Lloyd-Jones DM. Cardiovascular risk prediction: basic concepts, current status, and future directions. Circulation. 2010;121(15):1768–77. https://doi.org/10.1161/CIRCULATIONAHA.109.849166.

Article  PubMed  Google Scholar 

Weber C, Noels H. Atherosclerosis: current pathogenesis and therapeutic options. Nat Med. 2011;17(11):1410–22. https://doi.org/10.1038/nm.2538.

Article  CAS  PubMed  Google Scholar 

Baldrighi M, Mallat Z, Li X. NLRP3 inflammasome pathways in atherosclerosis. Atherosclerosis. 2017;267:127–38. https://doi.org/10.1016/j.atherosclerosis.2017.10.027.

Article  CAS  PubMed  Google Scholar 

Poznyak AV, Nikiforov NG, Markin AM, et al. Overview of OxLDL and its impact on cardiovascular health: focus on atherosclerosis. Front Pharmacol. 2021;11:613780. https://doi.org/10.3389/fphar.2020.613780.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wu MY, Li CJ, Hou MF, et al. New insights into the role of inflammation in the pathogenesis of atherosclerosis. Int J Mol Sci. 2017;18(10):2034. https://doi.org/10.3390/ijms18102034.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Moore KJ, Tabas I. Macrophages in the pathogenesis of atherosclerosis. Cell. 2011;145(3):341–55. https://doi.org/10.1016/j.cell.2011.04.005.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Doran AC, Yurdagul A Jr, Tabas I. Efferocytosis in health and disease. Nat Rev Immunol. 2020;20(4):254–67. https://doi.org/10.1038/s41577-019-0240-6.

Article  CAS  PubMed  Google Scholar 

Bäck M, Yurdagul A Jr, Tabas I, et al. Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities. Nat Rev Cardiol. 2019;16(7):389–406. https://doi.org/10.1038/s41569-019-0169-2.

Article  PubMed  PubMed Central  Google Scholar 

Yin Y, Li X, Sha X, et al. Early hyperlipidemia promotes endothelial activation via a caspase-1-sirtuin 1 pathway. Arterioscler Thromb Vasc Biol. 2015;35(4):804–16. https://doi.org/10.1161/ATVBAHA.115.305282.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liang Y, Xu XD, Xu X, et al. Linc00657 promoted pyroptosis in THP-1-derived macrophages and exacerbated atherosclerosis via the miR-106b-5p/TXNIP/NLRP3 axis. Int J Biol Macromol. 2023;253(4):126953. https://doi.org/10.1016/j.ijbiomac.2023.126953.

Article  CAS  PubMed  Google Scholar 

Li H, Zhao Q, Liu D, et al. Cathepsin B aggravates atherosclerosis in ApoE-deficient mice by modulating vascular smooth muscle cell pyroptosis through NF-κB/NLRP3 signaling pathway. PLoS ONE. 2024;19(1):e0294514. https://doi.org/10.1371/journal.pone.0294514.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang Y, Chen X, Gueydan C, et al. Plasma membrane changes during programmed cell deaths. Cell Res. 2018;28(1):9–21. https://doi.org/10.1038/cr.2017.133.

Article  CAS  PubMed  Google Scholar 

Xia S, Hollingsworth LR 4th, Wu H. Mechanism and regulation of Gasdermin-mediated cell death. Cold Spring Harb Perspect Biol. 2020;12(3):a036400. https://doi.org/10.1101/cshperspect.a036400.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang Y, Gao W, Shi X, et al. Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin. Nature. 2017;547(7661):99–103. https://doi.org/10.1038/nature22393.

Article  CAS  PubMed  Google Scholar 

Karki R, Sharma BR, Tuladhar S, et al. Synergism of TNF-α and IFN-γ triggers inflammatory cell death tissue damage and mortality in SARS-CoV-2 infection and cytokine shock syndromes. Cell. 2021;184(1):149-168.e17. https://doi.org/10.1016/j.cell.2020.11.025.

Article  CAS  PubMed  Google Scholar 

Kayagaki N, Warming S, Lamkanfi M, et al. Non-canonical inflammasome activation targets caspase-11. Nature. 2011;479(7371):117–21. https://doi.org/10.1038/nature10558.

Article  CAS  PubMed  Google Scholar 

Burdette BE, Esparza AN, Zhu H, et al. Gasdermin D in pyroptosis. Acta Pharm Sin B. 2021;11(9):2768–82. https://doi.org/10.1016/j.apsb.2021.02.006.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wei X, Xie F, Zhou X, et al. Role of pyroptosis in inflammation and cancer. Cell Mol Immunol. 2022;19(9):971–92. https://doi.org/10.1038/s41423-022-00905-x.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shi J, Gao W, Shao F. Pyroptosis: Gasdermin-mediated programmed necrotic cell death. Trends Biochem Sci. 2017;42(4):245–54. https://doi.org/10.1016/j.tibs.2016.10.004.

Article  CAS  PubMed  Google Scholar 

Halle A, Hornung V, Petzold GC, et al. 2008 The NALP3 inflammasome is involved in the innate immune response to amyloid-beta. Nat Immunol. 9(8) 857–865. https://https://doi.org/10.1038/ni.1636.

YAachoui Y, Sagulenko V, Miao EA, et al. 2013 Inflammasome-mediated pyroptotic and apoptotic cell death, and defense against infection. Curr Opin Microbiol. 16(3) 319–326. https://https://doi.org/10.1016/j.mib.2013.04.004.

Yu P, Zhang X, Liu N, et al. Pyroptosis: mechanisms and diseases. Signal Transduct Target Ther. 2021;6(1):128. https://doi.org/10.1038/s41392-021-00507-5.

Article  PubMed  PubMed Central  Google Scholar 

Murao A, Aziz M, Wang H, et al. Release mechanisms of major DAMPs. Apoptosis. 2021;26(3–4):152–62. https://doi.org/10.1007/s10495-021-01663-3.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhaolin Z, Jiaojiao C, Peng W, et al. OxLDL induces vascular endothelial cell pyroptosis through miR-125a-5p/TET2 pathway. J Cell Physiol. 2019;234(5):7475–91. https://doi.org/10.1002/jcp.27509.

Article  CAS  PubMed  Google Scholar 

Xu YJ, Zheng L, Hu YW, et al. Pyroptosis and its relationship to atherosclerosis. Clin Chim Acta. 2018;476:28–37. https://doi.org/10.1016/j.cca.2017.11.005.

Article  CAS  PubMed  Google Scholar 

Karasawa T, Takahashi M. Role of NLRP3 inflammasomes in atherosclerosis. J Atheroscler Thromb. 2017;24(5):443–51. https://doi.org/10.5551/jat.RV17001.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu Y, Tie L. Apolipoprotein M and sphingosine-1-phosphate complex alleviates TNF-α-induced endothelial cell injury and inflammation through PI3K/AKT signaling pathway. BMC Cardiovasc Disord. 2019;19(1):279. https://doi.org/10.1186/s12872-019-1263-4.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ruiz M, Frej C, Holmér A, et al. High-density lipoprotein-associated apolipoprotein M limits endothelial inflammation by delivering sphingosine-1-phosphate to the sphingosine-1-phosphate receptor 1. Arterioscler Thromb Vasc Biol. 2017;37(1):118–29. https://doi.org/10.1161/ATVBAHA.116.308435.

Article  CAS  PubMed  Google Scholar 

Wu X, Zhang H, Qi W, et al. Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis. Cell Death Dis. 2018;9(2):171. https://doi.org/10.1038/s41419-017-0257-3.

Article  CAS