Molè MA, Coorens THH, Shahbazi MN et al (2021) A single cell characterisation of human embryogenesis identifies pluripotency transitions and putative anterior hypoblast centre. Nat Commun 12:3679

Article  PubMed  PubMed Central  Google Scholar 

Wolpert L (1999) Vertebrate limb development and malformations. Pediatr Res 46:247–254

Article  CAS  PubMed  Google Scholar 

Lin GH, Zhang L (2020) Apical ectodermal ridge regulates three principal axes of the developing limb. J Zhejiang Univ Sci B 21:757–766

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ben Sason Y, Oksenberg A, Sobel JA et al (2023) Characteristics of patients with positional OSA according to ethnicity and the identification of a novel phenotype-lateral positional patients: A multi-ethnic study of atherosclerosis (MESA) study. J Clin Sleep Med 19:529–538

Article  PubMed  PubMed Central  Google Scholar 

Huang ST, Lin JJ, Chang CS et al (1991) A dental anthropological study of Chinese in Taiwan. Craniofacial morphology. Gaoxiong Yi Xue Ke Xue Za Zhi 7:562–581

CAS  PubMed  Google Scholar 

Singh GD, McNamara JA Jr, Lozanoff S (1999) Allometry of the cranial base in prepubertal Korean subjects with class III malocclusions: finite element morphometry. Angle Orthod 69:507–514

CAS  PubMed  Google Scholar 

Lew KK, Foong WC, Loh E (1993) Malocclusion prevalence in an ethnic Chinese population. Aust Dent J 38:442–449

Article  CAS  PubMed  Google Scholar 

Banabilh SM, Suzina AH, Dinsuhaimi S et al (2007) Cranial base and airway morphology in adult malays with obstructive sleep apnoea. Aust Orthod J 23:89–95

PubMed  Google Scholar 

Parsons TE, Downey CM, Jirik FR et al (2015) Mind the gap: genetic manipulation of basicranial growth within synchondroses modulates calvarial and facial shape in mice through epigenetic interactions. PLoS ONE 10:e0118355

Article  PubMed  PubMed Central  Google Scholar 

Miyamura K, Nakashima D, Nakayama T et al (2025) Morphology of nasal septal deviation in obstructive sleep apnea patients and its treatment method. Laryngoscope 135:1520–1524

Article  CAS  PubMed  Google Scholar 

Sperber GH (2001) Craniofacial Development. BC Decker, Hamilton

Google Scholar 

Osman SAA, Abu Alhaija E, AlWahadni AM et al (2024) Evaluation of nasal septal deviation and maxillary bone and nasal airway dimensions and volumes using cone-beam computed tomography in patients with unilateral palatal canine displacement: a retrospective study. Angle Orthod 94:421–431

Article  PubMed  PubMed Central  Google Scholar 

Singh GD, Battle J (2025) Integrative treatment of obstructive sleep apnea: principles and practice. J Clin Sleep Med 21:1591–1596

Article  PubMed  PubMed Central  Google Scholar 

Saunders NC, Birchall MA, Armstrong SJ et al (1998) Morphometry of paranasal sinus anatomy in chronic rhinosinusitis: a pilot study. Arch Otolaryngol Head Neck Surg 124:656–658

Article  CAS  PubMed  Google Scholar 

Chaplain MAJ, Singh GD, McLachlan JC (1999) On growth and form: Spatio-temporal patterning in biology. John Wiley and Sons Publishers, England

Google Scholar 

Callander JK, Chang JL (2024) Treatment of the nose for patients with sleep apnea. Otolaryngol Clin North Am 57:491–500

Article  PubMed  Google Scholar 

Cai Y, Goldberg AN, Chang JL (2020) The nose and nasal breathing in sleep apnea. Otolaryngol Clin North Am 53:385–395

Article  PubMed  Google Scholar 

Huang CC, Lee CC, Wu PW et al (2023) Sleep impairment in patients with empty nose syndrome. Rhinology 61:47–53

PubMed  Google Scholar 

Dao N, Cozean C, Chernyshev O et al (2023) Retrospective analysis of real-world data for the treatment of obstructive sleep apnea with slow maxillary expansion using a unique expansion dental appliance (DNA). Pathophysiology 30:99–208

