Belboul A, Ashworth J, Fadel A, McLoughlin J, Mahmoud A, El Mohtadi M (2025) Estrogen induces the alternative activation of macrophages through binding to estrogen receptor-alpha. Exp Mol Pathol 143:104971. https://doi.org/10.1016/j.yexmp.2025.104971

Article  CAS  PubMed  Google Scholar 

Borgert CJ (2023) Issue analysis: key characteristics approach for identifying endocrine disruptors. Arch Toxicol 97(10):2819–2822. https://doi.org/10.1007/s00204-023-03568-3

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brough Z, Zhao Z, Duong van Hoa F (2024) From bottom-up to cell surface proteomics: detergents or no detergents, that is the question. Biochem Soc Trans 52(3):1253–1263. https://doi.org/10.1042/BST20231020

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bulbring E, Burn JH (1935) The estimation of oestrin and of male hormone in oily solution. J Physiol 85(3):320–333. https://doi.org/10.1113/jphysiol.1935.sp003321

Article  CAS  PubMed  PubMed Central  Google Scholar 

Campbell L, Emmerson E, Williams H et al (2014) Estrogen receptor-alpha promotes alternative macrophage activation during cutaneous repair. J Invest Dermatol 134(9):2447–2457. https://doi.org/10.1038/jid.2014.175

Article  CAS  PubMed  Google Scholar 

Coates HW, Nguyen TB, Du X et al (2024) The constitutively active form of a key cholesterol synthesis enzyme is lipid droplet-localized and upregulated in endometrial cancer tissues. J Biol Chem 300(5):107232. https://doi.org/10.1016/j.jbc.2024.107232

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dorfman RI, Dorfman AS (1954) Estrogen assays using the rat uterus. Endocrinology 55(1):65–69. https://doi.org/10.1210/endo-55-1-65

Article  CAS  PubMed  Google Scholar 

EPA (2025) U.S. Environmental Protection Agency Endocrine Disruptor Screening Program (EDSP). https://www.epa.gov/test-guidelines-pesticides-and-toxic-substances/edsp-test-guidelines-and-guidance-document

Fertuck KC, Eckel JE, Gennings C, Zacharewski TR (2003) Identification of temporal patterns of gene expression in the uteri of immature, ovariectomized mice following exposure to ethynylestradiol. Physiol Genomics 15(2):127–141. https://doi.org/10.1152/physiolgenomics.00058.2003

Article  CAS  PubMed  Google Scholar 

Finch-Edmondson M, Sudol M (2016) Framework to function: mechanosensitive regulators of gene transcription. Cell Mol Biol Lett 21:28. https://doi.org/10.1186/s11658-016-0028-7

Article  CAS  PubMed  PubMed Central  Google Scholar 

Garcia-Flores V, Romero R, Peyvandipour A et al (2023) A single-cell atlas of murine reproductive tissues during preterm labor. Cell Rep 42(1):111846. https://doi.org/10.1016/j.celrep.2022.111846

Article  CAS  PubMed  PubMed Central  Google Scholar 

Griffin NM, Schnitzer JE (2011) Overcoming key technological challenges in using mass spectrometry for mapping cell surfaces in tissues. Mol Cell Proteomics. https://doi.org/10.1074/mcp.R110.000935

Article  PubMed  Google Scholar 

Harding AT, Heaton NS (2022) The impact of estrogens and their receptors on immunity and inflammation during infection. Cancers (Basel). https://doi.org/10.3390/cancers14040909

Article  PubMed  PubMed Central  Google Scholar 

Hong K, Choi Y (2018) Role of estrogen and RAS signaling in repeated implantation failure. BMB Rep 51(5):225–229. https://doi.org/10.5483/bmbrep.2018.51.5.045

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hong EJ, Park SH, Choi KC, Leung PC, Jeung EB (2006) Identification of estrogen-regulated genes by microarray analysis of the uterus of immature rats exposed to endocrine disrupting chemicals. Reprod Biol Endocrinol 4:49. https://doi.org/10.1186/1477-7827-4-49

