 2024;41:168. https://doi.org/10.1007/s12032-024-02391-9.
Sinenko IL, Turnell-Ritson RC, Munier FL, Dyson PJ. The predictive capacity of in vitro preclinical models to evaluate drugs for the treatment of retinoblastoma. Exp Eye Res. 2023;230:109447. https://doi.org/10.1016/j.exer.2023.109447.
Article CAS PubMed Google Scholar
Hay M, Thomas DW, Craighead JL, Economides C, Rosenthal J. Clinical development success rates for investigational drugs. Nat Biotechnol. 2014;32:40–51. https://doi.org/10.1038/nbt.2786.
Article CAS PubMed Google Scholar
Van Norman GA. Limitations of animal studies for predicting toxicity in clinical trials: is it time to rethink our current approach? JACC Basic Transl Sci. 2019;4:845–54. https://doi.org/10.1016/j.jacbts.2019.10.008.
Article PubMed PubMed Central Google Scholar
Sinenko IL, Kuttler F, Simeonov V, Moulin A, Aouad P, Stathopoulos C, et al. Translational screening platform to evaluate chemotherapy in combination with focal therapy for retinoblastoma. Cancer Sci. 2023;114:3728–39. https://doi.org/10.1111/cas.15878.
Article CAS PubMed PubMed Central Google Scholar
Biju TS, Priya VV, Francis AP. Role of three-dimensional cell culture in therapeutics and diagnostics: an updated review. Drug Deliv Transl Res. 2023;13:2239–53. https://doi.org/10.1007/s13346-023-01327-6.
Article PubMed PubMed Central Google Scholar
Alves SR, Calori IR, Bi H, Tedesco AC. Characterization of glioblastoma spheroid models for drug screening and phototherapy assays. OpenNano. 2023;9:100116. https://doi.org/10.1016/j.onano.2022.100116.
Alefeld E, Haase A, Van Meenen D, Budeus B, Dräger O, Miroschnikov N, et al. In vitro model of retinoblastoma derived tumor and stromal cells for tumor microenvironment (TME) studies. Cell Death Dis Nat Publishing Group. 2024;15:905. https://doi.org/10.1038/s41419-024-07285-2.
Tang Z, Ma H, Mao Y, Ai S, Zhang P, Nie C, et al. Identification of stemness in primary retinoblastoma cells by analysis of stem-cell phenotypes and tumorigenicity with culture and xenograft models. Exp Cell Res. 2019;379:110–8. https://doi.org/10.1016/j.yexcr.2019.03.034.
Article CAS PubMed Google Scholar
Thirumalairaj K, Abraham A, Devarajan B, Gaikwad N, Kim U, Muthukkaruppan V, et al. A Stepwise strategy for rapid and cost-effective RB1 screening in Indian retinoblastoma patients. J Hum Genet Nat Publishing Group. 2015;60:547–52. https://doi.org/10.1038/jhg.2015.62.
Kischkel FC, Meyer C, Eich J, Nassir M, Mentze M, Braicu I, et al. Prediction of clinical response to drugs in ovarian cancer using the chemotherapy resistance test (CTR-test). J Ovarian Res. 2017;10:72. https://doi.org/10.1186/s13048-017-0365-9.
Article CAS PubMed PubMed Central Google Scholar
Balaji S, Santhi R, Kim U, Muthukkaruppan V, Priya CG, Vanniarajan A. Cancer stem cells with overexpression of neuronal markers enhance chemoresistance and invasion in retinoblastoma. Curr Cancer Drug Targets. 2020;20:710–9. https://doi.org/10.2174/1568009620666200504112711.
Article CAS PubMed Google Scholar
Appukuttan B, Biswas,Jyotirmay. Enucleation in retinoblastoma: pros and cons. Expert Rev Ophthalmol Taylor Francis. 2013;8:351–3. https://doi.org/10.1586/17469899.2013.826053.
