Stolom S, Oyemitan IA, Matewu R, Oyedeji OO, Oluwafemi SO, Nkeh-Chungag BN, et al. Chemical and biological studies of lobelia flaccida (C. Presl) A. DC leaf: a medicinal plant used by traditional healers in Eastern Cape, South Africa. Trop J Pharm Res. 2016;15(8):1715–21.

Article  CAS  Google Scholar 

Vishwakarma PK, Panigrahi TK, Sahoo J, Gaur N, Mishra P, Verma P, Tripathi SM. Therapeutic potential of lobelia inflata in promoting wound healing in male Wistar rat. Micro and Nanosystems; 2025.

ZIMARE SB, KAKADE PS. Comprehensive overview of the phytochemistry and Pharmacological studies of the genus Lobelia. Phytochemical composition and pharmacy of medicinal plants: 2-volume set. Oct. 2023;27:385–99.

Google Scholar 

Joshi S, Mishra D, Bisht G, Khetwal KS. Essential oil composition and antimicrobial activity of lobelia pyramidalis Wall. EXCLI J. 2011;10:274–9.

PubMed  PubMed Central  Google Scholar 

Waks AG, Winer EP. Breast cancer treatment: a review. JAMA. 2019;321(3):288–300.

Article  CAS  PubMed  Google Scholar 

Sun YS, Zhao Z, Yang ZN, Xu F, Lu HJ, Zhu ZY, Shi W, Jiang J, Yao PP, Zhu HP. Risk factors and preventions of breast cancer. Int J Biol Sci. 2017;13(11):1387.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Trayes KP, Cokenakes SE. Breast cancer treatment. Am Fam Physician. 2021;104(2):171–8.

PubMed  Google Scholar 

Watkins EJ. Overview of breast cancer. JAAPA. 2019;32(10):13–7.

Article  PubMed  Google Scholar 

Katsura C, Ogunmwonyi I, Kankam HK, Saha S. Breast cancer: presentation, investigation and management. Br J Hosp Med. 2022;83(2):1–7.

Article  Google Scholar 

Akram M, Iqbal M, Daniyal M, Khan AU. Awareness and current knowledge of breast cancer. Biol Res. 2017;50(1):33.

Article  PubMed  PubMed Central  Google Scholar 

Syu JP, Chi JT, Kung HN. Nrf2 is the key to chemotherapy resistance in MCF7 breast cancer cells under hypoxia. Oncotarget. 2016;7(12):14659.

Article  PubMed  PubMed Central  Google Scholar 

Nolan E, Lindeman GJ, Visvader JE. Deciphering breast cancer: from biology to the clinic. Cell. 2023;186(8):1708–28.

Article  CAS  PubMed  Google Scholar 

Hong R, Xu B. Breast cancer: an up-to‐date review and future perspectives. Cancer Commun. 2022;42(10):913–36.

Article  Google Scholar 

Moo TA, Sanford R, Dang C, Morrow M. Overview of breast cancer therapy. PET Clin. 2018;13(3):339.

Article  PubMed  PubMed Central  Google Scholar 

Bhat SA, Kumar V, Dhanjal DS, Gandhi Y, Mishra SK, Singh S, Webster TJ, Ramamurthy PC. Biogenic nanoparticles: pioneering a new era in breast cancer therapeutics-a comprehensive review. Discov Nano. 2024;19(1):121.

Article  PubMed  PubMed Central  Google Scholar 

Bharadwaj KK, Rabha B, Pati S, Sarkar T, Choudhury BK, Barman A, Bhattacharjya D, Srivastava A, Baishya D, Edinur HA. Abdul Kari Z, Mohd Noor NH. Green synthesis of gold nanoparticles using plant extracts as beneficial prospect for cancer theranostics. Molecules. 2021;26(21):6389.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nakamura Y, Mochida A, Choyke PL, Kobayashi H. Nanodrug delivery: is the enhanced permeability and retention effect sufficient for curing cancer? Bioconjug Chem. 2016;27(10):2225–38.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nisha, Sachan RS, Singh A, Karnwal A, Shidiki A, Kumar G. Plant-mediated gold nanoparticles in cancer therapy: exploring anti-cancer mechanisms, drug delivery applications, and future prospects. Front Nanatechnol. 2024;6:1490980.

Article  Google Scholar 

Tadele KT, Abire TO, Feyisa TY. Green synthesized silver nanoparticles using plant extracts as promising prospect for cancer therapy: a review of recent findings. J Nanomed. 2021;4:1040.

Google Scholar 

Nunez C, Estévez SV, del Pilar Chantada M. Inorganic nanoparticles in diagnosis and treatment of breast cancer. JBIC J Biol Inorg Chem. 2018;23(3):331–45.

Article  CAS  PubMed  Google Scholar 

Oehler JB, Rajapaksha W, Albrecht H. Emerging applications of nanoparticles in the diagnosis and treatment of breast cancer. J Personalized Med. 2024;14(7):723.

