Device-assisted enteroscopy (DAE) is an advanced endoscopic technique for diagnosing and treating small-bowel diseases, typically performed in specialized tertiary centers. However, real-world data reveal considerable variability in performance among centers, due to differences in expertise, protocols, and available resources. As with other endoscopic procedures, systematically assessing clinical outcomes and benchmarking performance metrics against quality indicators is essential for ensuring standardized care, optimizing procedural effectiveness, and improving patient outcomes. Consequently, international scientific societies have established quality indicators for DAE. This review outlines the current quality indicators for DAE and critically examines their relevance in daily clinical practice, addressing the challenges of maintaining consistent, high-quality care.