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Arbutin mediated neuroprotection in zebrafish model of traumatic brain injury via modulating Nrf2/NF-κB pathway
Arbutin mediated neuroprotection in zebrafish model of traumatic brain injury via modulating Nrf2/NF-κB pathway
Traumatic Brain Injury (TBI) is a major cause of mortality and disability worldwide and is associated with oxidative stres...
Correction to: Anti-inflammatory potential of C. DC., a promising piper species of North East India: and evidence and mechanistic insight
Correction to: Anti-inflammatory potential of C. DC., a promising piper species of North East India: and evidence and mechanistic insight
Cite this articleLoying, R., Sharmah, B., Barman, H. et al. Correction to: Anti-inflammatory potential of Piper betleoides...
Rutin as a multi-target anti-inflammatory phytochemical in arthritic disorders: pharmacological mechanisms and therapeutic potential
Rutin as a multi-target anti-inflammatory phytochemical in arthritic disorders: pharmacological mechanisms and therapeutic potential
Rutin, a bioactive flavonoid widely present in medicinal plants such as Fagopyrum esculentum, Ruta graveolens, and citrus ...
L derived phytochemicals mitigate acetic acid induced colitis in rats via orchestrating Nrf2/Keap1 signalling and LncRNAs gene expression
L derived phytochemicals mitigate acetic acid induced colitis in rats via orchestrating Nrf2/Keap1 signalling and LncRNAs gene expression
This study is the first to elucidate the mechanistic actions of Atriplex portulacoides L. methanolic extract (APME) as a n...
Valorization of 2-aminoethoxydiphenyl borate as a neurotherapeutic agent: modulation of calcineurin, TRPC1 and MARK2/GSK-3β signaling in scopolamine-triggered tauopathy
Valorization of 2-aminoethoxydiphenyl borate as a neurotherapeutic agent: modulation of calcineurin, TRPC1 and MARK2/GSK-3β signaling in scopolamine-triggered tauopathy
In Alzheimer’s disease (AD), amyloid beta (Aβ) plaques and hyperphosphorylated tau tangles drive neurodegenerat...
Ultra-deformable transethosomal vesicle for enhancing transdermal delivery of NSAIDs: a comprehensive review
Ultra-deformable transethosomal vesicle for enhancing transdermal delivery of NSAIDs: a comprehensive review
Topical and transdermal drug delivery methods provide an enticing option to conventional oral administration of non-steroi...
Chestnut ( Mill.) leaf extract and pure castalagin reduce bacterial colonisation and the associated inflammation in gastric organoids and a mouse model of infection
Chestnut ( Mill.) leaf extract and pure castalagin reduce bacterial colonisation and the associated inflammation in gastric organoids and a mouse model of infection
Helicobacter pylori is a bacterium that has been identified as a causative agent in the development of chronic gastritis, ...
Effects of curcumin on inflammatory and oxidative stress related markers in rat models of experimental arthritis: a systematic review and meta-analysis
Effects of curcumin on inflammatory and oxidative stress related markers in rat models of experimental arthritis: a systematic review and meta-analysis
This study evaluated whether orally administered pure curcumin affects inflammatory cytokines and oxidative stress-related...
From xanthine oxidase inhibition to inflammasome regulation: exploring the potential role of allopurinol in TXNIP–NLRP3 signaling and pyroptosis in diabetes
From xanthine oxidase inhibition to inflammasome regulation: exploring the potential role of allopurinol in TXNIP–NLRP3 signaling and pyroptosis in diabetes
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia and progressive multi-org...
An NLRP3 inflammasome inhibitor evoked dose-dependent anti-allodynia in the hindpaws of a rat model of chemotherapy-induced peripheral neuropathy
An NLRP3 inflammasome inhibitor evoked dose-dependent anti-allodynia in the hindpaws of a rat model of chemotherapy-induced peripheral neuropathy
Patients receiving chemotherapy for cancer treatment may develop chemotherapy-induced peripheral neuropathy (CIPN), a type...
Hormonal therapies for endometriosis-associated pain: inflammatory limitations and pharmacological challenges
Hormonal therapies for endometriosis-associated pain: inflammatory limitations and pharmacological challenges
Endometriosis is a chronic inflammatory and estrogen-dependent disease in which pain remains the leading cause of impaired...
Dimethyl itaconate attenuates dextran sulfate sodium-induced ulcerative colitis in BALB/c mice: investigations on the TXNIP/NLRP3 inflammasome signaling pathway
Dimethyl itaconate attenuates dextran sulfate sodium-induced ulcerative colitis in BALB/c mice: investigations on the TXNIP/NLRP3 inflammasome signaling pathway
Ulcerative colitis (UC) involves recurrent colonic mucosal inflammation and impaired epithelial repair. Current therapies ...
Evaluation of anti-arthritic activity of aripiprazole through multi models: new potential of an old drug
Evaluation of anti-arthritic activity of aripiprazole through multi models: new potential of an old drug
This study was conducted to investigate the anti-arthritic effect of three different doses of aripiprazole based on its pr...
and Alzheimer’s disease: mechanistic convergence, cognitive outcomes and translational perspectives
and Alzheimer’s disease: mechanistic convergence, cognitive outcomes and translational perspectives
Alzheimer’s disease (AD), the leading cause of age-related cognitive decline and dementia, represents a growing neur...
