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Supraspinatus Muscle Degeneration, Inflammation, and Regeneration Vary By Location in a Rat Model of Severe Rotator Cuff Tear
Supraspinatus Muscle Degeneration, Inflammation, and Regeneration Vary By Location in a Rat Model of Severe Rotator Cuff Tear
Degeneration of the human supraspinatus muscle after rotator cuff tendon tear varies by location within the muscle; howeve...
Phytochemical-Mediated Green Synthesis of ZnO–CuO Nanoparticles from Stem Fibers: Structural, Thermal, and Antibacterial Characterization
Phytochemical-Mediated Green Synthesis of ZnO–CuO Nanoparticles from Stem Fibers: Structural, Thermal, and Antibacterial Characterization
The development of sustainable nanomaterials using plant-derived resources has gained increasing attention for biomedical ...
Effect of Silica-Collagen-Hydroxyapatite Biocomposite Alone and in Conjunction with Homologous Platelet Rich Plasma for the Management of Calvarial Defect in Rat Models
Effect of Silica-Collagen-Hydroxyapatite Biocomposite Alone and in Conjunction with Homologous Platelet Rich Plasma for the Management of Calvarial Defect in Rat Models
This study was aimed to investigate the bone healing efficacy of a novel biomaterial silica-collagen-hydroxyapatite compos...
Tailoring Properties of Small-Diameter Vascular Grafts: An In Vivo Study of Polycaprolactone and Polylactic Acid Blends and Copolymers
Tailoring Properties of Small-Diameter Vascular Grafts: An In Vivo Study of Polycaprolactone and Polylactic Acid Blends and Copolymers
The increasing prevalence of cardiovascular diseases has heightened the demand for effective small-diameter vascular prost...
Hydrogel Dressings for Wound Protection under Extreme Conditions: Design, Challenges, and Applications
Hydrogel Dressings for Wound Protection under Extreme Conditions: Design, Challenges, and Applications
Wound healing in extreme environments—such as high temperature, humidity, salinity, intense sunlight, and radiation&...
Synergistic Effects of Kerecis Fish-Skin Dermal Scaffold and Stromal Vascular Fraction (mSVF)
Synergistic Effects of Kerecis Fish-Skin Dermal Scaffold and Stromal Vascular Fraction (mSVF)
Chronic wounds impose a large socio-economic burden on both patients and healthcare providers. They result from altered ce...
Mitochondrial Network Enhancing (MiNE) Nanoparticles for the Treatment of Neurodegenerative Disease and the Aging Brain
Mitochondrial Network Enhancing (MiNE) Nanoparticles for the Treatment of Neurodegenerative Disease and the Aging Brain
There is a current surge in the global occurrence of neurodegenerative diseases (ND), a collection of age-related diseases...
Tracheal Reconstruction Using Hybrid Decellularized-PCL Scaffolds: Two-Stage Heterotopic and Orthotopic Transplantation
Tracheal Reconstruction Using Hybrid Decellularized-PCL Scaffolds: Two-Stage Heterotopic and Orthotopic Transplantation
Long-segment tracheal defects remain a significant surgical challenge that cannot be treated with conventional tracheal re...
Transforming Growth Factor Beta 1, Ca15-3, and Serum Retinol Levels as Biomarkers of Disease Progression in Diabetic Nephropathy Associated with Type 2 Diabetes Mellitus
Transforming Growth Factor Beta 1, Ca15-3, and Serum Retinol Levels as Biomarkers of Disease Progression in Diabetic Nephropathy Associated with Type 2 Diabetes Mellitus
This study investigated the association of transforming growth factor-beta 1 (TGF-β1), cancer antigen 15 −...
A Comprehensive Review of Polymeric Materials and Scaffold Technologies in 3D Bioprinting for Bone Tissue Engineering
A Comprehensive Review of Polymeric Materials and Scaffold Technologies in 3D Bioprinting for Bone Tissue Engineering
Bone Tissue Engineering focuses on developing biomaterials and regenerative strategies to repair bone defects and restore ...
