Kumar S, Itagi S. Opioid agonists and antagonists. In: Paul A, Anandabaskar N, Mathaiyan J, Raj GM, editors. Introduction to basics of pharmacology and toxicology. Essentials of systemic pharmacology: from principles to practice, vol. 2. Singapore: Springer Nature Singapore; 2021. p. 213–35.
Jayawardana S, Forman R, Johnston-Webber C, Campbell A, Berterame S, de Joncheere C, et al. Global consumption of prescription opioid analgesics between 2009–2019: a country-level observational study. EClinicalMedicine. 2021;42: 101198.
Article PubMed PubMed Central Google Scholar
Longo CJ, Heyland DK, Fisher HN, Fowler RA, Martin CM, Day AG. A long-term follow-up study investigating health-related quality of life and resource use in survivors of severe sepsis: comparison of recombinant human activated protein C with standard care. Crit Care. 2007;11(6):R128.
Article PubMed PubMed Central Google Scholar
Di Palo KE, Feder S, Baggenstos YT, Cornelio CK, Forman DE, Goyal P, et al. Palliative pharmacotherapy for cardiovascular disease: a scientific statement from the American Heart Association. Circ Cardiovasc Qual Outcomes. 2024;17(8): e000131.
Chow SL, Sasson C, Benjamin IJ, Califf RM, Compton WM, Oliva EM, et al. Opioid use and its relationship to cardiovascular disease and brain health: a presidential advisory from the American Heart Association. Circulation. 2021;144(13):e218–32.
Hagemeier NE. Introduction to the opioid epidemic: the economic burden on the healthcare system and impact on quality of life. Am J Manag Care. 2018;24(10 Suppl.):S200–6.
Peacock WF, Hollander JE, Diercks DB, Lopatin M, Fonarow G, Emerman CL. Morphine and outcomes in acute decompensated heart failure: an ADHERE analysis. Emerg Med J. 2008;25(4):205–9.
Article CAS PubMed Google Scholar
Behzadi M, Joukar S, Beik A. Opioids and cardiac arrhythmia: a literature review. Med Princ Pract. 2018;27(5):401–14.
Article PubMed PubMed Central Google Scholar
Golibkhon A, Akbar Gafur Ugli B, Makhamadjonov Farkhod Ugli M. Opioid agents and cardiac arrhythmia: a literature review. Cureus. 2023;15(4):e38007.
Toska E, Mayrovitz HN. Opioid impacts on cardiovascular health. Cureus. 2023;15(9): e46224.
PubMed PubMed Central Google Scholar
Qureshi WT, O’Neal WT, Khodneva Y, Judd S, Safford MM, Muntner P, et al. Association between opioid use and atrial fibrillation: the reasons for geographic and racial differences in stroke (REGARDS) study. JAMA Intern Med. 2015;175(6):1058–60.
Article PubMed PubMed Central Google Scholar
Chui PW, Khokhar A, Gordon KS, Dziura J, Burg MM, Brandt C, et al. Opioid prescription and risk of atrial fibrillation in younger veterans. Am Heart J. 2024;268:61–7.
Steffel J, Collins R, Antz M, Cornu P, Desteghe L, Haeusler KG, et al. 2021 European Heart Rhythm Association practical guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation. Europace. 2021;23(10):1612–76.
Article PubMed PubMed Central Google Scholar
Menichelli D, Pignatelli P, Brogi T, Pannunzio A, Violi F, Lip GYH, et al. Incidence of all-cause, cardiovascular, and atrial fibrillation-related hospitalizations: focus on antiarrhythmic drugs. JACC Adv. 2024;3(8): 101117.
Article PubMed PubMed Central Google Scholar
Hindricks G, Potpara T, Dagres N, Arbelo E, Bax JJ, Blomstrom-Lundqvist C, et al. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): The Task Force for the Diagnosis and Management of Atrial Fibrillation of the European Society of Cardiology (ESC) Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC. Eur Heart J. 2021;42(5):373–498.
Pastori DGG, Farcomeni A, Bucci T, Menichelli D, Franchino G, Pani A, et al. Venous thromboembolism in patients with atrial fibrillation: a systematic review and meta-analysis of 4,170,027 patients. JACC Adv. 2023;2(7): 100555.
Article PubMed PubMed Central Google Scholar
Khorana AA, Mackman N, Falanga A, Pabinger I, Noble S, Ageno W, et al. Cancer-associated venous thromboembolism. Nat Rev Dis Primers. 2022;8(1):11.
