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Effectiveness of Sulbactam/Durlobactam in carbapenem-resistant Acinetobacter baumannii pulmonary infection complicated with carbapenem-resistant Enterobacterales and/or carbapenem-resistant Pseudomonas aeruginosa infection: A prospective, multicenter, cohort study

Drug Resistance Updates

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Adaptive lineage plasticity drives multidrug resistance to KRAS-EGFR targeted therapy

Drug Resistance Updates

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Corrigendum to “RNF26 regulating tumor immunogenicity of hepatocellular carcinoma by degrading GRP78 and instigating ER stress” [Drug Resist. Updat. 86 (2026) 101375]

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ZDHHC16-induced GPX2 S-palmitoylation promotes lenvatinib resistance and inhibits lenvatinib-induced immunogenic cell death in hepatocellular carcinoma

Drug Resistance Updates

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A multifunctional antimicrobial peptide with cell-penetrating and β-lactam-potentiating activities for combating methicillin-resistant Staphylococcus aureus and carbapenem-resistant Enterobacteriaceae infections

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MZF1-mediated GAPDH overexpression drives glycolytic reprogramming and neuroendocrine progression in advanced prostate cancer

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Targeting a novel metabolic vulnerability of non-small cell lung cancer to fatty acid oxidation surmounts chemoresistance

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ITPKB suppresses ER calcium release to promote CXCL9 expression and enhance immunotherapy sensitivity in triple-negative breast cancer

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ZBED6-driven nucleotide metabolic reprogramming improves sensitivity to anti-PD1 therapy in NK/T cell lymphoma

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OGT-mediated O-GlcNAcylation of BICD2 drives gemcitabine resistance in pancreatic cancer via accelerating G2/M cell cycle progression

Drug Resistance Updates

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Tumor-intrinsic PHGDH inhibition sensitizes colorectal cancer to PD-1 blockade via α-ketoglutarate–mediated macrophage reprogramming

Drug Resistance Updates

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Piperidine-derived resensitizers revive aminoglycoside capacity against persister cells of Pseudomonas aeruginosa in vivo

Drug Resistance Updates

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Resistance to CAR-based cell therapy: Mechanisms and overcoming strategies

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Immunotherapy in cancer: Mechanisms and strategies to overcome resistance

Drug Resistance Updates

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Biomimetic delivery systems for overcoming drug resistance in gastrointestinal cancers

Drug Resistance Updates

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Consensus on standardized later-line systemic therapy for hepatocellular carcinoma

Drug Resistance Updates

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Extracellular matrix stiffness and mechanotransduction in cancer drug resistance

Drug Resistance Updates

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Clinical Profile and Induction Protocol of Video Electroencephalography in Children with Functional Neurological Symptom Disorder

To describe the clinical features and a structure, non-invasive induction protocol performed during video electroencephalo...

Indian Pediatrics

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Seroprotection Against Mumps in MMR Vaccinated Children Aged 9–12 Years: A Cross-Sectional Study

To estimate the proportion of children aged 9–12 years with seroprotective antibody titers against mumps fo...

Indian Pediatrics

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Tele-training Versus In-Person Training in Early Intervention for Parents of Children with Cerebral Palsy: A Pilot Randomized Controlled Trial

Tele-training for parent-mediated intervention in children with cerebral palsy has been inadequately evaluated against con...

Indian Pediatrics

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A Multicenter Study for Validation of the New Pediatric Advanced Life Support Tape for Indian Children

Accurate weight estimation is essential for drug dosing and equipment selection in pediatric emergencies. A new Pediatric ...

Indian Pediatrics

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Intrapleural Fibrinolytic Therapy Versus Video-Assisted Thoracoscopic Surgery, as the Initial Treatment Modality, in Children with Empyema Thoracis: A Systematic Review and Meta-Analysis

Intrapleural fibrinolytic therapy (IPFT) is frequently used in empyema thoracis as the initial treatment modality. However...

Indian Pediatrics

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Comparative Efficacy, Safety, and Cost of Different Intrapleural Fibrinolytic Agents for the Management of Empyema Thoracis in Children: A Systematic Review

Pediatric empyema thoracis is a serious complication of bacterial pneumonia, and poses management challenges due to the ab...

Indian Pediatrics

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Comparative Proteomics Analysis of Serum Exosomes Reveals Distinct Infection Profiles and Potential Biomarkers for Pediatric Tuberculosis

The primary objective of the study was to investigate the proteomic content of serum exosomes from pediatric patients with...

Indian Pediatrics

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Gastric retention for cardiovascular therapy: matching drug properties, dosage-form design, and translational evidence

Drug Discovery Today

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Toward sustainable therapeutics: integrating regenerative medicine into pharmacological sustainability frameworks

Drug Discovery Today

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Precision targeting in prostate cancer: Mechanistic drivers and the evolving clinical pipeline

Drug Discovery Today

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