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Psychosocial adversity captured by ICD-10 Z-codes and mortality risk: evidence from the UK Biobank
Psychosocial adversity captured by ICD-10 Z-codes and mortality risk: evidence from the UK Biobank
Psychosocial adversity is a major determinant of health, but the mortality associations of its clinical documentation via ...
Telomere length and appendicular lean mass over six years in older adults with overweight or obesity and metabolic syndrome: a prospective cohort study
Telomere length and appendicular lean mass over six years in older adults with overweight or obesity and metabolic syndrome: a prospective cohort study
Telomere length (TL) has been proposed as a marker of appendicular lean mass (ALM) decline; however, longitudinal...
Resting heart rate and cognitive function in ageing: Insights from a secondary data analysis
Resting heart rate and cognitive function in ageing: Insights from a secondary data analysis
Resting heart rate (RHR) is an accessible measure that may reflect age-related cardiovascular and autonomic dysregulation ...
Age-related metabolomic signatures and stroke susceptibility in a population-based cohort
Age-related metabolomic signatures and stroke susceptibility in a population-based cohort
Aging-related metabolic dysregulation and vascular vulnerability contribute substantially to stroke susceptibility, yet su...
Association between atrial fibrillation and systemic inflammation with muscle mass and strength trajectories in old age
Association between atrial fibrillation and systemic inflammation with muscle mass and strength trajectories in old age
The long-term impact of atrial fibrillation (AF) and systemic inflammation on muscle health and, hence, functional decline...
Space radiation and microgravity as models of accelerated aging: modulation of hepatic miRNA-TGF-β networks associated with senescence and fibrosis
Space radiation and microgravity as models of accelerated aging: modulation of hepatic miRNA-TGF-β networks associated with senescence and fibrosis
Future deep-space missions will expose astronauts to microgravity and ionizing radiation, which induce molecular changes t...
Machine learning derived abdominal aortic calcification is associated with physical frailty in community-dwelling adults: the UK Biobank Imaging Study
Machine learning derived abdominal aortic calcification is associated with physical frailty in community-dwelling adults: the UK Biobank Imaging Study
Clinical cardiovascular disease (CVD) is often present in frail individuals. However, it remains unclear whether subclinic...
Exploring the association between common genetic deletions and aging: insights from the Canadian Longitudinal Study on Aging
Exploring the association between common genetic deletions and aging: insights from the Canadian Longitudinal Study on Aging
Germline deletions of UDP-glycosyltransferase (UGT) UGT2B17 and UGT2B28 genes are common in human populations, yet their a...
Exploratory plasma metabolomics of aging-related associations with muscle quality and pulmonary function
Exploratory plasma metabolomics of aging-related associations with muscle quality and pulmonary function
Aging is accompanied by metabolic alterations that may precede or parallel functional decline. While chronological age cor...
Associations of daily step counts with cognitive, clinical, and resting-state electroencephalographic measures in patients with cognitive decline due to Alzheimer’s disease
Associations of daily step counts with cognitive, clinical, and resting-state electroencephalographic measures in patients with cognitive decline due to Alzheimer’s disease
Sedentary behavior is a recognized and modifiable risk factor for cognitive decline and dementia across neurodegenerative ...
Age-adjusted leukocyte telomere length predicts long-term mortality in older patients discharged from acute care hospitals
Age-adjusted leukocyte telomere length predicts long-term mortality in older patients discharged from acute care hospitals
Leukocyte telomere length (LTL) is a widely studied biomarker of biological aging, reflecting cumulative cellular damage b...
Unraveling physical performance over time in hospitalized older patients with walking limitation: the role of ultrasound-derived vastus lateralis muscle thickness
Unraveling physical performance over time in hospitalized older patients with walking limitation: the role of ultrasound-derived vastus lateralis muscle thickness
Acute hospitalization is a critical stressor that often leads to functional decline in older patients, highlighting the ne...
Gut microbiota profiles across intrinsic capacity strata in community-dwelling older adults using full-length 16S rRNA sequencing
Gut microbiota profiles across intrinsic capacity strata in community-dwelling older adults using full-length 16S rRNA sequencing
Intrinsic capacity (IC), introduced by the World Health Organization, provides a multidimensional framework for evaluating...
Quantitative Cellular AGing Evaluation system (qCAGEs): a dual-parameter platform for high-throughput senescence screening
Quantitative Cellular AGing Evaluation system (qCAGEs): a dual-parameter platform for high-throughput senescence screening
Accurate identification and quantification of senescence-modulating compounds require screening platforms that can disting...
Plasma proteins associated with disability and mortality risks in Japanese community-dwelling octogenarians
Plasma proteins associated with disability and mortality risks in Japanese community-dwelling octogenarians
Japan has one of the world’s longest life expectancies, yet biomarkers associated with disability and mortality in v...
