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Evaluation of pulmonary hypertension in heart failure with preserved ejection fraction
Evaluation of pulmonary hypertension in heart failure with preserved ejection fraction
In contemporary clinical practice, pulmonary hypertension (PH) is most commonly caused by heart failure with preserved eje...
Cardiac rehabilitation in patients with heart failure: clinical recommendation based on a review of the evidence
Cardiac rehabilitation in patients with heart failure: clinical recommendation based on a review of the evidence
Cardiac rehabilitation (CR) is a comprehensive, multidisciplinary approach that combines exercise training, risk factor ma...
Heart failure and left ventricular ejection fraction: a necessary but imperfect partnership
Heart failure and left ventricular ejection fraction: a necessary but imperfect partnership
The left ventricular ejection fraction (LVEF) is the most commonly used index to assess left ventricular systolic function...
Diabetic cardiomyopathy: Mechanistic insights on molecular pathways and emerging therapeutic approaches
Diabetic cardiomyopathy: Mechanistic insights on molecular pathways and emerging therapeutic approaches
Diabetes and its complications represent a global burden to human health. Among diabetic microvascular and macrovascular c...
Phenotype-guided approach for device-based therapies in heart failure
Phenotype-guided approach for device-based therapies in heart failure
Device-based therapies have become integral in the management of heart failure (HF). By targeting structural or neurohormo...
Navigating heart failure: a plain-language summary to empower people with heart failure
Navigating heart failure: a plain-language summary to empower people with heart failure
Heart failure is a chronic condition that can result from multiple causes and occurs when the heart cannot pump enough blo...
Heart failure and chronic obstructive pulmonary disease. A combination not to be underestimated
Heart failure and chronic obstructive pulmonary disease. A combination not to be underestimated
Chronic obstructive pulmonary disease (COPD) and heart failure (HF) frequently coexist and interact through complex and bi...
Echocardiographic monitoring in cancer therapy: clinical guidance for cardiologists and oncologists
Echocardiographic monitoring in cancer therapy: clinical guidance for cardiologists and oncologists
Transthoracic echocardiography has a central role in the diagnosis and monitoring of cancer therapy-related cardiac dysfun...
Redefining endpoints in heart failure clinical trials: the emerging role of wearable technologies in contemporary trial design
Redefining endpoints in heart failure clinical trials: the emerging role of wearable technologies in contemporary trial design
Randomised controlled trials (RCTs) in heart failure (HF) have progressively broadened their primary endpoints over recent...
Management of arrhythmias in left ventricular assist device recipients
Management of arrhythmias in left ventricular assist device recipients
Left ventricular assist device (LVAD) implantation is an important surgical option for patients with advanced heart failur...
Heart failure with preserved ejection fraction, from pathophysiology to technology tools aim improve patients’ management
Heart failure with preserved ejection fraction, from pathophysiology to technology tools aim improve patients’ management
Heart failure with preserved ejection fraction (HFpEF) accounts for nearly 50% of all heart failure cases and remains a si...
Do I really need to be admitted? A case for more outpatient therapies for acute decompensated heart failure
Do I really need to be admitted? A case for more outpatient therapies for acute decompensated heart failure
Loop diuretics remain the mainstay of decongestion therapy. Still, their effectiveness can be reduced by inadequate dosing...
Atrial shunt therapy for heart failure: an update review
Atrial shunt therapy for heart failure: an update review
Interatrial shunt devices (IASDs) and implant-free strategies have emerged as novel approaches for heart failure (HF) mana...
Toward next-generation BNP/NT-proBNP biosensors: multiplexed detection, biofouling control, and digital health integration
Toward next-generation BNP/NT-proBNP biosensors: multiplexed detection, biofouling control, and digital health integration
In the past five years, rapid progress has been made in biosensor platforms for BNP and NT-proBNP detection. Innovations s...
Evolving role of echocardiography across the heart failure spectrum: from prevention to advanced management
Evolving role of echocardiography across the heart failure spectrum: from prevention to advanced management
Heart failure (HF) is a global health burden that progresses through identifiable stages from at-risk individuals to sympt...
Hemodynamic characteristics of dilated ascending aorta in patients with bicuspid aortic valve
Hemodynamic characteristics of dilated ascending aorta in patients with bicuspid aortic valve
The aim of this study is to investigate the influence of aortic diameter on hemodynamic environment characteristics in pat...
Positron emission tomography in cardiac amyloidosis: current evidence and future directions
Positron emission tomography in cardiac amyloidosis: current evidence and future directions
The increasing recognition of cardiac amyloidosis (CA) as a cause of heart failure, coupled with advancements in therapeut...
Effects of anti-inflammatory therapy in acute heart failure: a systematic review and meta-analysis
Effects of anti-inflammatory therapy in acute heart failure: a systematic review and meta-analysis
We examined current evidence regarding the effects of anti-inflammatory therapies in patients with acute heart failure (AH...
Tricuspid regurgitation after heart transplantation: where innovation and intervention are in hibernation
Tricuspid regurgitation after heart transplantation: where innovation and intervention are in hibernation
Tricuspid regurgitation (TR) is a common valvular dysfunction following heart transplantation (HT), with reported prevalen...
Closing the GDMT gap: insights from PHARM-HF A&F on the role of pharmacists in heart failure care
Closing the GDMT gap: insights from PHARM-HF A&F on the role of pharmacists in heart failure care
This focused review examines the results of the PHARM-HF A&F Study, a randomized trial evaluating audit and feedba...
Worsening heart failure: progress, pitfalls, and perspectives
Worsening heart failure: progress, pitfalls, and perspectives
For most patients with chronic heart failure (HF), the clinical course of the disease includes periods of apparent clinica...
Emerging, novel gene-modulating therapies for transthyretin amyloid cardiomyopathy
Emerging, novel gene-modulating therapies for transthyretin amyloid cardiomyopathy
Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive, life-threatening disease caused by the pathological depos...
Cirrhotic cardiomyopathy: comprehensive insights into pathophysiology, diagnosis, and management
Cirrhotic cardiomyopathy: comprehensive insights into pathophysiology, diagnosis, and management
Cirrhotic cardiomyopathy (CCM) is a cardiac dysfunction linked to chronic liver disease, primarily characterized by impair...
Mechanisms of exercise intolerance in heart failure with preserved ejection fraction (HFpEF)
Mechanisms of exercise intolerance in heart failure with preserved ejection fraction (HFpEF)
Exercise intolerance is a well-established symptom of heart failure with preserved ejection fraction (HFpEF) and is associ...
Leptin and heart failure: the chicken or the egg?
Leptin and heart failure: the chicken or the egg?
Leptin plays a dual role in heart failure (HF), acting as either a primary driver or a secondary phenomenon depending on t...