Bahrami A, Barreto GE, Lombardi G, Pirro M, Sahebkar A (2019) Emerging roles for high-density lipoproteins in neurodegenerative disorders. BioFactors 45:725–739
Article CAS PubMed Google Scholar
Björkhem I, Meaney S, Fogelman AM (2004) Brain cholesterol: long secret life behind a barrier. Arterioscler Thromb Vasc Biol 24:806–815
Bowman GL, Dayon L, Kirkland R et al (2018) Blood-brain Barrer breakdown, neuroinflammation, and cognitive decline in older adults. Alzheimers Dement 14:1640–1650
Charisis S, Lu S, Melgarejo JD et al (2025) Association of blood lipoprotein levels with incident alzheimer disease in Community-Dwelling individuals: the Framingham heart study. Neurology 104:e213715
Article CAS PubMed PubMed Central Google Scholar
Che B, Zhong C, Zhang R et al (2023) Triglyceride-glucose index and triglyceride to high-density lipoprotein cholesterol ratio as potential cardiovascular disease risk factors: an analysis of UK biobank data. Cardiovasc Diabetol 22:34
Article CAS PubMed PubMed Central Google Scholar
Dou Y, Liu S, Li Y, Wu H, Chen H, Ji Y (2022) Plasma cholesterol levels as potential nutritional biomarkers for lewy body dementia. J Alzheimers Dis 86:779–786
Article CAS PubMed Google Scholar
Ferguson EL, Zimmerman SC, Jiang C et al (2025) Independent associations of high-density lipoprotein cholesterol and triglyceride levels with alzheimer’ disease and related dementias. Alzheimers Dement 21:e14575
Article CAS PubMed PubMed Central Google Scholar
Gang L, Yanyan Z (2016) Increased neutrophil to lymphocyte ratio in persons suffering from hypertension with hyperhomocysteinemia. Hypertens Res 39:606–611
Giannini C, Santoro N, Caprio S et al (2011) The triglyceride-to-HDL-C ratio: association with insulin resistance in obese youths of different ethnic backgrounds. Diabetes Care 34:1869–1874
Article PubMed PubMed Central Google Scholar
Hansen SB, Wang H (2023) The shared role of cholesterol in neuronal and peripheral inflammation. Pharmacol Ther 249:108486
Article CAS PubMed Google Scholar
Hashimoto Y, Fukazawa K, Fujii M et al (2004) Usefulness of the odor stick identification test for Japanese patients with olfactory dysfunction. Chem Senses 29:565–571
Hsiao JT, Halliday GM, Kim WS (2017) alpha-Synuclein regulates neuronal cholesterol efflux. Molecules 22:1769
Article PubMed PubMed Central Google Scholar
Hussain SM, Robb C, Tonkin AM et al (2023) Association of plasma high-density lipoprotein cholesterol level with risk of incident dementia: a cohort study of healthy older adults. Lancet Reg Health West Pac 43:100963
PubMed PubMed Central Google Scholar
Jellinger KA (2018) Dementia with lewy bodies and parkinson’s disease-dementia: current concepts and controversies. J Neural Transm 125:615–650
Article CAS PubMed Google Scholar
Jiang M, Sun J, Zou H, Li M, Su Z, Sun W, Kong X (2022) Prognostic role of neutrophil to High-Density lipoprotein cholesterol ratio for All-Cause and cardiovascular mortality in the general population. Front Cardiovasc Med 9:807339
Article CAS PubMed PubMed Central Google Scholar
Kagi G, Bhatia KP, Tolosa E (2010) The role of DAT-SPECT in movement disorders. J Neurol Neurosurg Psychiatry 81:5–12
Article CAS PubMed Google Scholar
Kakoty V, Kc S, Kumari S et al (2023) Brain insulin resistance linked alzheimer’s and parkinson’s disease pathology: an undying implication of epigenetic and autophagy modulation. Inflammopharmacology 31:699–716
Article CAS PubMed Google Scholar
King E, O’Brien JT, Donaghy P et al (2018) Peripheral inflammation in prodromal alzheimer’s and lewy body dementias. J Neurol Neurosurg Psychiatry 89:339–345
Kwak IH, Kim YE, Kim YJ et al (2024) Monocyte to high-density lipoprotein cholesterol ratio reflects the peripheral inflammatory state in parkinsonian disorders. Parkinsonism Relat Disord 129:107155
Article CAS PubMed Google Scholar
Li F, Weng G, Zhou H et al (2024) The neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio, and neutrophil-to-high-density-lipoprotein ratio are correlated with the severity of parkinson’s disease. Front Neurol 15:1322228
Article PubMed PubMed Central Google Scholar
McKeith IG, Dickson DW, Lowe J et al (2005) Diagnosis and management of dementia with lewy bodies: third report of the DLB consortium. Neurology 65:1863–1872
Article CAS PubMed Google Scholar
McKeith IG, Boeve BF, Dickson DW et al (2017) Diagnosis and management of dementia with lewy bodies: fourth consensus report of the DLB consortium. Neurology 89:88–100
Article PubMed PubMed Central Google Scholar
Mehta NH, Zhou L, Li Y et al (2023) Peripheral immune cell imbalance is associated with cortical beta-amyloid deposition and longitudinal cognitive decline. Sci Rep 13:8847
Article CAS PubMed PubMed Central Google Scholar
Murphy AJ, Woollard KJ, Suhartoyo A et al (2011) Neutrophil activation is attenuated by high-density lipoprotein and Apolipoprotein A-I in in in vitro and in vivo models of inflammation. Arterioscler Thromb Vasc Biol 31:1333–1341
Article CAS PubMed Google Scholar
Nazir S, Jankowski V, Bender G, Zewinger S, Rye KA, van der Vorst EPC (2020) Interaction between hih-density lipoproteins and inflammation: function matters more than concentration! Adv Drug Deliv Rev 159:94–119
Article CAS PubMed Google Scholar
Ogihara H, Kobayashi M, Nishida K, Kitano M, Takeuchi K (2011) Applicability of the cross-culturally modified university of Pennsylvania smell identification test in a Japanese population. Am J Rhinol Allergy 25:404–410
Park JH, Lee CW, Nam MJ et al (2021) Association of High-Density lipoprotein cholesterol variability and the risk of developing Parkinson disease. Neurology 96:e1391–e1401
Article CAS PubMed Google Scholar
Postuma RB, Lang AE (2004) Homocysteine and levodopa: should Parkinson disease patients receive preventative therapy? Neurology 63:886–891
Article CAS PubMed Google Scholar
Reitz C, Tang MX, Schupf N, Manly JJ, Mayeux R, Luchsinger JA (2010) Association of higher levels of high-density lipoprotein cholesterol in elderly individuals and lower risk of late-onset alzheimer disease. Arch Neurol 67:1491–1497
Article PubMed PubMed Central Google Scholar
Ren H, Zhu B, Zhao Z et al (2023) Neutrophil to high-density lipoprotein cholesterol ratio as the risk mark in patients with type 2 diabetes combined with acute coronary syndrome: a cross-sectional study. Sci Rep 13:7836
Article CAS PubMed PubMed Central Google Scholar
Robert J, Stukas S, Button E et al (2016) Reconstituted high-density lipoproteins acutely reduce soluble brain Abeta levels in symptomatic APP/PS1 mice. Biochim Biophys Acta 1862:1027–1036
Article CAS PubMed Google Scholar
Rosenson RS, Brewer HB Jr, Ansell BJ e
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