Abdullaeva S, Chubarev V, Valeeva A, Preferanskaya N, Neganova M, Smolyarchuk E, Liu J, Sukocheva O, Samsonov M, Alyautdin R (2025) Analysis of clinical success and molecular mechanisms of action of novel anti-glioblastoma drugs: a review. Curr Med Chem 32:1082

Article  PubMed  CAS  Google Scholar 

Agarwal S, Muniyandi P, Maekawa T, Kumar DS (2018) Vesicular systems employing natural substances as promising drug candidates for MMP inhibition in glioblastoma: a nanotechnological approach. Int J Pharm 551(1–2):339–361

Article  PubMed  CAS  Google Scholar 

Aghajani M, Jalilzadeh N, Aghebati-Maleki A, Yari A, Tabnak P, Mardi A, Saeedi H, Aghebati-Maleki L, Baradaran B (2024) Current approaches in glioblastoma multiforme immunotherapy. Clin Transl Oncol 26(7):1584–1612

Article  PubMed  Google Scholar 

Akinyemi AO, Simpson KE, Oyelere SF, Nur M, Ngule CM, Owoyemi BC, Ayarick VA, Oyelami FF, Obaleye O, Esoe DP, Liu X (2023) Unveiling the dark side of glucose-regulated protein 78 (GRP78) in cancers and other human pathology: a systematic review. Mol Med 29(1):112

Article  PubMed  PubMed Central  CAS  Google Scholar 

Al MO (2024) Peptide Therapeutics: unveiling the potential against cancer—a journey through 1989. Cancers 16(5):1032

Article  Google Scholar 

Al Rihani SB, Darakjian LI, Deodhar M, Dow P, Turgeon J, Michaud V (2021) Disease-induced modulation of drug transporters at the blood–brain barrier level. Int J Mol Sci 22(7):3742

Article  PubMed  PubMed Central  CAS  Google Scholar 

Alausa A, Victor UC, Fadahunsi OS, Owolabi N, Adeniji A, Olatinwo M, Ogunlana AT, Olaleke B, Balogun TA, Ogundepo S, Adegbola PI (2022) Checkpoints and immunity in cancers: Role of GNG12. Pharmacol Res 1(180):106242

Article  Google Scholar 

Albinhassan TH, Alharbi BM, AlSuhaibani ES, Mohammad S, Malik SS (2025) Small heat shock proteins: protein aggregation amelioration and neuro-and age-protective roles. Int J Mol Sci 26(4):1525

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ameratunga M, Coleman N, Welsh L, Saran F, Lopez J (2018) CNS cancer immunity cycle and strategies to target this for glioblastoma. Oncotarget 9(32):22802

Article  PubMed  PubMed Central  Google Scholar 

Andreu-Sanz D, Kobold S (2023) Role and potential of different T helper cell subsets in adoptive cell therapy. Cancers 15(6):1650

Article  PubMed  PubMed Central  CAS  Google Scholar 

Arbab AS, Ali MM (2020) Glioblastoma: targeting angiogenesis and tyrosine kinase pathways. Novel Approaches Cancer Study 4(5):398

Google Scholar 

Ashi MO, Mami-Chouaib F, Corgnac S (2022) Mutant and non-mutant neoantigen-based cancer vaccines: recent advances and future promises. Explor Target Anti-Tumor Ther 3(6):746

Article  CAS  Google Scholar 

Bae T, Hallis SP, Kwak MK (2024) Hypoxia, oxidative stress, and the interplay of HIFs and NRF2 signaling in cancer. Exp Mol Med 56(3):501–514

Article  PubMed  PubMed Central  CAS  Google Scholar 

Bagchi S, Yuan R, Engleman EG (2021) Immune checkpoint inhibitors for the treatment of cancer: clinical impact and mechanisms of response and resistance. Annu Rev Pathol 16(1):223–249

Article  PubMed  CAS  Google Scholar 

Bakowski K, Vogel S (2022) Evolution of complexity in non-viral oligonucleotide delivery systems: from gymnotic delivery through bioconjugates to biomimetic nanoparticles. RNA Biol 19(1):1256–1275

Article  PubMed  PubMed Central  CAS  Google Scholar 

Baldanzi G (2022) Immune checkpoint receptors signaling in T cells. Int J Mol Sci 23(7):3529

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ballestín A, Armocida D, Ribecco V, Seano G (2024) Peritumoral brain zone in glioblastoma: biological, clinical and mechanical features. Front Immunol 29(15):1347877

