Available online 23 April 2025, 102012

Small bowel capsule endoscopy (SBCE) is widely regarded as the gold standard for the diagnosis of small bowel disorders, offering a minimally invasive and highly accurate diagnostic method. To improve diagnostic precision, international societies have established guidelines and quality initiatives; however, real-world implementation remains inconsistent, with numerous centers failing to meet the recommended benchmarks. Key challenges include variability in bowel preparation, the management of identified pathology, and adherence to recommended timelines, particularly following overt bleeding. Achieving high-quality SBCE is essential for improving clinical outcomes and ensuring the reliability of procedural benchmarks. Future research should focus on exploring the potential role of artificial intelligence in improving the quality of capsule endoscopy, evaluating the training requirements for clinicians and trainees, optimizing strategies to increase completion rates, and standardizing bowel preparation protocols across clinical settings.

Small-bowel

Small intestine

Mid-gut

© 2025 The Authors. Published by Elsevier Ltd.