Serial Tumour Volume Reduction During Chemoradiotherapy in Cervical Cancer: Insights from Ultrasound-Based Monitoring in a Resource-Constrained Setting

Pötter R, Tanderup K, Kirisits C, de Leeuw A, Kirchheiner K, Nout R, et al. The EMBRACE II study: the outcome and prospect of two decades of evolution within the GEC-ESTRO GYN working group and the EMBRACE studies. Clin Transl Radiat Oncol. 2018;9(11):48–60. https://doi.org/10.1016/j.ctro.2018.01.001.

Article  PubMed  PubMed Central  Google Scholar 

Viswanathan AN, Thomadsen B, American Brachytherapy Society Cervical Cancer Recommendations Committee, American Brachytherapy Society. American Brachytherapy Society consensus guidelines for locally advanced carcinoma of the cervix. Part I: general principles. Brachyther. 2012;11(1):33–46. https://doi.org/10.1016/j.brachy.2011.07.003.

Article  Google Scholar 

Narayan K, van Dyk S, Bernshaw D, Khaw P, Mileshkin L, Kondalsamy-Chennakesavan S. Ultrasound guided conformal brachytherapy of cervix cancer: survival, patterns of failure, and late complications. J Gynecol Oncol. 2014. https://doi.org/10.3802/jgo.2014.25.3.206.

Article  PubMed  PubMed Central  Google Scholar 

van Dyk S, Kondalsamy-Chennakesavan S, Schneider M, Bernshaw D, Narayan K. Comparison of measurements of the uterus and cervix obtained by magnetic resonance and transabdominal ultrasound imaging to identify the brachytherapy target in patients with cervix cancer. Int J Radiat Oncol Biol Phys. 2014;88(4):860–5. https://doi.org/10.1016/j.ijrobp.2013.12.004.

Article  PubMed  Google Scholar 

Pötter R, Georg P, Dimopoulos JC, Grimm M, Berger D, Nesvacil N, et al. Clinical outcome of protocol based image (MRI) guided adaptive brachytherapy combined with 3D conformal radiotherapy with or without chemotherapy in patients with locally advanced cervical cancer. Radiother Oncol. 2011;100(1):116–23. https://doi.org/10.1016/j.radonc.2011.07.012.

Article  PubMed  PubMed Central  Google Scholar 

Mayr NA, Yuh WT, Zheng J, Ehrhardt JC, Sorosky JI, Magnotta VA, et al. Tumor size evaluated by pelvic examination compared with 3-D MR quantitative analysis in the prediction of outcome for cervical cancer. Int J Radiat Oncol Biol Phys. 1997;39(2):395–404. https://doi.org/10.1016/s0360-3016(97)00318-0.

Article  CAS  PubMed  Google Scholar 

Narayan K, Fisher R, Bernshaw D. Significance of tumor volume and corpus uteri invasion in cservical cancer patients treated by radiotherapy. Int J Gynecol Cancer. 2006;16(2):623–30. https://doi.org/10.1111/j.1525-1438.2006.00379.x.

Article  CAS  PubMed  Google Scholar 

Srivastava S, Saini SK, Dixit AK, Dwivedi D. Prognostic significance of tumor volume as determined on 3D ultrasound scan in uterine cervix cancer treated by radiotherapy. J Cancer Res Ther. 2017;13(2):324–8. https://doi.org/10.4103/0973-1482.183201.

Article  PubMed  Google Scholar 

Wang JZ, Mayr NA, Zhang D, Li K, Grecula JC, Montebello JF, et al. Sequential magnetic resonance imaging of cervical cancer: the predictive value of absolute tumor volume and regression ratio measured before, during, and after radiation therapy. Cancer. 2010;116(21):5093–101. https://doi.org/10.1002/cncr.25260.

Article  PubMed  PubMed Central  Google Scholar 

Dimopoulos JC, Schard G, Berger D, Lang S, Goldner G, Helbich T, et al. Systematic evaluation of MRI findings in different stages of treatment of cervical cancer: potential of MRI on delineation of target, pathoanatomic structures, and organs at risk. Int J Radiat Oncol Biol Phys. 2006;64(5):1380–8. https://doi.org/10.1016/j.ijrobp.2005.10.017.

Article  PubMed  Google Scholar 

Mayr NA, Taoka T, Yuh WT, Denning LM, Zhen WK, Paulino AC, et al. Method and timing of tumor volume measurement for outcome prediction in cervical cancer using magnetic resonance imaging. Int J Radiat Oncol Biol Phys. 2002;52(1):14–22. https://doi.org/10.1016/s0360-3016(01)01808-9.

Article  PubMed  Google Scholar 

Lindegaard JC, Fokdal LU, Nielsen SK, Juul-Christensen J, Tanderup K. MRI-guided adaptive radiotherapy in locally advanced cervical cancer from a Nordic perspective. Acta Oncol. 2013;52(7):1510–9. https://doi.org/10.3109/0284186X.2013.818253.

Article  CAS  PubMed  Google Scholar 

Kirisits C, Lang S, Dimopoulos J, Berger D, Georg D, Pötter R. The Vienna applicator for combined intracavitary and interstitial brachytherapy of cervical cancer: design, application, treatment planning, and dosimetric results. Int J Radiat Oncol Biol Phys. 2006;65(2):624–30. https://doi.org/10.1016/j.ijrobp.2006.01.036.

Article  PubMed  Google Scholar 

Tanaka K, Umesaki N. Impact of three-dimensional (3D) ultrasonography and power doppler angiography in the management of cervical cancer. Eur J Gynaecol Oncol. 2010;31(1):10–7 (PMID: 20349774).

CAS  PubMed  Google Scholar 

Alcázar JL, Jurado M. Three-dimensional ultrasound for assessing women with gynecological cancer: a systematic review. Gynecol Oncol. 2011;120(3):340–6. https://doi.org/10.1016/j.ygyno.2010.10.023.

Article  PubMed  Google Scholar 

Komatsu M, Teraya N, Natsume T, Harada N, Takeda K, Hamamoto R. Clinical application of artificial intelligence in ultrasound imaging for oncology. JMA J. 2025;8(15):18–25. https://doi.org/10.31662/jmaj.2024-0203.

Article  PubMed  Google Scholar 

Beriwal S, Demanes DJ, Erickson B, Jones E, De Los Santos JF, Cormack RA, et al. American Brachytherapy Society consensus guidelines for interstitial brachytherapy for vaginal cancer. Brachytherapy. 2012;11(1):68–75. https://doi.org/10.1016/j.brachy.2011.06.008.

Article  PubMed  Google Scholar 

Manea E, Chitoran E, Rotaru V, Ionescu S, Luca D, Cirimbei C, et al. Integration of ultrasound in image-guided adaptive brachytherapy in cancer of the uterine cervix. Bioeng. 2024;11(5):506. https://doi.org/10.3390/bioengineering11050506.

Article  Google Scholar 

Comments (0)

No login
gif