Hunt DL, Castillo PE. Synaptic plasticity of NMDA receptors: mechanisms and functional implications. Curr Opin Neurobiol. 2012;22:496–508.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Bashir ZI, Alford S, Davies SN, Randall AD, Collingridge GL. Long-term potentiation of NMDA receptor-mediated synaptic transmission in the hippocampus. Nature. 1991;349:156–8.

Article  PubMed  CAS  Google Scholar 

Hansen KB, Wollmuth LP, Bowie D, Furukawa H, Menniti FS, Sobolevsky AI, et al. Structure, function, and pharmacology of glutamate receptor ion channels. Pharmacol Rev. 2021;73:1469–658.

Article  Google Scholar 

Kleckner NW, Dingledine R. Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes. Science. 1988;241:835–7.

Article  PubMed  CAS  Google Scholar 

Mayer ML, Westbrook GL, Guthrie PB. Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones. Nature. 1984;309:261–3.

Article  PubMed  CAS  Google Scholar 

Mayer ML, Westbrook GL. Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neurones. J Physiol. 1987;394:501–27.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ascher P, Nowak L. The role of divalent cations in the N-methyl-D-aspartate responses of mouse central neurones in culture. J Physiol. 1988;399:247–66.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Bourne HR, Nicoll R. Molecular machines integrate coincident synaptic signals. Cell. 1993;72:65–75.

Article  PubMed  Google Scholar 

Paoletti P, Bellone C, Zhou Q. NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease. Nat Rev Neurosci. 2013;14:383–400.

Article  PubMed  CAS  Google Scholar 

Attwell D, Gibb A. Neuroenergetics and the kinetic design of excitatory synapses. Nat Rev Neurosci. 2005;6:841–9.

Article  PubMed  CAS  Google Scholar 

Cull-Candy S, Brickley S, Farrant M. NMDA receptor subunits: diversity, development and disease. Current Opin Neurobiol. 2001;11:327–35.

Article  CAS  Google Scholar 

Dupuis JP, Nicole O, Groc L. NMDA receptor functions in health and disease: old actor, new dimensions. Neuron. 2023;111:2312–28.

Article  PubMed  CAS  Google Scholar 

Ogden KK, Traynelis SF. New advances in NMDA receptor pharmacology. Trends Pharmacol Sci. 2011;32:726–33.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Sonkusare SK, Kaul CL, Ramarao P. Dementia of Alzheimer’s disease and other neurodegenerative disorders—memantine, a new hope. Pharmacol Res. 2005;51:1–17.

Article  PubMed  CAS  Google Scholar 

Keam SJ. Dextromethorphan/Bupropion: first approval. CNS Drugs. 2022;36:1229–38.

Article  PubMed  CAS  Google Scholar 

Hashimoto K. Rapid-acting antidepressant ketamine, its metabolites and other candidates: A historical overview and future perspective. Psychiatry Clin Neurosci. 2019;73:613–27.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ahmed H, Haider A, Ametamey SM. N-Methyl-D-Aspartate (NMDA) receptor modulators: a patent review (2015-present). Expert Opin Ther Pat. 2020;30:743–67.

Article  PubMed  CAS  Google Scholar 

Strong KL, Jing Y, Prosser AR, Traynelis SF, Liotta DC. NMDA receptor modulators: an updated patent review (2013 – 2014). Expert Opin Ther Pat. 2014;24:1349–66.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Sugihara H, Moriyoshi K, Ishii T, Masu M, Nakanishi S. Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing. Biochem Biophys Res Commun. 1992;185:826–32.

Article  PubMed  CAS  Google Scholar 

Horak M, Wenthold RJ. Different roles of C-terminal cassettes in the trafficking of full-length NR1 subunits to the cell surface. J Biol Chem. 2009;284:9683–91.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Moriyoshi K, Masu M, Ishii T, Shigemoto R, Mizuno N, Nakanishi S. Molecular cloning and characterization of the rat NMDA receptor. Nature. 1991;354:31–7.

Article  PubMed  CAS  Google Scholar 

Ritter LM, Vazquez DM, Meador-Woodruff JH. Ontogeny of ionotropic glutamate receptor subunit expression in the rat hippocampus. Brain Res Dev Brain Res. 2002;139:227–36.

Article  PubMed  CAS  Google Scholar 

Monyer H, Burnashev N, Laurie DJ, Sakmann B, Seeburg PH. Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron. 1994;12:529–40.

Article  PubMed  CAS  Google Scholar 

Watanabe M, Inoue Y, Sakimura K, Mishina M. Developmental changes in distribution of NMDA receptor channel subunit mRNAs. Neuroreport. 1992;3:1138–40.

Article  PubMed  CAS  Google Scholar 

Akazawa C, Shigemoto R, Bessho Y, Nakanishi S, Mizuno N. Differential expression of five N-methyl-D-aspartate receptor subunit mRNAs in the cerebellum of developing and adult rats. J Comp Neurol. 1994;347:150–60.

Article  PubMed  CAS  Google Scholar 

Murillo A, Navarro AI, Puelles E, Zhang Y, Petros TJ, Pérez-Otaño I. Temporal dynamics and neuronal specificity of Grin3a expression in the mouse forebrain. Cereb Cortex. 2021;31:1914–26.

Article  PubMed  Google Scholar 

Sucher NJ, Akbarian S, Chi CL, Leclerc CL, Awobuluyi M, Deitcher DL, et al. Developmental and regional expression pattern of a novel NMDA receptor-like subunit (NMDAR-L) in the rodent brain. J Neurosci. 1995;15:6509–20.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ciabarra AM, Sullivan JM, Gahn LG, Pecht G, Heinemann S, Sevarino KA. Cloning and characterization of chi-1: a developmentally regulated member of a novel class of the ionotropic glutamate receptor family. J Neurosci. 1995;15:6498–508.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Wong HK, Liu XB, Matos MF, Chan SF, Pérez-Otaño I, Boysen M, et al. Temporal and regional expression of NMDA receptor subunit NR3A in the mammalian brain. J Comp Neurol. 2002;450:303–17.

Article  PubMed  CAS  Google Scholar 

Wee KSL, Zhang Y, Khanna S, Low CM. Immunolocalization of NMDA receptor subunit NR3B in selected structures in the rat forebrain, cerebellum, and lumbar spinal cord. J Comp Neurol. 2008;509:118–35.

Article  PubMed  CAS  Google Scholar 

Fukaya M, Hayashi Y, Watanabe M. NR2 to NR3B subunit switchover of NMDA receptors in early postnatal motoneurons. Eur J Neurosci. 2005;21:1432–6.

Article  PubMed