Tsimberidou A-M. Targeted therapy in cancer. Cancer Chemother Pharmacol. 2015;76:1113–32. https://doi.org/10.1007/s00280-015-2861-1.
Article CAS PubMed PubMed Central Google Scholar
Halliday PR, Blakely CM, Bivona TG. Emerging Targeted Therapies for the Treatment of Non-small Cell Lung Cancer. Curr Oncol Rep. 2019;21:21. https://doi.org/10.1007/s11912-019-0770-x.
Roskoski R Jr. Properties of FDA-approved small molecule protein kinase inhibitors: A 2020 update. Pharmacol Res. 2020;152:104609. https://doi.org/10.1016/j.phrs.2019.104609.
Article CAS PubMed Google Scholar
Panda D, Saha P, Chaudhuri R, Prasanth T, Ravichandiran V, Dash J. A Competitive Pull-Down Assay Using G-quadruplex DNA Linked Magnetic Nanoparticles To Determine Specificity of G-quadruplex Ligands. Anal Chem. 2019;91:7705–11. https://doi.org/10.1021/acs.analchem.9b00889.
Article CAS PubMed Google Scholar
Prasanth T, Chakraborti G, Mandal T, Ravichandiran V, Dash J. Cycloaddition of N-sulfonyl and N-sulfamoyl azides with alkynes in aqueous media for the selective synthesis of 1,2,3-triazoles. Green Chem. 2022;24:911–5. https://doi.org/10.1039/D1GC03340A.
Saber SW, Al-Qawasmeh RA, Abu-Qatouseh L, Shtaiwi A, Khanfar MA, Al-Soud YA. Novel hybrid motifs of 4-nitroimidazole-piperazinyl tagged 1,2,3-triazoles: Synthesis, crystal structure, anticancer evaluations, and molecular docking study. Heliyon. 2023;9:e19327. https://doi.org/10.1016/j.heliyon.2023.e19327.
Article CAS PubMed PubMed Central Google Scholar
Maemondo M, et al. Gefitinib or Chemotherapy for Non–Small-Cell Lung Cancer with Mutated EGFR N. Engl J Med. 2010;362:2380–8 (https://www.nejm.org/doi/full/10.1056/NEJMoa0909530).
Sullivan I, Planchard D. Next-Generation EGFR Tyrosine Kinase Inhibitors for Treating EGFR-Mutant Lung Cancer beyond First Line. Front Med. 2017;3:76. https://doi.org/10.3389/fmed.2016.00076.
Sabbah DA, Hajjo R, Sweidan K. Review on epidermal growth factor receptor (EGFR) structure, signaling pathways, interactions, and recent updates of EGFR inhibitors. Curr Top Med Chem. 2020.
Huang L, Jiang S, Shi Y. Tyrosine kinase inhibitors for solid tumors in the past 20 years (2001–2020). J Hematol Oncol. 2020;13:143. https://doi.org/10.1186/s13045-020-00977-0.
Article CAS PubMed PubMed Central Google Scholar
Fatma K, Thumpati P, Panda D, Velayutham R, Dash J. Selective Recognition of c-KIT 1 G-Quadruplex by Structural Tuning of Heteroaromatic Scaffolds and Side Chains. ACS Med Chem Lett. 2024;15:388–95. https://doi.org/10.1021/acsmedchemlett.3c00537.
Article CAS PubMed Google Scholar
Hosomi Y, et al. Gefitinib Alone Versus Gefitinib Plus Chemotherapy for Non–Small-Cell Lung Cancer With Mutated Epidermal Growth Factor Receptor: NEJ009 Study. J Clin Oncol. 2020;38:115–23. https://doi.org/10.1200/jco.19.01488.
Article CAS PubMed Google Scholar
Zhao C, Han S-Y, Li P-P. Pharmacokinetics of Gefitinib: Roles of Drug Metabolizing Enzymes and Transporters. Curr Drug Deliv. 2017;14:282–8. https://doi.org/10.2174/1567201813666160709021605.
Article CAS PubMed Google Scholar
Godugu C, Doddapaneni R, Patel AR, Singh R, Mercer R, Singh M. Novel Gefitinib Formulation with Improved Oral Bioavailability in Treatment of A431 Skin Carcinoma. Pharm Res. 2016;33:137–54.
Article CAS PubMed Google Scholar
Patel AR, Chougule MB, Lim E, Francis KP, Safe S, Singh M. Theranostic tumor homing nanocarriers for the treatment of lung cancer. NBM. 2014;10:e1053–63. https://doi.org/10.1016/j.nano.2013.12.002.
