Akhtar G, Shabbir A (2019) Urginea indica attenuated rheumatoid arthritis and inflammatory paw edema in diverse animal models of acute and chronic inflammation. J Ethnopharmacol 238:111864. https://doi.org/10.1016/jjep2019111864

Article  CAS  PubMed  Google Scholar 

Akhtar MF, Khan K, Saleem A, Baig MFA, Rasul A, Abdel-Daim MM (2021) Chemical characterization and anti-arthritic appraisal of Monotheca buxifolia methanolic extract in complete Freund’s adjuvant-induced arthritis in Wistar rats. Inflammopharmacology 29:393–408. https://doi.org/10.1007/s10787-020-00783-7

Article  CAS  PubMed  Google Scholar 

Aletaha D, Smolen JS (2018) Diagnosis and management of rheumatoid arthritis: a review. Je Am Med Assoc 320:1360–1372. https://doi.org/10.1001/jama201813103

Article  Google Scholar 

Almatroodi SA, Almatroudi A, Alharbi HA, Khan AA, Rahmani AH (2024) Effects and mechanisms of luteolin a plant-based flavonoid in the prevention of cancers via modulation of inflammation and cell signaling molecules. Molecules 29:1093. https://doi.org/10.3390/molecules29051093

Article  CAS  PubMed  PubMed Central  Google Scholar 

Aloke C, Ibiam UA, Orji OU, Ugwuja EI, Ezeani NN, Aja PM, Obasi NA (2021) Anti-arthritic potential of ethanol and aqueous extracts of stem bark of Cleistopholis patens on complete Freund’s adjuvant-induced rheumatoid arthritis in rats. J Ayurveda Integr Med 12:28–34. https://doi.org/10.1016/j.jaim.2018.12.009

Article  CAS  PubMed  Google Scholar 

Amraoui N, Mayouf N, Charef N, Baghiani A, Arrar L (2019) Antioxidant anti-inflammatory and anti-arthritic activities of methanol extract of Tamus communis L roots. Trop J Pharm Res 18:1499–1506. https://doi.org/10.4314/tjpr.v18i7.20

Article  CAS  Google Scholar 

Bullock J, Rizvi SA, Saleh AM, Ahmed SS, Do DP, Ansari RA, Ahmed J (2018) Rheumatoid arthritis: a brief overview of the treatment. Med Princ Pract 27:501–507. https://doi.org/10.1159/000493390

Article  PubMed  PubMed Central  Google Scholar 

Cárdeno A, Aparicio-Soto M, Montserrat-de la Paz S, Bermúdez B, Muriana FJ, Alarcón-de-la-Lastra C (2015) Squalene targets pro-and anti-inflammatory mediators and pathways to modulate over-activation of neutrophils monocytes and macrophages. J Funct Foods 14:779–790. https://doi.org/10.1016/j.jff.2015.03.009

Article  CAS  Google Scholar 

Cheng L, Chen J, Rong X (2022) Mechanism of emodin in the treatment of rheumatoid arthritis. Evid Based Complementary Alternat Med 2022:9482570. https://doi.org/10.1155/2022/9482570

Article  Google Scholar 

Cui X, Wang R, Bian P, Wu Q, Seshadri VD, Liu L (2019) Evaluation of antiarthritic activity of nimbolide against Freund’s adjuvant induced arthritis in rats artificial cells. Nanomed Biotechnol 47:3391–3398. https://doi.org/10.1080/21691401.-2019.1649269

Article  CAS  Google Scholar 

Dai Y, Wang W, Yu Y, Hu S (2021) Rheumatoid arthritis–associated interstitial lung disease: an overview of epidemiology pathogenesis and management. Clin Rheumatol 40:1211–1220. https://doi.org/10.1007/s10067-020-05320-z

Article  PubMed  Google Scholar 

Dave AR, Pillai PP (2024) Anti-inflammatory effects of quercetin in lipopolysaccharide-activated cortical astrocytes. Brain Behav Immunity Integr 8:100095. https://doi.org/10.1016/j.bbii.2024.100095

Article  Google Scholar 

Dong C, Fu T, Ji J, Li Z, Gu Z (2018) The role of interleukin-4 in rheumatic diseases. Clin Exp Pharmacol Physiol 45:747–754. https://doi.org/10.1111/1440-1681.12946

Article  CAS  PubMed  Google Scholar 

Dringen R, Gutterer JM (2002) Glutathione reductase from bovine brain. Methods Enzymol 348:281–288. https://doi.org/10.1016/S0076-6879(02)48646-6

Article  CAS  PubMed  Google Scholar 

Edilova MI, Akram A, Abdul-Sater AA (2021) Innate immunity drives pathogenesis of rheumatoid arthritis. Biomed J 44:172–182. https://doi.org/10.1016/j.bj.-2020.06.010

Article  CAS  PubMed  Google Scholar 

Favalli EG (2020) Understanding the role of interleukin-6 (IL-6) in the joint and beyond: a comprehensive review of IL-6 inhibition for the management of rheumatoid arthritis. Rheumatology and Therapy 7:473–517. https://doi.org/10.1007/s40744-020-00219-2

