Paunovska, K. et al. A direct comparison of in vitro and in vivo nucleic acid delivery mediated by hundreds of nanoparticles reveals a weak correlation. Nano Lett. 18, 2148–2157 (2018).
Article CAS PubMed PubMed Central Google Scholar
Ngo, W. et al. Identifying cell receptors for the nanoparticle protein corona using genome screens. Nat. Chem. Biol. 18, 1023–1031 (2022).
Article CAS PubMed Google Scholar
Bussin, B. et al. Discovering nanoparticle corona ligands for liver macrophage capture. Nat. Nanotechnol. 20, 914–925 (2025).
Article CAS PubMed Google Scholar
Kim, M. et al. Exogenous RNA surveillance by proton-sensing TRIM25. Science 388, eads4539 (2025).
Article CAS PubMed Google Scholar
Chen, K. et al. Metabolic programming promotes cellular uptake of extracellular vesicles and boosts in vivo therapeutic efficacy. Cell Biomater. 2, 100409 (2026).
Chen, K. et al. Amino acid supplementation enhances in vivo efficacy of lipid nanoparticle–mediated mRNA delivery in preclinical models. Sci. Transl Med. 18, eadx4097 (2026).
Yu, X. et al. Metabolism-programming mRNA-lipid nanoparticles remodel the immune microenvironment to improve immunotherapy against MAFLD. Sci. Transl Med. 17, eadv2293 (2025).
Article CAS PubMed Google Scholar
Dobrowolski, C. et al. Nanoparticle single-cell multiomic readouts reveal that cell heterogeneity influences lipid nanoparticle-mediated messenger RNA delivery. Nat. Nanotechnol. 17, 871–879 (2022).
Article CAS PubMed PubMed Central Google Scholar
Levy, D. et al. Hijacking exosome biogenesis: viral glycoproteins as modular scaffolds for engineering functionalized extracellular vesicles. Nanoscale 18, 2252–2263 (2026).
Article CAS PubMed PubMed Central Google Scholar
Wang, W., Chen, K. & Wang, Z. Genome‐wide CRISPR screen reveals PIK3CA inhibition enhances lipid nanoparticle-mediated siRNA delivery. Adv. Sci. 13, e17617 (2026).
Comments (0)