Novel Extraction Method of BIS-GMA Resin Free Latex from (Jackfruit) and its Biomedical Applications
Novel Extraction Method of BIS-GMA Resin Free Latex from (Jackfruit) and its Biomedical Applications
Artocarpus (A.) heterophyllus is a member of the Moraceae family, all parts of which contain sticky white latex produced b...
Kartogenin-loaded Decellularized Wharton’s Jelly for the Chondrogenic Differentiation of Mesenchymal Stem Cells; An In Vitro Study
Kartogenin-loaded Decellularized Wharton’s Jelly for the Chondrogenic Differentiation of Mesenchymal Stem Cells; An In Vitro Study
In the present in vitro study, decellularized Wharton’s jelly (dWJ) scaffolds were loaded with kartogenin (KGN), and...
Nanoparticles and Nanomaterials for Targeted Drug Delivery: An Updated Review
Nanoparticles and Nanomaterials for Targeted Drug Delivery: An Updated Review
Typical drug administration methods are often limited by low bioavailability, lack of specificity in biodistribution, rapi...
Deferoxamine and Mesenchymal Cells along with Acellular Bone Graft Improved Vascularization Marker and Bone Regeneration in Radius Critical-Size Defect of Rat
Deferoxamine and Mesenchymal Cells along with Acellular Bone Graft Improved Vascularization Marker and Bone Regeneration in Radius Critical-Size Defect of Rat
Critical-sized bone defects do not heal spontaneously and remain a major clinical challenge. Strategies that simultaneousl...
Bone Marrow Mesenchymal Stem Cell Preconditioning With Alpha Pinene Reverses Ischemia Induced Neuronal Degeneration in Rats
Bone Marrow Mesenchymal Stem Cell Preconditioning With Alpha Pinene Reverses Ischemia Induced Neuronal Degeneration in Rats
Preconditioned stem cells may offer a promising approach to treat various neurological disorders. Compounds like alpha pin...
Extracellular Vesicles-Loaded Silk Fibroin Scaffolds for Targeted Therapeutic Delivery
Extracellular Vesicles-Loaded Silk Fibroin Scaffolds for Targeted Therapeutic Delivery
Extracellular vesicles (EVs), are nanovesicles with a complex composition of lipids, proteins, and nucleic acids. These ve...
Regional SDF-1α Delivery to Injured Rotator Cuff Muscle Causes Localized Changes in Inflammatory Cell Response
Regional SDF-1α Delivery to Injured Rotator Cuff Muscle Causes Localized Changes in Inflammatory Cell Response
Following rotator cuff tendon injury, the corresponding muscle undergoes degeneration, which has been found to occur asymm...
Passage-Dependent Shifts in the Immunomodulatory and Migratory Properties of Mesenchymal Stem Cell Secretomes in THP-1 Monocytic Cells
Passage-Dependent Shifts in the Immunomodulatory and Migratory Properties of Mesenchymal Stem Cell Secretomes in THP-1 Monocytic Cells
Mesenchymal stem cells (MSCs) exert immunomodulatory and regenerative effects primarily through their secretome, which com...
Targeting Molecular Dysregulation in Diabetic Wound Healing through Nanomaterial-Based Drug Delivery Systems for Improved Therapeutic Outcomes
Targeting Molecular Dysregulation in Diabetic Wound Healing through Nanomaterial-Based Drug Delivery Systems for Improved Therapeutic Outcomes
Diabetic foot ulcers (DFUs) are a serious complication of diabetes mellitus, which is marked by dysfunctional angiogenesis...
Biocompatible Titania for Drug Delivery and Tissue Engineering
Biocompatible Titania for Drug Delivery and Tissue Engineering
Titanium dioxide (TiO2) has garnered significant attention in biomedical applications, particularly in drug delivery and t...
