Sun, H., P. Saeedi, S. Karuranga, M. Pinkepank, K. Ogurtsova, B.B. Duncan, C. Stein, A. Basit, J.C.N. Chan, J.C. Mbanya, et al. 2022. IDF Diabetes atlas: global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045. Diabetes Research and Clinical Practice 183: 109119.

Article  PubMed  Google Scholar 

Greenlee, M.C., S. Bolen, W. Chong, A. Dokun, J. Gonzalvo, M. Hawkins, W.H. Herman, E. Leake, B. Linder, and P.R. Conlin. 2023. The national clinical care commission report to congress: leveraging federal policies and programs to improve diabetes treatment and reduce complications. Diabetes Care 46 (2): 51–59.

Article  Google Scholar 

Pop-Busui, R., J.L. Januzzi, D. Bruemmer, S. Butalia, J.B. Green, W.B. Horton, C. Knight, M. Levi, N. Rasouli, and C.R. Richardson. 2022. Heart failure: an underappreciated complication of diabetes. A consensus report of the american diabetes association. Diabetes Care 45 (7): 1670–1690.

Article  PubMed  PubMed Central  Google Scholar 

Tan, Y., Z. Zhang, C. Zheng, K.A. Wintergerst, B.B. Keller, and L. Cai. 2020. Mechanisms of diabetic cardiomyopathy and potential therapeutic strategies: Preclinical and clinical evidence. Nature Reviews Cardiology 17 (9): 585–607.

Article  PubMed  PubMed Central  Google Scholar 

Ritchie, R.H., and E.D. Abel. 2020. Basic mechanisms of diabetic heart disease. Circulation Research 126 (11): 1501–1525.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ramesh, P., J.L. Yeo, E.M. Brady, and G.P. McCann. 2022. Role of inflammation in diabetic cardiomyopathy. Therapeutic Advances in Endocrinology and Metabolism 13: 20420188221083530.

Article  PubMed  PubMed Central  Google Scholar 

Mao, X., B. Yan, H. Chen, P. Lai, and J. Ma. 2023. BRG1 mediates protective ability of spermidine to ameliorate osteoarthritic cartilage by Nrf2/KEAP1 and STAT3 signaling pathway. International Immunopharmacology 122: 110593.

Article  CAS  PubMed  Google Scholar 

Guo, K., Y. Shang, Z. Wang, Y. Li, J. Chen, B. Zhu, D. Zhang, and J. Chen. 2012. BRG1 alleviates microglial activation by promoting the KEAP1-NRF2/HO-1 signaling pathway and minimizing oxidative damage in cerebral ischemia–reperfusion. International Immunopharmacology 119: 110201.

Article  Google Scholar 

Hang, C.T., J. Yang, P. Han, H.-L. Cheng, C. Shang, E. Ashley, B. Zhou, and C.-P. Chang. 2010. Chromatin regulation by Brg1 underlies heart muscle development and disease. Nature 466 (7302): 62–67.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu, X., X. Yuan, G. Liang, S. Zhang, G. Zhang, Y. Qin, Q. Zhu, Q. Xiao, and N. Hou. 2020. Luo J-d: BRG1 protects the heart from acute myocardial infarction by reducing oxidative damage through the activation of the NRF2/HO1 signaling pathway. Free Radical Biology and Medicine 160: 820–836.

Article  CAS  PubMed  Google Scholar 

Li, H., W. Yao, M.G. Irwin, T. Wang, S. Wang, L. Zhang, and Z. Xia. 2015. Adiponectin ameliorates hyperglycemia-induced cardiac hypertrophy and dysfunction by concomitantly activating Nrf2 and Brg1. Free Radical Biology and Medicine 84: 311–321.

Article  CAS  PubMed  Google Scholar 

Qi, W., R. Wang, H. Chen, X. Wang, T. Xiao, I. Boldogh, X. Ba, L. Han, and X. Zeng. 2015. BRG1 promotes the repair of DNA double-strand breaks by facilitating the replacement of RPA with RAD51. Journal of Cell Science 128 (2): 317–330.

CAS  PubMed  PubMed Central  Google Scholar 

Han, X., H. Chen, H. Gong, X. Tang, N. Huang, W. Xu, H. Tai, G. Zhang, T. Zhao, C. Gong, et al. 2020. Autolysosomal degradation of cytosolic chromatin fragments antagonizes oxidative stress–induced senescence. Journal of Biological Chemistry 295 (14): 4451–4463.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Decout, A., J.D. Katz, S. Venkatraman, and A. Ablasser. 2021. The cGAS–STING pathway as a therapeutic target in inflammatory diseases. Nature Reviews Immunology 21 (9): 548–569.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Skopelja-Gardner, S., J. An, and K.B. Elkon. 2022. Role of the cGAS–STING pathway in systemic and organ-specific diseases. Nature Reviews Nephrology 18 (9): 558–572.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ma, X.M., and K. Geng. 2022. Law BY-K, Wang P, Pu YL, Chen Q, Xu HW, Tan XZ, Jiang ZZ, Xu Y: Lipotoxicity-induced mtDNA release promotes diabetic cardiomyopathy by activating the cGAS-STING pathway in obesity-related diabetes. Cell Biology and Toxicology 39 (1): 277–299.

