A century after its discovery, Chagas disease (CD) remains a serious public health issue, affecting 6 to 7 million people worldwide [[1], [2], [3]]. Although it has historically been concentrated in Latin American countries, the disease has increasingly affected non-endemic areas, such as the United States [[4], [5], [6]].
CD can progress from the acute phase to the chronic phase, where patients may present an indeterminate form or an involvement of the digestive and/or cardiac systems [2,6]. Among the primary clinical manifestations of CD, chagasic cardiomyopathy stands out as the most significant cause of morbidity and mortality in chagasic patients [5,7,8]. This condition is characterized by the presence of at least one typical electrocardiogram (ECG) abnormality, such as conduction disorders and ventricular ectopic beats [5,6,7,8,9].
The frequency and the main types of arrhythmias in the chagasic population are crucial for the diagnosis and prognosis of patients with CD, especially since ECG is a low-cost evaluation method [9]. Therefore, this systematic review with meta-analyses aims to evaluate the overall prevalence of cardiac arrhythmias in patients with CD.
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