Neuroinflammatory and molecular pathways in Alzheimer’s disease: mechanistic crosstalk and emerging therapeutic opportunities
Neuroinflammatory and molecular pathways in Alzheimer’s disease: mechanistic crosstalk and emerging therapeutic opportunities
Alzheimer’s disease (AD) is a multifactorial and progressive neurodegenerative condition characterized by the intera...
Low-dose aspirin in pregnancy: indications, efficacy, safety, and remaining controversies
Low-dose aspirin in pregnancy: indications, efficacy, safety, and remaining controversies
Aspirin is widely used in obstetric practice, but its effects in pregnancy depend strongly on indication, dose, and timing...
Caspase-1 inhibition: mechanistic insights and comprehensive review of reported inhibitors to date
Caspase-1 inhibition: mechanistic insights and comprehensive review of reported inhibitors to date
Caspase-1 is a key protease that regulates inflammation by mediating the maturation of pro-inflammatory cytokines IL-1^...
The beneficial properties of CBDA in diet-induced neuroinflammation
The beneficial properties of CBDA in diet-induced neuroinflammation
Cannabidiolic acid (CBDA) is a phytocannabinoid found in the Cannabis plant. Understanding the effects of CBDA is essentia...
Emerging diagnostic biomarkers and therapeutic targets in Alzheimer's disease
Emerging diagnostic biomarkers and therapeutic targets in Alzheimer's disease
Alzheimer's disease (AD) is a progressive neurodegenerative disease and is the most common cause of dementia in the wo...
Role of mGluR7 in Alzheimer’s disease: pathophysiological insights and therapeutic approaches
Role of mGluR7 in Alzheimer’s disease: pathophysiological insights and therapeutic approaches
Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterised by oxidative stress, mitochondrial...
Targeting TREM-1 receptors with metformin and pravastatin modulate monosodium iodoacetate-induced osteoarthritis
Targeting TREM-1 receptors with metformin and pravastatin modulate monosodium iodoacetate-induced osteoarthritis
Osteoarthritis (OA), a degenerative joint condition, affects entire joints, including the tissues around it, causing pain,...
Chaperone-mediated autophagy, heat shock protein 70, and serotonin: novel targets of beta-hydroxybutyrate in HFFD/LPS-induced sporadic Alzheimer’s disease model
Chaperone-mediated autophagy, heat shock protein 70, and serotonin: novel targets of beta-hydroxybutyrate in HFFD/LPS-induced sporadic Alzheimer’s disease model
Sporadic Alzheimer’s disease (AD), which accounts for the majority of cases, is sturdily influenced by lifestyle fac...
Impact of NSAIDs corticosteroids DMARDs biologics and their comparisons with natural products in C-reactive proteins (CRP) linked cardiovascular disorders
Impact of NSAIDs corticosteroids DMARDs biologics and their comparisons with natural products in C-reactive proteins (CRP) linked cardiovascular disorders
An important part of the pathophysiology of atherosclerosis is the involvement of inflammatory processes, which mediate va...
Anti-arthritic potential and mechanistic insights of methanol extract of Engl. in complete Freund’s adjuvant-induced rats
Anti-arthritic potential and mechanistic insights of methanol extract of Engl. in complete Freund’s adjuvant-induced rats
This study determined the phytochemical profile and in vivo anti-arthritic potential and mechanistic effects of MeOH extra...
Empagliflozin and memantine combination ameliorates cognitive impairment in scopolamine + heavy metal mixture-induced Alzheimer’s disease in rats: role of AMPK/mTOR, BDNF, BACE-1, neuroinflammation, and oxidative stress
Empagliflozin and memantine combination ameliorates cognitive impairment in scopolamine + heavy metal mixture-induced Alzheimer’s disease in rats: role of AMPK/mTOR, BDNF, BACE-1, neuroinflammation, and oxidative stress
One of the major consequences of diabetes mellitus that has gained attention due to its rising incidence is cognitive impa...
Bioactive potential of with detailed insight into anti-inflammatory activity through in vitro, in vivo evaluations and network pharmacology
Bioactive potential of with detailed insight into anti-inflammatory activity through in vitro, in vivo evaluations and network pharmacology
This study evaluated Tripleurospermum inodorum extract for cytotoxic, anti-inflammatory, antioxidant, antimicrobial, and a...
Amelioration of pain and adjuvant-induced arthritis by syringic acid via modulation of behavioral parameters and inflammatory mediators i.e. TNF-α, Interleukins, MCP-1, NF-kB and COX-2
Amelioration of pain and adjuvant-induced arthritis by syringic acid via modulation of behavioral parameters and inflammatory mediators i.e. TNF-α, Interleukins, MCP-1, NF-kB and COX-2
Syringic acid with reported anti-inflammatory attribute was investigated in the present study to assess its anti-arthritic...
A comprehensive review of the impact of natural products in preventing drug-induced ototoxicity
A comprehensive review of the impact of natural products in preventing drug-induced ototoxicity
Ototoxicity, the property of certain drugs to cause hearing loss, is a significant concern in medical treatments, particul...
Exploring the potential of seed extract-loaded microemulsion hydrogel in the DNCB-induced atopic dermatitis model
Exploring the potential of seed extract-loaded microemulsion hydrogel in the DNCB-induced atopic dermatitis model
Moringa oleifera n-hexane (MO n-Hex) seed extract contains phytoconstituents such as behenic acid, quercetin, and kaempfer...
From receptor to response: dissecting the TLR4 pathway in diabetic neuropathy
From receptor to response: dissecting the TLR4 pathway in diabetic neuropathy
Diabetic neuropathy (DNP) is a common complication of diabetes that has a significant impact on the patient’s qualit...
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