Combining Surface Modification and Bioactive Cues to Enhance Medpor® Implant Integration
Combining Surface Modification and Bioactive Cues to Enhance Medpor® Implant Integration
Achieving stable and functional integration of synthetic implants with host tissue remains a key challenge in tissue engin...
Neutral Buoyancy as a Simple Approach to Simulated Microgravity
Neutral Buoyancy as a Simple Approach to Simulated Microgravity
It is well recognized that interesting biological phenomena occur in various organisms in microgravity. However, real micr...
Therapeutic Efficacy of Mesenchymal Stem Cells (MSCs) on Alzheimer’s Disease: Review of Clinical Results
Therapeutic Efficacy of Mesenchymal Stem Cells (MSCs) on Alzheimer’s Disease: Review of Clinical Results
Alzheimer's disease (AD) presents significant unmet medical needs with no effective therapeutic options. Current pharm...
Umbilical Cord Mesenchymal Stem Cells and Wnt Pathway Modulation: A Novel Therapy for Liver Cirrhosis and Steatosis
Umbilical Cord Mesenchymal Stem Cells and Wnt Pathway Modulation: A Novel Therapy for Liver Cirrhosis and Steatosis
The Wnt signalling pathway, one of the key classical stem cell pathways, plays an important role in helping the liver rege...
Polydeoxyribonucleotide (PDRN) in Dentistry: Narrative Review for Mechanisms and Emerging Clinical Applications
Polydeoxyribonucleotide (PDRN) in Dentistry: Narrative Review for Mechanisms and Emerging Clinical Applications
Polydeoxyribonucleotide (PDRN) has emerged as a promising and cost-effective biological agent in regenerative medicine due...
Transcriptomic Profiling Reveals Mechanisms of Anoikis Resistance in Spheroid-Cultured Human Umbilical Cord Mesenchymal Stem Cells
Transcriptomic Profiling Reveals Mechanisms of Anoikis Resistance in Spheroid-Cultured Human Umbilical Cord Mesenchymal Stem Cells
Mesenchymal stem (stromal) cells are a promising cell source for regenerative medicine, but their therapeutic efficacy is ...
Human Amniotic Mesenchymal Stromal Cells Promote Bone Regeneration via Regulating Ameloblastoma-Derived-Bone Marrow Mesenchymal Cells Crosstalk and Autophagy in Ameloblastoma Microenvironment
Human Amniotic Mesenchymal Stromal Cells Promote Bone Regeneration via Regulating Ameloblastoma-Derived-Bone Marrow Mesenchymal Cells Crosstalk and Autophagy in Ameloblastoma Microenvironment
Growing evidence validates the vital function of mesenchymal stem cells (MSCs) in tumor development. Our previous findings...
Dual-Drug Stent with Sirolimus and WKYMVm Promotes Endothelialization and Limits Hyperplasia
Dual-Drug Stent with Sirolimus and WKYMVm Promotes Endothelialization and Limits Hyperplasia
Conventional drug-eluting stents suppress neointimal hyperplasia but delay re-endothelialization, raising long-term safety...
Human Subcutaneous Derived Stromal Vascular Fraction Endothelial Cells Display Venous and Arterial Markers in Culture and 3D Capillaries
Human Subcutaneous Derived Stromal Vascular Fraction Endothelial Cells Display Venous and Arterial Markers in Culture and 3D Capillaries
The Stromal Vascular Fraction (SVF) derived from human subcutaneous fat has attracted pivotal interest in clinical applica...
Therapeutic Effects of N-Acetylcysteine-Primed, Iron Oxide Nanoparticle-Enhanced Mesenchymal Stem Cell Exosomes in Ototoxicity Hearing Loss
Therapeutic Effects of N-Acetylcysteine-Primed, Iron Oxide Nanoparticle-Enhanced Mesenchymal Stem Cell Exosomes in Ototoxicity Hearing Loss
Sensorineural hearing loss caused by ototoxic agents remains irreversible due to the limited regenerative capacity of coch...
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