Article  PubMed  PubMed Central  Google Scholar 

Goel A, Kulshrestha S (2021) Review on anti-rheumatoid arthritis potential of medicinal plants. Int J Current Res Rev 13:16–32. https://doi.org/10.31782/IJCRR.2021.13303

Article  CAS  Google Scholar 

Gonzal TE, Flore DS, Donatien AA, William NY, Herve TT, Vanessa MM, Marius M, Gilbert A (2020) In vitro anti-inflammatory anti-oxidant and in vivo anti-arthritic properties of stem bark extracts from Nauclea pobeguinii (Rubiaceae) in rats. Asian Pac J Trop Biomed 10:65–67. https://doi.org/10.4103/2221-1691.275421

Article  CAS  Google Scholar 

Gou KJ, Zeng R, Ren XD, Dou QL, Yang QB, Dong Y, Qu Y (2018) Anti-rheumatoid arthritis effects in adjuvant-induced arthritis in rats and molecular docking studies of Polygonum orientale L extracts. Immunol Lett 201:59–69. https://doi.org/10.1016/j.imlet.2018.11.009

Article  CAS  PubMed  Google Scholar 

Hadwan MH, Almashhedy LA, Alsalman AS (2013) Precise method for the assessment of catalase-like activity in seminal fluids. Int J Pharm Bio Sci 4(1):949–954. https://doi.org/10.1485/ijst/2016/v9i4/80499

Article  Google Scholar 

Hamed A, Mantawy E, El-Bakly W, Abdel-Mottaleb Y, Azab S (2020) Methyl palmitate: the naturally occurring cardioprotective agent. Arch Pharm Sci Ain Shams Univ 4:47–62. https://doi.org/10.21608/APS.2020.2003.1026

Article  Google Scholar 

Honmore VS, Kandhare AD, Kadam P, Khedkar VM, Natu AD, Rojatka SR, Bodhankar SL (2019) Diarylheptanoid a constituent isolated from methanol extract of Alpinia officinarum attenuates TNF-α level in Freund’s complete adjuvant-induced arthritis in rats. J Ethnopharmacol 229:233–245. https://doi.org/10.1016/j.jep.2018.10.019

Article  CAS  PubMed  Google Scholar 

Hussain MS, Altamimi ASA, Afzal M, Almalki WH, Kazmi I, Alzarea SI, Subramaniyan V (2024) Kaempferol: paving the path for advanced treatments in aging-related diseases. Exp Gerontol 188:112389. https://doi.org/10.1016/j.exger.2024.112389

Article  CAS  PubMed  Google Scholar 

Kamal RM, Sabry MM, Aly ZY, Hifnawy MS (2021) Phytochemical and in-vivo anti-arthritic significance of aloe thraskii baker in combined therapy with methotrexate in adjuvant-induced arthritis in rats. Molecules 26:3660. https://doi.org/10.3390/molecules26123660

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kamel KM, Gad AM, Mansour SM, Safar MM, Fawzy HM (2018) Novel anti-arthritic mechanisms of Polydatin in complete Freund’s adjuvant-induced arthritis in rats: involvement of IL-6 STAT-3 IL-17 and NF-кB. Inflammation 41:1974–1986. https://doi.org/10.1007/s10753-018-0841-4

Article  CAS  PubMed  Google Scholar 

Kiely PD, Nikiphorou E (2018) Management of rheumatoid arthritis. Medicine 46:216–221. https://doi.org/10.1016/j.mpmed.2018.01.006

Article  Google Scholar 

Kronzer VL, Davis JM (2021) Etiologies of rheumatoid arthritis: update on mucosal genetic and cellular pathogenesis. Curr Rheumatol Rep 23:1–10. https://doi.org/10.1007/s11926-021-00993-0

Article  CAS  Google Scholar 

Kshirsagar AD, Panchal PV, Harle UN, Shaikh NRK (2014) Anti-inflammatory and antiarthritic activity of anthraquinone derivatives in rodents. Int J Inflamm 2014:690596. https://doi.org/10.1155/2014/690596

Article  Google Scholar 

Larbi KS, Meddah B, Belkhodja H, Belmimoun A, Slimani K, Sonnet P (2017) Chemical composition and anti-arthritic activity of Anacyclus valentinus extract on adjuvant-induced arthritis in rats. Int J Environ Agric Biotechnol 2:238995. https://doi.org/10.22161/ijeab/2.6.31

Article  Google Scholar 

Lee CH, Choi EY (2018) Macrophages and inflammation. J Rheumat Dis 25:11–18. https://doi.org/10.4078/jrd.2018.25.1.11

Article  Google Scholar 

Li X, Xie Y, Kang A, Wang Y (2021) New bitongling (NBTL) ameliorates rheumatoid arthritis in rats through inhibiting JAK2/STAT3 signaling pathway. Eur J Histochem 65:3202. https://doi.org/10.4081/ejh.2021.3202

Article  CAS  PubMed