Laumont CM, Nelson BH. B cells in the tumor microenvironment: multi-faceted organizers, regulators, and effectors of anti-tumor immunity. Cancer Cell. 2023;41(3):466–89. https://doi.org/10.1016/j.ccell.2023.02.017.

Article  CAS  PubMed  Google Scholar 

Nemazee D. Mechanisms of central tolerance for B cells. Nat Rev Immunol. 2017;17(5):281–94. https://doi.org/10.1038/nri.2017.19.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brink R, Phan TG. Self-reactive B cells in the germinal center reaction. Annu Rev Immunol. 2018;36:339–57. https://doi.org/10.1146/annurev-immunol-051116-052510.

Article  CAS  PubMed  Google Scholar 

Xiao ZX, Miller JS, Zheng SG. An updated advance of autoantibodies in autoimmune diseases. Autoimmun Rev. 2021;20(2):102743. https://doi.org/10.1016/j.autrev.2020.102743.

Article  CAS  PubMed  Google Scholar 

Dorner T, Giesecke C, Lipsky PE. Mechanisms of B cell autoimmunity in SLE. Arthritis Res Ther. 2011;13(5):243. https://doi.org/10.1186/ar3433.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mattoo H, Mahajan VS, Della-Torre E, Sekigami Y, Carruthers M, Wallace ZS, et al. De novo oligoclonal expansions of circulating plasmablasts in active and relapsing IgG4-related disease. J Allergy Clin Immunol. 2014;134(3):679–87. https://doi.org/10.1016/j.jaci.2014.03.034.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tout I, Miossec P. The role of B cells and their interactions with stromal cells in the context of inflammatory autoimmune diseases. Autoimmun Rev. 2022;21(6):103098. https://doi.org/10.1016/j.autrev.2022.103098.

Article  CAS  PubMed  Google Scholar 

Cheng J, Liu Y, Yan J, Zhao L, Zhou Y, Shen X, et al. Fumarate suppresses B-cell activation and function through direct inactivation of LYN. Nat Chem Biol. 2022;18(9):954–62. https://doi.org/10.1038/s41589-022-01052-0.

Article  CAS  PubMed  Google Scholar 

Chang CH, Curtis JD, Maggi LB Jr, Faubert B, Villarino AV, O’Sullivan D, et al. Posttranscriptional control of T cell effector function by aerobic glycolysis. Cell. 2013;153(6):1239–51. https://doi.org/10.1016/j.cell.2013.05.016.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sharma R, Smolkin RM, Chowdhury P, Fernandez KC, Kim Y, Cols M, et al. Distinct metabolic requirements regulate B cell activation and germinal center responses. Nat Immunol. 2023;24(8):1358–69. https://doi.org/10.1038/s41590-023-01540-y.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yu A, Yu P, Zhu Y, Zhu R, Sun R, Ye D, Yu FX. Glucose-induced and chrebp: mlx-mediated lipogenic program promotes hepatocellular carcinoma development. Oncogene. 2023;42(43):3182–93. https://doi.org/10.1038/s41388-023-02831-2.

Article  CAS  PubMed  Google Scholar 

Wang JY. B cells in immunity and tolerance. Singapore: Springer; 2020.

Book  Google Scholar 

Tonegawa S. Molecular biology of immunologic recognition. Tanpakushitsu Kakusan Koso. 1987;32(3):239–50.

CAS  PubMed  Google Scholar 

Arvidsson G, Czarnewski P, Johansson A, Raine A, Imgenberg-Kreuz J, Nordlund J, et al. Multimodal single-cell sequencing of B cells in primary Sjogren’s syndrome. Arthritis Rheumatol. 2024;76(2):255–67. https://doi.org/10.1002/art.42683.

Article  CAS  PubMed  Google Scholar 

Liu Y, Fan R, Zhou S, Yu Z, Zhang Z. Potential contribution of Vh gene replacement in immunity and disease. Ann N Y Acad Sci. 2005;1062:175–81. https://doi.org/10.1196/annals.1358.020.

Article  PubMed  Google Scholar 

Wang JJ, Reed JH, Colella AD, Russell AJ, Murray-Brown W, Chataway TK, et al. Molecular profiling and clonal tracking of secreted rheumatoid factors in primary Sjogren’s syndrome. Arthritis Rheumatol. 2018;70(10):1617–25. https://doi.org/10.1002/art.40539.

Article  CAS  PubMed  Google Scholar 

Allman D, Lindsley RC, DeMuth W, Rudd K, Shinton SA, Hardy RR. Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation. J Immunol. 2001;167(12):6834–40. https://doi.org/10.4049/jimmunol.167.12.6834.

Article  CAS  PubMed  Google Scholar 

Pieper K, Grimbacher B, Eibel H. B-cell biology and development. J Allergy Clin Immunol. 2013;131(4):959–71. https://doi.org/10.1016/j.jaci.2013.01.046.

Article  CAS  PubMed  Google Scholar 

Korzhenevich J, Janowska I, van der Burg M, Rizzi M. Human and mouse early B cell development: so similar but so different. Immunol Lett. 2023;261:1–12. https://doi.org/10.1016/j.imlet.2023.07.004.

Article  CAS  PubMed  Google Scholar 

Cerutti A, Cols M, Puga I. Marginal zone B cells: virtues of innate-like antibody-producing lymphocytes. Nat Rev Immunol. 2013;13(2):118–32. https://doi.org/10.1038/nri3383.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cyster JG, Allen CDC. B cell responses: cell interaction dynamics and decisions. Cell. 2019;177(3):524–40. https://doi.org/10.1016/j.cell.2019.03.016.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hoffman W, Lakkis FG, Chalasani G. B Cells, Antibodies, and More. Clin J Am Soc Nephrol. 2016;11(1):137–54. https://doi.org/10.2215/CJN.09430915.

Article  CAS  PubMed  Google Scholar 

Pillai S, Cariappa A, Moran ST. Marginal zone B cells. Annu Rev Immunol. 2005;23:161–96. https://doi.org/10.1146/annurev.immunol.23.021704.115728.

Article  CAS  PubMed  Google Scholar 

Scheeren FA, Nagasawa M, Weijer K, Cupedo T, Kirberg J, Legrand N, Spits H. T cell-independent development and induction of somatic hypermutation in human IgM+ IgD+ CD27+ B cells. J Exp Med. 2008;205(9):2033–42. https://doi.org/10.1084/jem.20070447.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Babushku T, Lechner M, Ehrenberg S, Rambold U, Schmidt-Supprian M, Yates AJ, et al. Notch2 controls developmental fate choices between germinal center and marginal zone B cells upon immunization. Nat Commun. 2024;15(1):1960. https://doi.org/10.1038/s41467-024-46024-1.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lechner M, Engleitner T, Babushku T, Schmidt-Supprian M, Rad R, Strobl LJ, Zimber-Strobl U. Notch2-mediated plasticity between marginal zone and follicular B cells. Nat Commun. 2021;12(1):1111. https://doi.org/10.1038/s41467-021-21359-1.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mebius RE, Kraal G. Structure and function of the spleen. Nat Rev Immunol. 2005;5(8):606–16. https://doi.org/10.1038/nri1669.

Article  CAS  PubMed  Google Scholar 

Henderson RB, Grys K, Vehlow A, de Bettignies C, Zachacz A, Henley T, et al. A novel Rac-dependent checkpoint in B cell development controls entry into the splenic white pulp and cell survival. J Exp Med. 2010;207(4):837–53. https://doi.org/10.1084/jem.20091489.

Article  CAS