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Emerging Therapeutics in Rheumatoid Arthritis
Emerging Therapeutics in Rheumatoid Arthritis
Current rheumatoid arthritis (RA) treatment guidelines recommend a treat-to-target approach with a goal of remission or lo...
Still’s Disease and Autoinflammation: Positioning an Inflammatory Syndrome on the Autoinflammation-Autoimmunity Spectrum
Still’s Disease and Autoinflammation: Positioning an Inflammatory Syndrome on the Autoinflammation-Autoimmunity Spectrum
Still’s disease exemplifies systemic inflammatory disorders existing on a continuum between autoinflammation and aut...
NOD2-Related Multisystem Inflammatory Disorders and Recent Advances
NOD2-Related Multisystem Inflammatory Disorders and Recent Advances
Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is an intracellular innate immune sensor. Its functi...
Mechanistic Insights from Human Studies in Axial Spondyloarthritis: A T Cell Story
Mechanistic Insights from Human Studies in Axial Spondyloarthritis: A T Cell Story
Ankylosing spondylitis (AS) represents the archetype of the spondyloarthritis family defined by its strong association wit...
Correction: Emerging Therapeutics in Rheumatoid Arthritis
Correction: Emerging Therapeutics in Rheumatoid Arthritis
Correction to: Current Rheumatology Reports (2026) 28:2In the original version of thi...
Management of Takayasu Arteritis – A 2026 Update
Management of Takayasu Arteritis – A 2026 Update
Takayasu arteritis (TAK) is a chronic, large-vessel vasculitis disproportionately affecting young women. The consequences ...
Is Gout an Autoinflammatory Disease?
Is Gout an Autoinflammatory Disease?
This review recognizes gout as an autoinflammatory disease rather than a solely metabolic condition. It provides an overvi...
Treat-to-Target Urate-lowering Therapy: Lessons Learned from the STOP Gout Study
Treat-to-Target Urate-lowering Therapy: Lessons Learned from the STOP Gout Study
The purpose of this review is to provide details of the STOP Gout trial, among the first randomized, blinded studies to co...
Care of the Patient with Interstitial Lung Disease Perioperatively
Care of the Patient with Interstitial Lung Disease Perioperatively
Patients with interstitial lung disease (ILD) are at elevated risk of postoperative pulmonary complications (PPCs), includ...
Correction to: Is Gout and Autoinflammatory Disease?
Correction to: Is Gout and Autoinflammatory Disease?
Correction to: Information Systems FrontiersIn this article the legend for Fig. 2 and Fig. 2 itself are incorrect, and sho...
The Role of Musculoskeletal Ultrasound in Psoriatic Arthritis: From Preclinical Detection to Treatment Monitoring
The Role of Musculoskeletal Ultrasound in Psoriatic Arthritis: From Preclinical Detection to Treatment Monitoring
Psoriatic arthritis (PsA) is a chronic, immune-mediated inflammatory disease with highly heterogeneous clinical manifestat...
Intensive Care Management of ANCA-associated Vasculitides: a Narrative Review
Intensive Care Management of ANCA-associated Vasculitides: a Narrative Review
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides, particularly granulomatosis with polyangiitis and mic...
Type I Interferonopathies: Fifteen Years On, From Concept to Therapeutic Perspectives
Type I Interferonopathies: Fifteen Years On, From Concept to Therapeutic Perspectives
Fifteen years after the initial description of type I interferonopathies, this review aims to provide an updated overview ...
Adjunctive glucocorticoids in Kawasaki disease
In a phase III trial, the addition of glucocorticoids to standard therapy did not prevent the development of coronary arte...
Lytic cell death turns TRIM21 into an autoantigen
Findings show that lytic cell death releases TRIM21, promoting immune complex uptake by macrophages and autoimmune inflamm...
Treatment strategies in giant cell arteritis and polymyalgia rheumatica: beyond glucocorticoids
Treatment strategies in giant cell arteritis and polymyalgia rheumatica: beyond glucocorticoids
Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are closely related chronic inflammatory conditions. Glucocort...
Treat-to-target in Behçet syndrome
Treat-to-target in Behçet syndrome
Behçet syndrome is a complex systemic immune-mediated form of vasculitis characterized by diverse clinical manifestat...
Decoding variants of uncertain significance in systemic autoinflammatory diseases
Decoding variants of uncertain significance in systemic autoinflammatory diseases
The development and implementation of genetic testing has revolutionized the diagnostic landscape of autoinflammatory dise...
Type I interferon mediates autoimmune photosensitivity
A study provides insights into the mechanisms that underlie photosensitivity in cutaneous lupus erythematosus and dermatom...
Rethinking early-stage knee osteoarthritis beyond radiography
Rethinking early-stage knee osteoarthritis beyond radiography
Symptomatic knee osteoarthritis at an early structural stage could provide a window of opportunity for intervention. Sympt...
The evolving comorbidity landscape of rheumatoid arthritis
The evolving comorbidity landscape of rheumatoid arthritis
Rheumatoid arthritis (RA) is associated with a wide spectrum of comorbidities that substantially influence quality of life...
Investigating the Impact of Sex on Outcomes in Juvenile Idiopathic Arthritis
Investigating the Impact of Sex on Outcomes in Juvenile Idiopathic Arthritis
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...