Article  Google Scholar 

Brunetto DP, Moschik CE, Dominguez-Mompell R et al (2022) Mini-implant assisted rapid palatal expansion (MARPE) effects on adult obstructive sleep apnea (OSA) and quality of life: a multi-center prospective controlled trial. Prog Orthod 23:3

Article  PubMed  PubMed Central  Google Scholar 

Bach N, Tuomilehto H, Gauthier C et al (2013) The effect of surgically assisted rapid maxillary expansion on sleep architecture: an exploratory risk study in healthy young adults. J Oral Rehabil 40:818–825

Article  CAS  PubMed  Google Scholar 

Yoon A, Guilleminault C, Zaghi S et al (2020) Distraction Osteogenesis Maxillary Expansion (DOME) for adult obstructive sleep apnea patients with narrow maxilla and nasal floor. Sleep Med 65:172–176

Article  PubMed  Google Scholar 

Colak O, Paredes NA, Elkenawy I et al (2020) Tomographic assessment of palatal suture opening pattern and pterygopalatine suture disarticulation in the axial plane after midfacial skeletal expansion. Prog Orthod 21:21

Article  PubMed  PubMed Central  Google Scholar 

Liu SY, Guilleminault C, Huon LK et al (2017) Distraction Osteogenesis Maxillary Expansion (DOME) for adult obstructive sleep apnea patients with high arched palate. Otolaryngol Head Neck Surg 157:345–348

Article  PubMed  Google Scholar 

Hanai U, Muramatsu H, Akamatsu T (2025) Maxillary bone fracture due to a miniscrew-assisted rapid maxillary expansion: A case report. J Clin Med 14:1928

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mitani Y, Banabilh SM, Singh GD (2010) Craniofacial changes in patients with Class III malocclusion treated with the RAMPA system. Int J Orthod 21:19–25

Google Scholar 

Martínez-Abadías N, Motch SM, Pankratz TL et al (2013) Tissue-specific responses to aberrant FGF signaling in complex head phenotypes. Dev Dyn 242:80–94

Article  PubMed  Google Scholar 

Luna-Paredes C, Antón-Pacheco JL, García Hernández G et al (2012) Screening for symptoms of obstructive sleep apnea in children with severe craniofacial anomalies: Assessment in a multidisciplinary unit. Int J Pediatr Otorhinolaryngol 76:1767–1770

Article  PubMed  Google Scholar 

Dowgierd K, Larysz D, Szymor P et al (2020) Alterations of upper airway volume caused by Le Fort III osteodistraction in children. J Craniomaxillofac Surg 48:825–831

Article  PubMed  Google Scholar 

Kambara T (1977) Dentofacial changes produced by extraoral forward force in the Macaca irus. Am J Orthod 71:249–277

Article  CAS  PubMed  Google Scholar 

de Beer GR, Huxley JS (1934) The elements of experimental embryology. Cambridge University Press, Cambridge

Google Scholar 

van der Klaauw CJ (1948–1952) Size and position of the functional components of the skull. Arch Neerland Zool 8:1–555

Moss ML, Young RW (1960) A functional approach to craniology. Am J Phys Anthropol 18:281–292

Article  CAS  PubMed  Google Scholar 

Kokich VG (1986) Biology of sutures. In: Cohen MM (ed) Craniosynostosis: Diagnosis, Evaluation, and Management. Raven Press, New York, pp 81–103

Google Scholar 

Kawashima S, Niikuni N, Chia-hung L et al (2000) Cephalometric comparisons of craniofacial and upper airway structures in young children with obstructive sleep apnea syndrome. Ear Nose Throat J 79:499–502, 505-506

Article  CAS  PubMed  Google Scholar 

Kazmierski RH (2024) Obstructive sleep apnea: what is an orthodontist’s role? Prog Orthod 25:21

Article  PubMed  PubMed Central  Google Scholar 

Korngut R (2010) Case study: a persistent positive outcome treating OSA with a MAD following the treatment protocol. Dialogue 1:26–27

Google Scholar 

Sutherland K, Cistulli P (2011) Mandibular advancement splints for the treatment of sleep apnea syndrome. Swiss Med Wkly 141:w13276

Article