Shields CL, Bas Z, Tadepalli S, Dalvin LA, Rao R, Schwendeman R, et al. Long-term (20-year) real-world outcomes of intravenous chemotherapy (chemoreduction) for retinoblastoma in 964 eyes of 554 patients at a single centre. Br J Ophthalmol. 2020;104:1548. https://doi.org/10.1136/bjophthalmol-2019-315572.
Nag A, Khetan V. Retinoblastoma – A comprehensive review, update and recent advances. Indian J Ophthalmol 2024;72(6):778–88. https://doi.org/10.4103/IJO.IJO_2414_23
King BA, Wilson MW, Kaluzny T, Meredith C, Overbey-Canon J, Chiang J, et al. Intravitreal carboplatin as salvage treatment for progressive vitreous disease in retinoblastoma: A phase I clinical trial. Ophthalmol Retina. 2023;7:354–9. https://doi.org/10.1016/j.oret.2022.11.003.
Cancela MB, Zugbi S, Winter U, Martinez AL, Sampor C, Sgroi M, et al. A decision process for drug discovery in retinoblastoma. Invest New Drugs. 2021;39:426–41. https://doi.org/10.1007/s10637-020-01030-0.
Chévez-Barrios P, Hurwitz MY, Louie K, Marcus KT, Holcombe VN, Schafer P, et al. Metastatic and nonmetastatic models of retinoblastoma. Am J Pathol Elsevier. 2000;157:1405–12. https://doi.org/10.1016/S0002-9440(10)64653-6.
Busch M, Philippeit C, Weise A, Dünker N. Re-characterization of established human retinoblastoma cell lines. Histochem Cell Biol. 2015;143:325–38. https://doi.org/10.1007/s00418-014-1285-z.
Article CAS PubMed Google Scholar
Zhou Z, Jiang H, Xia J, Zhang J. Comparison of the therapeutic effects of lobaplatin and carboplatin on retinoblastoma in vitro and in vivo. Int J Oncol. 2020;57:697–706. https://doi.org/10.3892/ijo.2020.5085.
Article CAS PubMed PubMed Central Google Scholar
Borah NA, Mittal R, Sucharita S, Rath S, Kaliki S, Patnaik S, et al. Aurora kinase A is overexpressed in human retinoblastoma and correlates with histopathologic High-Risk factors. Am J Pathol. 2024;194:1780–98. https://doi.org/10.1016/j.ajpath.2024.05.006.
Article CAS PubMed Google Scholar
Reinhard J, Wagner N, Krämer MM, Jarocki M, Joachim SC, Dick HB et al Expression changes and impact of the extracellular matrix on Etoposide resistant human retinoblastoma cell lines. Int J Mol Sci. 2020. https://doi.org/10.3390/ijms21124322.
Kong M, Han Y, Zhao Y, Zhang H. miR-512-3p overcomes resistance to cisplatin in retinoblastoma by promoting apoptosis induced by Endoplasmic reticulum stress. Med Sci Monit [Internet]. 2020. https://doi.org/10.12659/MSM.923817. [cited 2025 Apr 17];26.
Article PubMed PubMed Central Google Scholar
Winter U, Aschero R, Fuentes F, Buontempo F, Zugbi S, Sgroi M et al Tridimensional retinoblastoma cultures as vitreous seeds models for Live-Cell imaging of chemotherapy penetration. Int J Mol Sci. 2019. https://doi.org/10.3390/ijms20051077
Hebert TL, Wu X, Yu G, Goh BC, Halvorsen Y-DC, Wang Z, et al. Culture effects of epidermal growth factor (EGF) and basic fibroblast growth factor (bFGF) on cryopreserved human adipose-derived stromal/stem cell proliferation and adipogenesis. J Tissue Eng Regen Med. 2009;3:553–61. https://doi.org/10.1002/term.198.
Article CAS PubMed PubMed Central Google Scholar
Zhang L, Yu H, Yuan Y, Yu JS, Lou Z, Xue Y, et al. The necessity for standardization of glioma stem cell culture: a systematic review. Stem Cell Res Ther. 2020;11:84.
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