Wang, H. et al. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet 388, 1459–1544 (2016).
Arranja, A. G. et al. Tumor-targeted nanomedicines for cancer theranostics. Pharmacol. Res. 115, 87–95 (2017).
Zhou, S. et al. Tumour-targeting bacteria engineered to fight cancer. Nat. Rev. Cancer 18, 727–743 (2018).
CAS PubMed PubMed Central Google Scholar
Yi, X. et al. Bacteria-triggered tumor-specific thrombosis to enable potent photothermal immunotherapy of cancer. Sci. Adv. 6, eaba3546 (2020).
CAS PubMed PubMed Central Google Scholar
Chen, Y. et al. Genetically engineered oncolytic bacteria as drug delivery systems for targeted cancer theranostics. Acta Biomater. 124, 72–87 (2021).
Kim, S. H. et al. High efficacy of a Listeria-based vaccine against metastatic breast cancer reveals a dual mode of action. Cancer Res. 69, 5860–5866 (2009).
CAS PubMed PubMed Central Google Scholar
Pan, H. et al. Engineered NIR light-responsive bacteria as anti-tumor agent for targeted and precise cancer therapy. Chem. Eng. J. 426, 130842 (2021).
Zheng, J. H. et al. Two-step enhanced cancer immunotherapy with engineered Salmonella typhimurium secreting heterologous flagellin. Sci. Transl. Med. 9, eaak9537 (2017).
Chen, Y. et al. Spatiotemporal control of engineered bacteria to express interferon-γ by focused ultrasound for tumor immunotherapy. Nat. Commun. 13, 4468 (2022).
CAS PubMed PubMed Central Google Scholar
Chait, R. et al. Pervasive selection for and against antibiotic resistance in inhomogeneous multistress environments. Nat. Commun. 7, 10333 (2016).
CAS PubMed PubMed Central Google Scholar
Gao, T. et al. Sonogenetics-controlled synthetic designer cells for cancer therapy in tumor mouse models. Cell Rep. Med. 5, 101513 (2024).
CAS PubMed PubMed Central Google Scholar
Lim, J. et al. ASIC1a is required for neuronal activation via low-intensity ultrasound stimulation in mouse brain. eLife 10, e61660 (2021).
CAS PubMed PubMed Central Google Scholar
Yang, F. et al. Principles and applications of sono-optogenetics. Adv. Drug Deliv. Rev. 194, 114711 (2023).
CAS PubMed PubMed Central Google Scholar
Chen, X. et al. An extraordinary stringent and sensitive light-switchable gene expression system for bacterial cells. Cell Res. 26, 854–857 (2016).
PubMed PubMed Central Google Scholar
Ribeiro, I. M. A. et al. Spatial and temporal control of expression with light-gated LOV-LexA. G3 12, jkac178 (2022).
CAS PubMed PubMed Central Google Scholar
Wang, Z. et al. A single-component blue light-induced system based on EL222 in Yarrowia lipolytica. Int. J. Mol. Sci. 23, 6344 (2022).
CAS PubMed PubMed Central Google Scholar
Tan, P. et al. Optophysiology: illuminating cell physiology with optogenetics. Physiol. Rev. 102, 1263–1325 (2022).
CAS PubMed PubMed Central Google Scholar
Weissleder, R. A clearer vision for in vivo imaging: progress continues in the development of smaller, more penetrable probes for biological imaging. Nat. Biotechnol. 19, 316–317 (2001).
Schmidl, S. R. et al. Refactoring and optimization of light-switchable Escherichia coli two-component systems. ACS Synth. Biol. 3, 820–831 (2014).
Kaberniuk, A. A. et al. Single-component near-infrared optogenetic systems for gene transcription regulation. Nat. Commun. 12, 3859 (2021).
CAS PubMed PubMed Central Google Scholar
Multamäki, E. et al. Optogenetic control of bacterial expression by red light. ACS Synth. Biol. 11, 3354–3367 (2022).
PubMed PubMed Central Google Scholar
Ong, N. T. et al. Engineering an E. coli near-infrared light sensor. ACS Synth. Biol. 7, 240–248 (2018).
Gnach, A. et al. Upconverting nanoparticles: assessing the toxicity. Chem. Soc. Rev. 44, 1561–1584 (2015).
Gourinchas, G. et al. Influence of the N-terminal segment and the PHY-tongue element on light-regulation in bacteriophytochromes. J. Biol. Chem. 294, 4498–4510 (2019).
CAS PubMed PubMed Central Google Scholar
Wegele, R. et al. The heme oxygenase(s)-phytochrome system of Pseudomonas aeruginosa. J. Biol. Chem. 279, 45791–45802 (2004).
Wilksch, J. J. et al. MrkH, a novel c-di-GMP-dependent transcriptional activator, controls Klebsiella pneumoniae biofilm formation by regulating type 3 fimbriae expression. PLoS Pathog. 7, e1002204 (2011).
CAS PubMed PubMed Central Google Scholar
Ryu, M. H. & Gomelsky, M. Near-infrared light responsive synthetic c-di-GMP module for optogenetic applications. ACS Synth. Biol. 3, 802–810 (2014).
CAS PubMed PubMed Central Google Scholar
Solano, C. et al. Genetic analysis of Salmonella enteritidis biofilm formation: critical role of cellulose. Mol. Microbiol. 43, 793–808 (2002).
Solano, C. et al. Genetic reductionist approach for dissecting individual roles of GGDEF proteins within the c-di-GMP signaling network in Salmonella. Proc. Natl Acad. Sci. USA 106, 7997–8002 (2009).
CAS PubMed PubMed Central Google Scholar
Lovelace, A. H. et al. RpoS contributes in a host-dependent manner to Salmonella colonization of the leaf apoplast during plant disease. Front. Microbiol. 13, 999183 (2022).
PubMed PubMed Central Google Scholar
Kim, J. K. et al. Purine biosynthesis-deficient Burkholderia mutants are incapable of symbiotic accommodation in the stinkbug. ISME J. 8, 552–563 (2014).
Howe, K. et al. Development of stable reporter system cloning luxCDABE genes into chromosome of Salmonella enterica serotypes using Tn7 transposon. BMC Microbiol. 10, 197 (2010).
PubMed PubMed Central Google Scholar
Danino, T. et al. Programmable probiotics for detection of cancer in urine. Sci. Transl. Med. 7, 289ra284 (2015).
McKenzie, G. J. & Craig, N. L. Fast, easy and efficient: site-specific insertion of transgenes into enterobacterial chromosomes using Tn7 without need for selection of the insertion event. BMC Microbiol. 6, 39 (2006).
PubMed PubMed Central Google Scholar
Kalbasi, A. & Ribas, A. Tumour-intrinsic resistance to immune checkpoint blockade. Nat. Rev. Immunol. 20, 25–39 (2020).
Chen, D. S. & Mellman, I. Elements of cancer immunity and the cancer-immune set point. Nature 541, 321–330 (2017).
Gurbatri, C. R. et al. Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies. Sci. Transl. Med. 12, 1 (2020).
Sandage, B. W. et al. Abstract 2619: combination of ECP1014 and anti-PD-L1 reduces tumor growth in the CT26 murine colon carcinoma model of a cold tumor. Cancer Res. 77, 2619–2619 (2017).
Zhang, Y. et al. Escherichia coli Nissle 1917 targets and restrains mouse B16 melanoma and 4T1 breast tumors through expression of azurin protein. Appl. Environ. Microbiol. 78, 7603–7610 (2012).
Comments (0)