Racial and Ethnic Patterns Observed in Inflammatory Bowel Disease Prevalence, Clinical Burden, and Healthcare Resource Utilization in the United States: Findings from an Administrative Claims Database

Lin D, Jin Y, Shao X, et al. Global, regional, and national burden of inflammatory bowel disease, 1990-2021: Insights from the global burden of disease 2021. Int J Colorectal Dis. 1990;39(1):139.

Article  Google Scholar 

Prevalence of inflammatory bowel disease among adults aged ≥18 years—United States, 2015. [Internet]. Centers for Disease Control and Prevention 2015 [cited October 21, 2025].

Lewis JD, Parlett LE, Jonsson Funk ML, et al. Incidence, prevalence, and racial and ethnic distribution of inflammatory bowel disease in the United States. Gastroenterology. 2023;165(5):1197-205.e2.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tan Z, Zhu S, Liu C, et al. Causal link between inflammatory bowel disease and fistula: evidence from Mendelian randomization study. J Clin Med. 2023. https://doi.org/10.3390/jcm12072482.

Article  PubMed  PubMed Central  Google Scholar 

Barberio B, Zamani M, Black CJ, Savarino EV, Ford AC. Prevalence of symptoms of anxiety and depression in patients with inflammatory bowel disease: a systematic review and meta-analysis. Lancet Gastroenterol Hepatol. 2021;6(5):359–70.

Article  PubMed  Google Scholar 

Häuser W, Moser G, Klose P, Mikocka-Walus A. Psychosocial issues in evidence-based guidelines on inflammatory bowel diseases: a review. World J Gastroenterol. 2014;20(13):3663–71.

Article  PubMed  PubMed Central  Google Scholar 

Byrne G, Rosenfeld G, Leung Y, et al. Prevalence of anxiety and depression in patients with inflammatory bowel disease. Can J Gastroenterol Hepatol. 2017;2017:6496727.

Article  PubMed  PubMed Central  Google Scholar 

Barnes EL, Loftus EV Jr, Kappelman MD. Effects of race and ethnicity on diagnosis and management of inflammatory bowel diseases. Gastroenterology. 2021;160(3):677–89.

Article  PubMed  Google Scholar 

Nguyen GC, LaVeist TA, Harris ML, et al. Racial disparities in utilization of specialist care and medications in inflammatory bowel disease. Am J Gastroenterol. 2010;105(10):2202–8.

Article  PubMed  PubMed Central  Google Scholar 

Nguyen GC, Torres EA, Regueiro M, et al. Inflammatory bowel disease characteristics among African Americans, Hispanics, and non-Hispanic Whites: characterization of a large North American cohort. Am J Gastroenterol. 2006;101(5):1012–23.

Article  PubMed  Google Scholar 

Cai Q, Ding Z, Fu AZ, Patel AA. Racial or ethnic differences on treatment adherence and persistence among patients with inflammatory bowel diseases initiated with biologic therapies. BMC Gastroenterol. 2022;22(1):545.

Article  PubMed  PubMed Central  Google Scholar 

Race and ethnicity data—helping bridge the gap in health equity. 2024. https://www.optum.com/en/business/insights/advisory-services/page.hub5.reporting-race-ethnicity-data-rwd.html.

Aniwan S, Santiago P, Loftus EV Jr, Park SH. The epidemiology of inflammatory bowel disease in Asia and Asian immigrants to Western countries. United Eur Gastroenterol J. 2022;10(10):1063–76.

Article  CAS  Google Scholar 

Park J, Cheon JH. Incidence and prevalence of inflammatory bowel disease across Asia. Yonsei Med J. 2021;62(2):99–108.

Article  PubMed  PubMed Central  Google Scholar 

Fan Y, Zhang L, Melmed GY. Prevalence, incidence, and treatment patterns of fistulizing Crohn disease: a US population-based cohort study. J Manag Care Spec Pharm. 2024;30(5):420–9.

