Abbas M, Rahman S (2016) Effects of alpha-7 nicotinic acetylcholine receptor positive allosteric modulator on lipopolysaccharide-induced neuroinflammatory pain in mice. Eur J Pharmacol 783:85–91
Article CAS PubMed Google Scholar
Abbas M, Alzarea S, Papke RL, Rahman S (2019) The α7 nicotinic acetylcholine receptor positive allosteric modulator prevents lipopolysaccharide-induced allodynia, hyperalgesia and TNF-α in the hippocampus in mice. Pharmacol Rep 71:1168–1176
Article CAS PubMed PubMed Central Google Scholar
AboulMagd AM, Abdelwahab NS, Abdelrahman MM, Abdel-Rahman HM, Farid NF (2021) Lipophilicity study of different cephalosporins: computational prediction of minimum inhibitory concentration using salting-out chromatography. J Pharm Biomed Anal 206:114358
Article CAS PubMed Google Scholar
Akina S, Thati M, Puchchakayala G (2013) Neuroprotective effect of ceftriaxone and selegiline on scopolamine induced cognitive impairment in mice. Adv Biol Res 7:266–275
Alotaibi G, Rahman S (2019) Effects of glial glutamate transporter activator in formalin-induced pain behaviour in mice. Eur J Pain 23:765–783
Article CAS PubMed Google Scholar
Alotaibi G, Khan A, Ronan PJ, Lutfy K, Rahman S (2023) Glial glutamate transporter modulation prevents development of complete Freund’s adjuvant-induced hyperalgesia and allodynia in mice. Brain Sci 13:807
Article CAS PubMed PubMed Central Google Scholar
Alotaibi G, Khan A, Rahman S (2025) Glutamate transporter activator LDN-212320 prevents chronic pain-induced cognitive impairment and anxiety-like behaviors in a mouse model. Behav Brain Res. https://doi.org/10.1016/j.bbr.2025.115440
Althubyani AA, Canto S, Pham H, Holger DJ, Rey J (2024) Antibiotic-induced neuropsychiatric toxicity: epidemiology, mechanisms and management strategies–a narrative literature review. Drugs Context. https://doi.org/10.7573/dic.2024-3-3
Article PubMed PubMed Central Google Scholar
Alzarea S, Rahman S (2018) Effects of alpha-7 nicotinic allosteric modulator PNU 120596 on depressive-like behavior after lipopolysaccharide administration in mice. Prog Neuropsychopharmacol Biol Psychiatry 86:218–228
Article CAS PubMed Google Scholar
Alzarea S, Rahman S (2019) Alpha-7 nicotinic receptor allosteric modulator PNU120596 prevents lipopolysaccharide-induced anxiety, cognitive deficit and depression-like behaviors in mice. Behav Brain Res 366:19–28
Article CAS PubMed Google Scholar
Alzarea S, Rahman S (2025) The alpha-7 nicotinic receptor positive allosteric modulator PNU120596 attenuates lipopolysaccharide-induced depressive-like behaviors and cognitive impairment by regulating the PPAR-α signaling pathway in mice. CNS & Neurological Disorders-Drug Targets 24:234–244
Alzarea S, Khan A, Ronan PJ, Lutfy K, Rahman S (2024) The α-7 nicotinic receptor positive allosteric modulator alleviates lipopolysaccharide induced depressive-like behavior by regulating microglial function, trophic factor, and chloride transporters in mice. Brain Sci 14:290
Article CAS PubMed PubMed Central Google Scholar
Amakhin DV, Soboleva EB, Zaitsev AV (2018) Cephalosporin antibiotics are weak blockers of GABAa receptor-mediated synaptic transmission in rat brain slices. Biochem Biophys Res Commun 499:868–874
Article CAS PubMed Google Scholar
Amakhin DV, Smolensky IV, Soboleva EB, Zaitsev AV (2020) Paradoxical anticonvulsant effect of cefepime in the pentylenetetrazole model of seizures in rats. Pharmaceuticals 13:80
Article CAS PubMed PubMed Central Google Scholar
Amawi H, Alsheyab S, Hammad AM, Alhazaimeh R, Maklouf T, Al-Trad B, Almarghalani DA, Alzahrani MS, Ashby JCR, Tiwari AK (2025) Dapagliflozin reverses LPS-induced depressive-like behavior in mice via modulation of glutamate and NF-κb. Genes Brain Behav 24:e70037