Andey T, Sudhakar G, Marepally S, Patel A, Banerjee R, Singh M. Lipid nanocarriers of a lipid-conjugated estrogenic derivative inhibit tumor growth and enhance cisplatin activity against triple-negative breast cancer: pharmacokinetic and efficacy evaluation. Mol Pharm. 2015;12:1105–20. https://doi.org/10.1021/mp5008629.
Article CAS PubMed Google Scholar
Alshehri S, Alanazi A, Elzayat EM, Altamimi MA, Imam SS, Hussain A, Alqahtani F, Shakeel F. Formulation In Vitro and In Vivo Evaluation of Gefitinib Solid Dispersions Prepared Using Different Techniques. Processes. 2021;9:1210. https://doi.org/10.3390/pr9071210.
Shah PP, Desai PR, Channer D, Singh M. Enhanced skin permeation using polyarginine modified nanostructured lipid carriers. J Control Release. 2012;161:735–45. https://doi.org/10.1016/j.jconrel.2012.05.011.
Article CAS PubMed PubMed Central Google Scholar
Alshetaili AS. Gefitinib loaded PLGA and chitosan coated PLGA nanoparticles with magnified cytotoxicity against A549 lung cancer cell lines. Saudi J Biol Sci. 2021;28:5065–73. https://doi.org/10.1016/j.sjbs.2021.05.025.
Article CAS PubMed PubMed Central Google Scholar
Emami S, Shayanfar A. Deep eutectic solvents for pharmaceutical formulation and drug delivery applications. Pharm Dev Technol. 2020;25:779–96. https://doi.org/10.1080/10837450.2020.1735414.
Article CAS PubMed Google Scholar
Pedro SN, Freire MG, Freire CS, Silvestre AJ. Deep eutectic solvents comprising active pharmaceutical ingredients in the development of drug delivery systems. Expert Opin Drug Deliv. 2019;16:497–506. https://doi.org/10.1080/17425247.2019.1604680.
Silva JM, et al. Therapeutic role of deep eutectic solvents based on menthol and saturated fatty acids on wound healing ACS Appl. Bio Mater. 2019;2:4346–55. https://doi.org/10.1021/acsabm.9b00598.
El Achkar T, Greige-Gerges H, Fourmentin S. Basics and properties of deep eutectic solvents: a review. Environ Chem Lett. 2021;19:3397–408. https://doi.org/10.1007/s10311-021-01225-8.
Al-Mawla L, Al-Akayleh F, Daadoue S, Mahyoob W, Al-Tameemi B, Al-Remawi M, Adwan S, Agha ASA. Development, characterization, and ex vivo permeation assessment of diclofenac diethylamine deep eutectic systems across human skin. J Pharm Innov. 2023;18:2196–209. https://doi.org/10.1007/s12247-023-09784-9.
Adwan S, Qasmieh M, Al-Akayleh F, Ali Agha ASA. Recent Advances in Ocular Drug Delivery: Insights into Lyotropic Liquid Crystals. Pharmaceuticals. 2024;17:1315.
Article CAS PubMed PubMed Central Google Scholar
Alkhawaja B, Al-Akayleh F, Al-Khateeb A, Nasereddin J, Ghanim BY, Bolhuis A, Jaber N, Al-Remawi M, Qinna NA. Deep Eutectic Liquids as a Topical Vehicle for Tadalafil: Characterisation and Potential Wound Healing and Antimicrobial Activity. Molecules. 2023;28:2402. https://doi.org/10.3390/molecules28052402.
Article CAS PubMed PubMed Central Google Scholar
Al-Akayleh F, Khalid R, Hawash D, Al-Kaissi E, Al-Adham I, Al-Muhtaseb N, Jaber N, Al-Remawi M, Collier P. Antimicrobial potential of natural deep eutectic solvents. Lett Appl Microbiol. 2022;75:607–15. https://doi.org/10.1111/lam.13699.
Article CAS PubMed Google Scholar
McGaw L, Jäger A, Van Staden J. Antibacterial effects of fatty acids and related compounds from plants. S Afr J Bot. 2002;68:417–23. https://doi.org/10.1016/S0254-6299(15)30367-7.
Al-Akayleh F, Al-Remawi M, Agha A, Abu-Nameh E. Applications and Risk Assessments of Ionic Liquids in Chemical and Pharmaceutical Domains: An Updated Overview. Jordan J Chem. 2023;18:53–76. https://doi.org/10.47014/18.2.1.
Nakaweh A, Al-Akayleh F, Al-Remawi M, Abdallah Q, Agha AS. Deep Eutectic System-Based Liquisolid Nanoparticles as Drug Delivery System of Curcumin for In-Vitro Colon Cancer Cells. J Pharm Innov. 2024;19:1–11. https://doi.org/10.1007/s12247-024-09826-w.
Comments (0)