PubMed  PubMed Central  Google Scholar 

Panés J, Rimola J. Perianal fistulizing Crohn’s disease: pathogenesis, diagnosis and therapy. Nat Rev Gastroenterol Hepatol. 2017;14(11):652–64.

Article  PubMed  Google Scholar 

Schwartz DA, Tagarro I, Carmen Díez M, Sandborn WJ. Prevalence of fistulizing Crohn’s disease in the United States: estimate from a systematic literature review attempt and population-based database analysis. Inflamm Bowel Dis. 2019;25(11):1773–9.

Article  PubMed  PubMed Central  Google Scholar 

Kilic Y, Kamal S, Jaffar F, et al. Prevalence of Extraintestinal Manifestations in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis. Inflamm Bowel Dis. 2024;30(2):230–9.

Article  PubMed  Google Scholar 

Gonczi L, Lakatos L, Golovics PA, et al. Burden of perianal disease in Crohn’s disease: accelerating medical therapy and high rates of perianal surgery over the last four decades—results from a population-based study over four decades. Aliment Pharmacol Ther. 2024;59(5):656–65.

Article  CAS  PubMed  Google Scholar 

Bonfils L, Karachalia Sandri A, Poulsen GJ, et al. Medication-wide study: exploring medication use 10 years before a diagnosis of inflammatory bowel disease. Am J Gastroenterol. 2023;118(12):2220–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cohen NA, Kliper E, Zamstein N, et al. Trends in biochemical parameters, healthcare resource and medication use in the 5 years preceding IBD diagnosis: a health maintenance organization cohort study. Dig Dis Sci. 2023;68(2):414–22.

Article  CAS  PubMed  Google Scholar 

Singh S, Qian AS, Nguyen NH, et al. Trends in U.S. health care spending on inflammatory bowel diseases, 1996-2016. Inflamm Bowel Dis. 1996;28(3):364–72.

Article  Google Scholar 

Ma C, Smith MK, Guizzetti L, et al. Assessing national trends and disparities in ambulatory, emergency department, and inpatient visits for inflammatory bowel disease in the United States (2005–2016). Clin Gastroenterol Hepatol. 2020;18(11):2500-9.e1.

Article  PubMed  PubMed Central  Google Scholar 

Rubin DT, Ananthakrishnan AN, Siegel CA, Sauer BG, Long MD. ACG clinical guideline: ulcerative colitis in adults. Am J Gastroenterol. 2019;114(3):384–413.

Article  PubMed  Google Scholar 

Lamb CA, Kennedy NA, Raine T, et al. British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults. Gut. 2019;68(Suppl 3):s1–106.

Article  PubMed  PubMed Central  Google Scholar 

Lutgens MW, Oldenburg B, Siersema PD, et al. Colonoscopic surveillance improves survival after colorectal cancer diagnosis in inflammatory bowel disease. Br J Cancer. 2009;101(10):1671–5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kim HS, Hernaez R, Sansgiry S, et al. Comparative effectiveness of surveillance colonoscopy intervals on colorectal cancer outcomes in a national cohort of patients with inflammatory bowel disease. Clin Gastroenterol Hepatol. 2022;20(12):2848-57.e2.

Article  PubMed  PubMed Central  Google Scholar 

Chavannes M, Dolinger MT, Cohen-Mekelburg S, Abraham B. AGA clinical practice update on the role of intestinal ultrasound in inflammatory bowel disease: commentary. Clin Gastroenterol Hepatol. 2024;22(9):1790-5.e1.

Article  PubMed  Google Scholar 

Bilican G, Karakan T, Eğritaş Gürkan Ö, et al. Intestinal ultrasound: advancing towards broader adoption—insights from a national survey in Turkey. J Clin Med. 2025;14(14):4817.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Graff LA, Walker JR, Bernstein CN. Depression and anxiety in inflammatory bowel disease: a review of comorbidity and management. Inflamm Bowel Dis. 2009;15(7):1105–18.

Article  PubMed  Google Scholar 

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