Editorial overview: 3Rs update: a new era in cellular identity and therapeutic plasticity

Jianlong Wang is a tenured Professor of Medicine at Columbia University Irving Medical Center and a core faculty member of the Columbia Center for Human Development and Stem Cell Therapies. His research investigates the transcriptional, translational, and epigenetic regulation of pluripotency, stem cell fate decisions, and early embryonic development. Dr. Wang has advanced the field through pioneering proteomic and genomic mapping of pluripotency networks, as well as the generation of innovative in vivo models for mechanistic interrogation. His NIH-funded work has recently expanded to include the study of nucleolar dynamics, RNA modifications, and stem cell tumorigenicity, contributing transformative insights to both stem cell biology and regenerative medicine.

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