Article  Google Scholar 

Banks WA (2009) Characteristics of compounds that cross the bloodbrain barrier. BMC Neurol 9(Suppl 1):S3

Article  PubMed  PubMed Central  Google Scholar 

Barcan EN, Duta C, Staicu GA, Artene SA, Alexandru O, Costachi A, Pirvu AS, Tache DE, Stoian I, Popescu SO, Tataranu LG (2025) Current research trends in glioblastoma: focus on receptor tyrosine kinases. Int J Mol Sci 26(8):3503

Article  PubMed  PubMed Central  CAS  Google Scholar 

Bausart, Préat V, Malfanti A (2022) Immunotherapy for glioblastoma: the promise of combination strategies. J Exp Clin Cancer Res 41(1):35

Article  PubMed  PubMed Central  CAS  Google Scholar 

Berger TR, Wen PY, Lang-Orsini M, Chukwueke UN (2022) World Health Organization 2021 classification of central nervous system tumors and implications for therapy for adult-type gliomas: a review. JAMA Oncol 8(10):1493–1501

Article  PubMed  Google Scholar 

Bernardo-Castro S, Sousa JA, Brás A, Cecília C, Rodrigues B, Almendra L, Machado C, Santo G, Silva F, Ferreira L, Santana I (2020) Pathophysiology of blood–brain barrier permeability throughout the different stages of ischemic stroke and its implication on hemorrhagic transformation and recovery. Front Neurol 11:594672 (Dec 9;)

Article  PubMed  PubMed Central  Google Scholar 

Berro A, Assi A, Farhat M, Hatoum L, Saad JP, Mohanna R, Bechara AM, Prince G, Hachem MC, Zalaquett Z, Kourie HR (2024) Unlocking Hope: Anti-VEGFR inhibitors and their potential in glioblastoma treatment. Crit Rev Oncol Hematol 25:104365

Article  Google Scholar 

Bhardwaj R, Suzuki A, Leland P, Joshi BH, Puri RK (2018) Identification of a novel role of IL-13Rα2 in human Glioblastoma multiforme: interleukin-13 mediates signal transduction through AP-1 pathway. J Transl Med 16:1–3

Article  Google Scholar 

Bhattacharya R, Brown JS, Gatenby RA, Ibrahim-Hashim A (2024) A gene for all seasons: the evolutionary consequences of HIF-1 in carcinogenesis, tumor growth and metastasis. Seminars in cancer biology. Academic Press

Google Scholar 

Bigos KJ, Quiles CG, Lunj S, Smith DJ, Krause M, Troost EG, West CM, Hoskin P, Choudhury A (2024) Tumour response to hypoxia: understanding the hypoxic tumour microenvironment to improve treatment outcome in solid tumours. Front Oncol 30(14):1331355

Article  Google Scholar 

Blades R, Ittner LM, Tietz O (2023) Peptides for trans-blood–brain barrier delivery. J Labelled Comp Radiopharm 66(9):237–248

Article  PubMed  PubMed Central  CAS  Google Scholar 

Bouayad-Gervais S, St-Cyr DJ, Courcelles M, Bonneil E, Gohard FH, Thibault P, Earnshaw WC, Tyers M (2022) Head-to-tail cyclization of side chain-protected linear peptides to recapitulate genetically-encoded cyclized peptides. Pept Sci 114(3):e24254

Article  CAS  Google Scholar 

Branco F, Cunha J, Mendes M, Vitorino C, Sousa JJ (2024) Peptide-hitchhiking for the development of nanosystems in Glioblastoma. ACS Nano 18(26):16359–16394

Article  PubMed  PubMed Central  CAS  Google Scholar 

Brat DJ, Castellano-Sanchez AA, Hunter SB, Pecot M, Cohen C, Hammond EH, Devi SN, Kaur B, Van Meir EG (2004) Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell population. Can Res 64(3):920–927

Article  CAS  Google Scholar 

Bridgen DT, Gilchrist CL, Richardson WJ, Isaacs RE, Brown CR, Yang KL, Chen J, Setton LA (2013) Integrin-mediated interactions with extracellular matrix proteins for nucleus pulposus cells of the human intervertebral disc. J Orthop Res 31(10):1661–1667

Article  PubMed  CAS  Google Scholar 

Buckle I, Guillerey C (2021) Inhibitory receptors and immune checkpoints regulating natural killer cell responses to cancer. Cancers 13(17):4263

Article  PubMed  PubMed Central  CAS  Google Scholar 

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