Multi-institutional study of multileaf collimator parameters and dose calculation accuracy using the enhanced leaf model

Hartgerink D, Swinnen A, Roberge D, Nichol A, Zygmanski P, Yin F-F, et al. LINAC based stereotactic radiosurgery for multiple brain metastases: guidance for clinical implementation. Acta Oncol (Madr) [Internet]. 2019;58:1275–82. https://doi.org/10.1080/0284186X.2019.1633016.

Article  Google Scholar 

Milano MT, Grimm J, Niemierko A, Soltys SG, Moiseenko V, Redmond KJ, et al. Single- and multifraction stereotactic radiosurgery dose/volume tolerances of the brain. Int J Radiation Oncol Biol Phys [Internet]. 2021;110:68–86. https://doi.org/10.1016/j.ijrobp.2020.08.013.

Article  Google Scholar 

Van Esch A, Kulmala A, Rochford R, Kauppinen J, Harju A. Testing of an enhanced leaf model for improved dose calculation in a commercial treatment planning system. Med Phys [Internet]. 2022;49:7754–65. https://doi.org/10.1002/mp.16019.

Article  PubMed  Google Scholar 

Lankinen L, Kulmala A, Lehtomäki J, Harju A. The delivery assessment for small targets on Halcyon radiotherapy system – measured and calculated dose comparison. J Appl Clin Med Phys [Internet]. 2024. https://doi.org/10.1002/acm2.14407.

Article  PubMed  PubMed Central  Google Scholar 

Miyasaka R, Shirai M, Igari M, Kojima Y, Kozawa Y, Kawachi T, et al. Commissioning of Halcyon enhanced leaf model in the Eclipse treatment planning system: Focus on simple slit fields and VMAT dose calculation. J Appl Clin Med Phys [Internet]. 2025. https://doi.org/10.1002/acm2.70044.

Article  PubMed  PubMed Central  Google Scholar 

Moktan H, Jiang H, Li HH, Guida K. Impact of enhanced leaf model on dose calculation accuracy in single-isocenter multitarget stereotactic radiosurgery treatments. J Appl Clin Med Phys. 2025. https://doi.org/10.1002/acm2.70039.

Article  PubMed  PubMed Central  Google Scholar 

Koger B, Price R, Wang D, Toomeh D, Geneser S, Ford E. Impact of the MLC leaf-tip model in a commercial TPS: dose calculation limitations and IROC-H phantom failures. J Appl Clin Med Phys [Internet]. 2020;21:82–8. https://doi.org/10.1002/acm2.12819.

Article  PubMed  PubMed Central  Google Scholar 

May L, Hardcastle N, Hernandez V, Saez J, Rosenfeld A, Poder J. Multi-institutional investigation into the robustness of intra-cranial multi-target stereotactic radiosurgery plans to delivery errors. Med Phys [Internet]. 2024;51:910–21. https://doi.org/10.1002/mp.16907.

Article  CAS  PubMed  Google Scholar 

Isono M, Akino Y, Mizuno H, Tanaka Y, Masai N, Yamamoto T. Inter-unit variability of multi-leaf collimator parameters for IMRT and VMAT treatment planning: a multi-institutional survey. J Radiat Res [Internet]. 2020;61:307–13. https://doi.org/10.1093/jrr/rrz082.

Article  PubMed  PubMed Central  Google Scholar 

James S, Al-Basheer A, Elder E, Huh C, Ackerman C, Barrett J, et al. Evaluation of commercial devices for patient specific QA of stereotactic radiotherapy plans. J Appl Clin Med Phys. 2023. https://doi.org/10.1002/acm2.14009.

Article  PubMed  PubMed Central  Google Scholar 

Mukwada G, Chamunyonga C, Rowshanfarzad P, Gill S, Ebert MA. Insights into the dosimetric and geometric characteristics of stereotactic radiosurgery for multiple brain metastases: a systematic review. PLoS ONE. 2024;19:e0307088. https://doi.org/10.1371/journal.pone.0307088.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Timakova E, Zavgorodni SF. Effect of modulation factor and low dose threshold level on gamma pass rates of single isocenter multi‐target SRT treatment plans. J Appl Clin Med Phys. 2024. https://doi.org/10.1002/acm2.14459.

Article  PubMed  PubMed Central  Google Scholar 

Cirino E, Benedict SH, Dupre PJ, Halvorsen PH, Kim GG, Reyhan ML, et al. AAPM‐RSS medical physics practice guideline 9.b: SRS‐SBRT. J Appl Clin Med Phys. 2025. https://doi.org/10.1002/acm2.14624.

Article  PubMed  PubMed Central  Google Scholar 

Infusino E, Ianiro A, Luppino S, Nocentini S, Pugliatti C, Soriani A. Evaluation of a planar diode matrix for SRS patient‐specific QA in comparison with GAFchromic films. J Appl Clin Med Phys. 2023. https://doi.org/10.1002/acm2.13947.

Article  PubMed  PubMed Central  Google Scholar 

Panagi R, Caines R, Rowbottom CG. Dosimetric sensitivity of an enhanced leaf model (ELM) for individual versus averaged machines. J Appl Clin Med Phys. 2025. https://doi.org/10.1002/acm2.14621.

Article  PubMed  PubMed Central  Google Scholar 

Jumonji K, Takatsu J, Hara N, Fan R, Shimomura R, Inoue T, et al. Patient‐specific quality assurance for extremely small field sizes using 3D in vivo dosimetry in fractionated stereotactic radiosurgery for brain metastases. J Appl Clin Med Phys. 2026. https://doi.org/10.1002/acm2.70417.

Article  PubMed  PubMed Central  Google Scholar 

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