Pastori D, Marang A, Bisson A, Menichelli D, Herbert J, Lip GYH, et al. Thromboembolism, mortality, and bleeding in 2,435,541 atrial fibrillation patients with and without cancer: a nationwide cohort study. Cancer. 2021;127(12):2122–9.
Moher D, Shamseer L, Clarke M, Ghersi D, Liberati A, Petticrew M, et al. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev. 2015;4(1):1.
Article PubMed PubMed Central Google Scholar
Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;29(372): n71.
Sterne JA, Hernan MA, Reeves BC, Savovic J, Berkman ND, Viswanathan M, et al. ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ (Clin Res Ed). 2016;12(355): i4919.
McGuinness LA, Higgins JPT. Risk-of-bias VISualization (robvis): an R package and Shiny web app for visualizing risk-of-bias assessments. Res Synth Methods. 2021;12(1):55–61.
Lin AL, Nah G, Tang JJ, Vittinghoff E, Dewland TA, Marcus GM. Cannabis, cocaine, methamphetamine, and opiates increase the risk of incident atrial fibrillation. Eur Heart J. 2022;43(47):4933–42.
Article CAS PubMed Google Scholar
Harding BN, Wiggins KL, Jensen PN, McKnight B, Psaty BM, Heckbert SR, et al. Opioid, gabapentinoid, and nonsteroidal anti-inflammatory medication use and the risks of atrial fibrillation and supraventricular ectopy in the multi-ethnic study of atherosclerosis. Pharmacoepidemiol Drug Saf. 2020;29(9):1175–82.
Article CAS PubMed PubMed Central Google Scholar
Lee CW, Muo CH, Liang JA, Lin MC, Kao CH. Atrial fibrillation is associated with morphine treatment in female breast cancer patients: a retrospective population-based time-dependent cohort study. Medicine (Baltimore). 2016;95(11): e3102.
Article CAS PubMed Google Scholar
Chenaf C, Kabore JL, Delorme J, Pereira B, Mulliez A, Zenut M, et al. Prescription opioid analgesic use in France: trends and impact on morbidity-mortality. Eur J Pain. 2019;23(1):124–34.
Article CAS PubMed Google Scholar
Menichelli D, Vicario T, Ameri P, Toma M, Violi F, Pignatelli P, et al. Cancer and atrial fibrillation: epidemiology, mechanisms, and anticoagulation treatment. Progr Cardiovasc Dis. 2021;66:28–36.
Qin P, Nicholl BI, Ho FK, Hanlon P, Celis-Morales CA, Pell JP. Association between pain and incident arrhythmias in 422,654 individuals: evidence from the UK Biobank cohort. Eur J Prev Cardiol. 2025:zwaf153.
Chen Q, van Rein N, van der Hulle T, Heemelaar JC, Trines SA, Versteeg HH, et al. Coexisting atrial fibrillation and cancer: time trends and associations with mortality in a nationwide Dutch study. Eur Heart J. 2024;45(25):2201–13.
Article PubMed PubMed Central Google Scholar
Inoue K, Tajiri K, Xu D, Murakoshi N, Ieda M. Risk factors and in-hospital outcomes of perioperative atrial fibrillation for patients with cancer: a meta-analysis. Ann Surg Oncol. 2023;30(2):711–21.
Feng Y, He X, Yang Y, Chao D, Lazarus LH, Xia Y. Current research on opioid receptor function. Curr Drug Targets. 2012;13(2):230–46.
Article CAS PubMed PubMed Central Google Scholar
Bell SP, Sack MN, Patel A, Opie LH, Yellon DM. Delta opioid receptor stimulation mimics ischemic preconditioning in human heart muscle. J Am Coll Cardiol. 2000;36(7):2296–302.
Article CAS PubMed Google Scholar
Krantz MJ, Palmer RB, Haigney MCP. Cardiovascular complications of opioid use: JACC state-of-the-art review. J Am Coll Cardiol. 2021;77(2):205–23.
Article CAS PubMed Google Scholar
Lendeckel U, Muller C, Rocken C, Laube B, Tager M, Huth C, et al. Expression of opioid receptor subtypes and their ligands in fibrillating human atria. Pacing Clin Electrophysiol. 2005;28(Suppl. 1):S275–9.
Wong TM, Lee AY, Tai KK. Effects of drugs interacting with opioid receptors during normal perfusion or ischemia and reperfusion in the isolated rat heart: an attempt to identify cardiac opioid receptor subtype(s) involved in arrhythmogenesis. J Mol Cell Cardiol. 1990
Comments (0)