Article  PubMed  PubMed Central  Google Scholar 

Yan, M., Y. Li, Q. Luo, W. Zeng, X. Shao, L. Li, Q. Wang, D. Wang, Y. Zhang, H. Diao, et al. 2022. Mitochondrial damage and activation of the cytosolic DNA sensor cGAS–STING pathway lead to cardiac pyroptosis and hypertrophy in diabetic cardiomyopathy mice. Cell Death Discovery 8 (1): 258.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hou, N., B. Cai, C.-W. Ou, Z.-H. Zhang, X.-W. Liu, M. Yuan, G.-J. Zhao, S.-M. Liu, L.-G. Xiong, J.-D. Luo, et al. 2017. Puerarin-7-O-glucuronide, a water-soluble puerarin metabolite, prevents angiotensin II-induced cardiomyocyte hypertrophy by reducing oxidative stress. Naunyn-Schmiedeberg’s Archives of Pharmacology 390 (5): 535–545.

Article  CAS  PubMed  Google Scholar 

Dhar, A., J. Venkadakrishnan, U. Roy, S. Vedam, N. Lalwani, K.S. Ramos, T.K. Pandita, and A. Bhat. 2023. A comprehensive review of the novel therapeutic targets for the treatment of diabetic cardiomyopathy. Therapeutic Advances in Cardiovascular Disease 17: 17539447231210170.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Paolillo, S., F. Marsico, M. Prastaro, F. Renga, L. Esposito, F. De Martino, P. Di Napoli, I. Esposito, A. Ambrosio, M. Ianniruberto, et al. 2019. Diabetic cardiomyopathy: definition, diagnosis, and therapeutic implications. Heart Failure Clinics 15 (3): 341–347.

Article  PubMed  Google Scholar 

Zhang, L., H. Zhang, X. Xie, R. Tie, X. Shang, Q. Zhao, J. Xu, L. Jin, J. Zhang, and P. Ye. 2023. Empagliflozin ameliorates diabetic cardiomyopathy via regulated branched-chain amino acid metabolism and mTOR/p-ULK1 signaling pathway-mediated autophagy. Diabetology and Metabolic Syndrome 15 (1): 93.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pham, T.K., T.H.T. Nguyen, J.M. Yi, G.S. Kim, H.R. Yun, H.K. Kim, and J.C. Won. 2023. Evogliptin, a DPP-4 inhibitor, prevents diabetic cardiomyopathy by alleviating cardiac lipotoxicity in db/db mice. Experimental and Molecular Medicine 55 (4): 767–778.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ma, Z.-Y., J. Li, X.-H. Dong, Y.-T. Cui, Y.-F. Cui, T. Ban, and R. Huo. 2023. The role of BRG1 in epigenetic regulation of cardiovascular diseases. European Journal of Pharmacology 957: 176039.

Article  CAS  PubMed  Google Scholar 

Lin, H., Y. Zhu, C. Zheng, D. Hu, S. Ma, L. Chen, Q. Wang, Z. Chen, J. Xie, Y. Yan, et al. 2021. Antihypertrophic memory after regression of exercise-induced physiological myocardial hypertrophy is mediated by the long noncoding RNA Mhrt779. Circulation 143 (23): 2277–2292.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Funamoto, M., Y. Sunagawa, Y. Katanasaka, K. Shimizu, Y. Miyazaki, N. Sari, S. Shimizu, K. Mori, H. Wada, K. Hasegawa, et al. 2021. Histone acetylation domains are differentially induced during development of heart failure in dahl salt-sensitive rats. International Journal of Molecular Sciences 22 (4): 1771.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang, Y., H. Wang, M. Song, T. Xu, X. Chen, T. Li, and T. Wu. 2020. Brahma-related gene 1 deficiency in endothelial cells ameliorates vascular inflammatory responses in mice. Frontiers in Cell and Developmental Biology 8: 578790.

Article  PubMed  PubMed Central  Google Scholar 

Yang Yuan, C.W. 2014. Jibin Xu, Jin Tao, Zhiyun Xu, Shengdong Huang: BRG1 overexpression in smooth muscle cells promotes the development of thoracic aortic dissection. BMC Cardiovascular Disorders 14: 144.

Article  PubMed  PubMed Central  Google Scholar 

Li, Z., X. Zhang, S. Liu, S. Zeng, L. Yu, G. Yang, J. Guo, and Y. Xu. 2018. BRG1 regulates NOX gene transcription in endothelial cells and contributes to cardiac ischemia-reperfusion injury. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1864 (10): 3477–3486.

Article  CAS