Article CAS PubMed PubMed Central Google Scholar
An D, Wei C, Wang J, Wu A (2021) Intranasal ketamine for depression in adults: a systematic review and meta-analysis of randomized, double-blind, placebo-controlled trials. Front Psychol 12:648691
Article PubMed PubMed Central Google Scholar
Baeza-Flores GdC, Rodríguez-Palma EJ, Reyes-Pérez V, Guzmán-Priego CG, Torres-López JE (2020) Antinociceptive effects of ceftriaxone in formalin-induced nociception. Drug Dev Res 81:728–735
Article CAS PubMed Google Scholar
Baganz N, Lindler K, Zhu C, Smith J, Robson M, Iwamoto H, Deneris E, Hewlett W, Blakely R (2015) A requirement of serotonergic p38α mitogen-activated protein kinase for peripheral immune system activation of CNS serotonin uptake and serotonin-linked behaviors. Transl Psychiatry 5:e671–e671
Barcelon EE, Cho W-H, Jun SB, Lee SJ (2019) Brain microglial activation in chronic pain-associated affective disorder. Front Neurosci 13:213
Article PubMed PubMed Central Google Scholar
Beach SR, Kostis WJ, Celano CM, Januzzi JL, Ruskin JN, Noseworthy PA, Huffman JC (2014) Meta-analysis of selective serotonin reuptake inhibitor-associated QTc prolongation. J Clin Psychiatry 75:e441-449
Bechtholt-Gompf AJ, Walther HV, Adams MA, Carlezon WA, Öngür D, Cohen BM (2010) Blockade of astrocytic glutamate uptake in rats induces signs of anhedonia and impaired spatial memory. Neuropsychopharmacology 35:2049–2059
Article CAS PubMed PubMed Central Google Scholar
Ben Menachem-Zidon O, Goshen I, Kreisel T, Ben Menahem Y, Reinhartz E, Ben Hur T, Yirmiya R (2008) Intrahippocampal transplantation of transgenic neural precursor cells overexpressing interleukin-1 receptor antagonist blocks chronic isolation-induced impairment in memory and neurogenesis. Neuropsychopharmacology 33:2251–2262
Article CAS PubMed Google Scholar
Biesmans S, Meert TF, Bouwknecht JA, Acton PD, Davoodi N, De Haes P, Kuijlaars J, Langlois X, Matthews LJ, VerDonck L (2013) Systemic immune activation leads to neuroinflammation and sickness behavior in mice. Mediators of inflammation. 2013:271359
Article PubMed PubMed Central Google Scholar
Bisht R, Kaur B, Gupta H, Prakash A (2014) Ceftriaxone mediated rescue of nigral oxidative damage and motor deficits in MPTP model of Parkinson’s disease in rats. Neurotoxicology 44:71–79
Article CAS PubMed Google Scholar
Bowyer JF, Sarkar S, Burks SM, Hess JN, Tolani S, O’Callaghan JP, Hanig JP (2020) Microglial activation and responses to vasculature that result from an acute LPS exposure. Neurotoxicology 77:181–192
Article CAS PubMed PubMed Central Google Scholar
Buntinx M, Moreels M, Vandenabeele F, Lambrichts I, Raus J, Steels P, Stinissen P, Ameloot M (2004) Cytokine-induced cell death in human oligodendroglial cell lines: I. synergistic effects of IFN-γ and TNF-α on apoptosis. J Neurosci Res 76:834–845
Article CAS PubMed Google Scholar
Capuron L, Miller AH (2011) Immune system to brain signaling: neuropsychopharmacological implications. Pharmacol Ther 130:226–238
Article CAS PubMed PubMed Central Google Scholar
Cazareth J, Guyon A, Heurteaux C, Chabry J, Petit-Paitel A (2014) Molecular and cellular neuroinflammatory status of mouse brain after systemic lipopolysaccharide challenge: importance of CCR2/CCL2 signaling. J Neuroinflammation 11:132
Article PubMed PubMed Central Google Scholar
Charan J, Biswas T (2013) How to calculate sample size for different study designs in medical research? Indian J Psychol Med 35:121–126
Article PubMed PubMed Central Google Scholar
Chaudhary M, Soni A, Dwivedi VK (2008) Fixed dose combination of cefepime plus amikacin prevent oxidative stress in liver of Mus musculus mice. Curr Clin Pharmacol 3:211–214
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