The centrosome was first described in the late 19th century, independently by Theodor Boveri and Edouard Van Beneden, who observed its role in cell division and embryonic development (reviewed in Ref. [1]). Due to the unavailability of methods to investigate the centrosome, our understanding of its biology remained limited for nearly a century. However, in the last 25 years, technological advances, such as reverse genetics screens, sensitive proteomics, and high-resolution microscopy, including, more recently, cryoEM and sample preparation techniques, such as ExM [2], have strongly enhanced our ability to investigate centrosome structure and function in different tissues, organisms, and disease states. This review will discuss those recent advancements and their implications, emphasising developments from the last two years.