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hou X, Tan Y, Li M, Dey SK, Das SK (2004) Canonical Wnt signaling is critical to estrogen-mediated uterine growth. Mol Endocrinol 18(12):3035–3049. https://doi.org/10.1210/me.2004-0259

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang QH, Zhao GK, Wang HQ et al (2024) Single-cell transcriptional profile construction of rat pituitary glands before and after sexual maturation and identification of novel marker Spp1 in gonadotropes. Int J Mol Sci. https://doi.org/10.3390/ijms25094694

Article  PubMed  PubMed Central  Google Scholar 

Kanno J, Onyon L, Haseman J et al (2001) The OECD program to validate the rat uterotrophic bioassay to screen compounds for in vivo estrogenic responses: phase 1. Environ Health Perspect 109(8):785–794. https://doi.org/10.1289/ehp.01109785

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kelly MJ, Qiu J, Rønnekleiv OK (2005) Estrogen signaling in the hypothalamus vitamins & hormones, vol 71. Academic Press, pp 123–145

Google Scholar 

Kim HR, Cho KS, Kim E et al (2017) Rapid expression of RASD1 is regulated by estrogen receptor-dependent intracellular signaling pathway in the mouse uterus. Mol Cell Endocrinol 446:32–39. https://doi.org/10.1016/j.mce.2017.02.006

Article  CAS  PubMed  Google Scholar 

Kouzmenko AP, Takeyama K, Ito S et al (2004) Wnt/beta-catenin and estrogen signaling converge in vivo. J Biol Chem 279(39):40255–40258. https://doi.org/10.1074/jbc.C400331200

Article  CAS  PubMed  Google Scholar 

Kwekel JC, Burgoon LD, Burt JW, Harkema JR, Zacharewski TR (2005) A cross-species analysis of the rodent uterotrophic program: elucidation of conserved responses and targets of estrogen signaling. Physiol Genomics 23(3):327–342. https://doi.org/10.1152/physiolgenomics.00175.2005

Article  CAS  PubMed  Google Scholar 

La Merrill MA, Vandenberg LN, Smith MT et al (2020) Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification. Nat Rev Endocrinol 16(1):45–57. https://doi.org/10.1038/s41574-019-0273-8

Article  CAS  PubMed  Google Scholar 

Lee M, Marinoni I, Irmler M et al (2013) Transcriptome analysis of MENX-associated rat pituitary adenomas identifies novel molecular mechanisms involved in the pathogenesis of human pituitary gonadotroph adenomas. Acta Neuropathol 126(1):137–150. https://doi.org/10.1007/s00401-013-1132-7

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lee G, Suh Y, Kim B et al (2025) Estrogen upregulates nucleophosmin 1 expression in mouse uterus through MYC induction. Mol Cell Endocrinol 607:112612. https://doi.org/10.1016/j.mce.2025.112612

Article  CAS  PubMed  Google Scholar 

Lim LQJ, Adler L, Hajaj E et al (2024) ASS1 metabolically contributes to the nuclear and cytosolic p53-mediated DNA damage response. Nat Metab 6(7):1294–1309. https://doi.org/10.1038/s42255-024-01060-5

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lucia K, Monteserin-Garcia J, Buchfelder M, Renner U, Stalla G, Theodoropoulou M (2016) Hypoxia-inducible factor 1α triggers growth hormone synthesis in acromegalic tumors. In: Paper presented at the presented at 18th European congress of endocrinology, Munich, Germany

Matasconi M, Parini P, Angelin B, Rudling M (2005) Pituitary control of cholesterol metabolism in normal and LDL receptor knock-out mice: effects of hypophysectomy and growth hormone treatment. Biochim Biophys Acta 1736(3):221–227. https://doi.org/10.1016/j.bbalip.2005.08.012

Article  CAS  PubMed  Google Scholar 

Maurer RA (1979) Estrogen-induced prolactin and DNA synthesis in immature female rat pituitaries. Mol Cell Endocrinol 13(3):291–300. https://doi.org/10.1016/0303-7207(79)90088-1

Article