Article  Google Scholar 

Kumari M, Sharma N, Manchanda R, Gupta N, Syed A, Bahkali AH, Nimesh S. PGMD/curcumin nanoparticles for the treatment of breast cancer. Sci Rep. 2021;11(1):3824.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Patel P, Vedarethinam V, Korsah MA, Danquah MK, Jeevanandam J. Exploring the potential of nanoparticles in the treatment of breast cancer: current applications and future directions. Appl Sci. 2024;14(5):1809.

Article  CAS  Google Scholar 

Liu J, Liu G, Li J, Li X, Zhou H, Qiu C, Liu Y, Tan S, Almasi M. Green formulation of iron nanoparticles by plant extract induces apoptosis via P53 and STAT3 signaling pathways in prostate cancer cells. Inorg Chem Commun. 2024;162:112164.

Article  CAS  Google Scholar 

Xing T, Wang Z, Hao X, Mu J, Wang B. Copper nanoparticles green-formulated by curcuma longa extract induce apoptosis via P53 and STAT3 signaling pathways in bladder carcinoma cell. Biol Trace Elem Res. 2025;203(5):2606–18.

Article  CAS  PubMed  Google Scholar 

Mao M, Cui Z, Wei X, Liu T, Han M. Preparation, chemical characterization, and determination of the cytotoxicity and anti-thyroid cancer properties of pomegranate aqueous extract green‐synthesized silver nanoparticles following the STAT3 and p53 signaling pathways. Appl Organomet Chem. 2025;39(4):e70112.

Article  CAS  Google Scholar 

Xiao M, Li D, Li Y, Liang Y, Zhang J, Song Z. Green formulation and chemical characterization of iron nanoparticles containing Trifolium repens leaves extract for the treatment of atherosclerosis and gestational diabetes. Appl Organomet Chem. 2025;39(4):e70048.

Article  CAS  Google Scholar 

Ma H, Wang C, Li X, Sui D, Xu S. Efficiency of the green formulated iron nanoparticles as a new tool in lung cancer therapy. Arab J Chem. 2023;16(8):104928.

Article  CAS  Google Scholar 

Üstün E, Önbaş S, Çelik S, Ayvaz M, Şahin N. Green synthesis of iron oxide nanoparticles by using ficus carica leaf extract and its antioxidant activity. Biointerface Res. Appl. Chem. 2022, 2021, 2108–2116.

Yassin M, Mostafa A, Al-Askar A, Al-Otibi F. Facile green synthesis of zinc oxide nanoparticles with potential synergistic activity with common antifungal agents against multidrug-resistant candidal strains. Cryst (Basel. 2022;12:774.

CAS  Google Scholar 

Mandloi R, Jain A, Sharma B. Green synthesis of iron oxide (Fe2O3) nanoparticles using Neolamarckia cadamba leaves extract and photocatalytic degradation of malachite green. IJISRT. 2021;6:583–6.

Google Scholar 

Corrêa C, Siqueira A, Lopes P, Ambrosio J, Simionid A, Vasconcelos L, de Morais E. Green synthesis of iron nanoparticles from the Baru (Dipteryx Alata) endocarp extract for the efficient removal of Rhodamine B and caffeine from water through the heterogeneous Fenton process. AQUA — Water Infrastruct Ecosyst Soc. 2024;73:1358–71.

Article  Google Scholar 

Qasim S, Zafar A, Saif M, Ali Z, Nazar M, Waqas M, et al. Green synthesis of iron oxide nanorods using Withania coagulans extract improved photocatalytic degradation and antimicrobial activity. J Photochem Photobiol B. 2020;204:111784.

Article  CAS  PubMed  Google Scholar 

Mohamed A, Atta R, Kotp A, Abo El-Ela F, Abd El-Raheem H, Farghali A, Alkhalifah D, Hozzein W, Mahmoud R. Green synthesis and characterization of iron oxide nanoparticles for the removal of heavy metals (Cd2 + and Ni2+) from aqueous solutions with antimicrobial investigation. Sci Rep. 2023;13:1–30.

Google Scholar 

Yew Y, Shameli K, Mohamad S, Lee K, Teow S. Green synthesized Montmorillonite/Carrageenan/Fe3O4 nanocomposites for Ph-Responsive release of Protocatechuic acid and its anticancer activity. Int J Mol Sci. 2020;21(14):1–17.

Article  Google Scholar 

Yusefi M, Shameli K, Yee O, Teow S, Hedayatnasab Z, Jahangirian H, et al. Green synthesis of Fe3O4 nanoparticles stabilized by a garcinia Mangostana fruit peel extract for hyperthermia and anticancer activities. Int J Nanomed. 2021;16:2515–32.

Article  Google Scholar 

Shakil MS, Hasan MA, Sarker SR. Iron oxide nanoparticles for breast cancer theranostics. Curr Drug Metab. 2019;20(6):446–56.

Article  CAS  PubMed  Google Scholar 

Mu QG, Lin G, Jeon M, Wang H, Chang FC, Revia RA, Yu J, Zhang M. Iron oxide nanoparticle targeted chemo-immunotherapy for triple negative breast cancer. Mater Today (Kidlington). 2021;50:149–69.