The shaky voice of aging localized to the larynx: dissociation of frequency and amplitude tremor
The shaky voice of aging localized to the larynx: dissociation of frequency and amplitude tremor
Aging is associated with structural and functional changes of the vocal folds that may result in presbyphonia, often perce...
Study protocol for FAXAge: a randomized, controlled clinical trial of fasting and exercise to slow aging in humans
Study protocol for FAXAge: a randomized, controlled clinical trial of fasting and exercise to slow aging in humans
Biomarkers of aging, particularly DNA methylation-based clocks, have shown promise as tools to assess whether intervention...
Long-term intake of statins or renin-angiotensin system inhibitors: associations with sarcopenia-related parameters in older people
Long-term intake of statins or renin-angiotensin system inhibitors: associations with sarcopenia-related parameters in older people
The long-term impact of common cardiovascular medications on sarcopenia in older people is unclear. The objective was to i...
Age-related differences in motor unit discharge rate modulation across contraction levels
Age-related differences in motor unit discharge rate modulation across contraction levels
Age-related strength loss may reflect morphological and neural adaptations that differ between muscles. However, it is unc...
The influence of aging on graded peripheral venous return and complex blood flow features through human veins
The influence of aging on graded peripheral venous return and complex blood flow features through human veins
Aging is associated with reduced venous compliance and altered muscle pump function, though how these features impact veno...
Usability Insights From Nursing Home Residents On a New Hip Protector Design in Singapore: a Feasibility Study
Usability Insights From Nursing Home Residents On a New Hip Protector Design in Singapore: a Feasibility Study
Older adults residing in nursing homes face an increased risk of falls leading to hip fractures, resulting in a reduced qu...
Using Welfare Technology To Increase Activity in Nursing Homes: Effects of the ‘Touch & Play’ Activity Screen for People with a Diagnosis of Dementia
Using Welfare Technology To Increase Activity in Nursing Homes: Effects of the ‘Touch & Play’ Activity Screen for People with a Diagnosis of Dementia
This study evaluated the effectiveness of the Touch & Play interactive activity screen as welfare technology to en...
Exploring Ageism and Age Norms among Older Adults in Urban India
Exploring Ageism and Age Norms among Older Adults in Urban India
The UN Decade of Healthy Ageing plan of action has identified combating ageism and challenging negative and restrictive at...
Accessing the Hard and Soft Infrastructure of Residential Care Services for Older Adults in Japan: Implications for Post-Growth East Asia
Accessing the Hard and Soft Infrastructure of Residential Care Services for Older Adults in Japan: Implications for Post-Growth East Asia
Globally, populations are getting older. Japan is at the forefront of addressing the challenges posed by population ageing...
Social Networks and Mental Health: A Study of Older Adults in Rural Bihar, India
Social Networks and Mental Health: A Study of Older Adults in Rural Bihar, India
With record high population growth in India, the number of older adults has significantly increased. In Bihar (a state in ...
Bodily Disconnection in Older Adults Residing in Nursing Homes: The Relationship between Bodily Disconnection, Depressive Symptoms and Meaning in Life
Bodily Disconnection in Older Adults Residing in Nursing Homes: The Relationship between Bodily Disconnection, Depressive Symptoms and Meaning in Life
To examine the relationship between bodily disconnection and two indicators of late life well-being – depressive sym...
Spanish Electronic and Paper Version of the Comprehensive Frailty Assessment Instrument (CFAI): a Cross-Cultural Adaptation
Spanish Electronic and Paper Version of the Comprehensive Frailty Assessment Instrument (CFAI): a Cross-Cultural Adaptation
Frailty is a dynamic and potentially reversible state that precedes and predicts adverse health outcomes. However, there i...
Factors Affecting ICT Access and Use of Older Adults and Caregivers in the State of Qatar
Factors Affecting ICT Access and Use of Older Adults and Caregivers in the State of Qatar
Despite the growing importance of the older population in the Arab region, initiatives to facilitate their Information and...
Effect of Multimodal Cognitive Intervention in Older Adults with Mild Cognitive Impairment: A Meta-analysis of Randomized Controlled Trials
Effect of Multimodal Cognitive Intervention in Older Adults with Mild Cognitive Impairment: A Meta-analysis of Randomized Controlled Trials
Nonpharmacological interventions benefit individuals with mild cognitive impairment (MCI), but the synergistic benefits of...
The Validity of Measures in Specific Training According to BaLance Evaluation (STABLE) – An Exercise-based Approach to Balance Rehabilitation for Older Adults at Risk of Falling
The Validity of Measures in Specific Training According to BaLance Evaluation (STABLE) – An Exercise-based Approach to Balance Rehabilitation for Older Adults at Risk of Falling
Falls are a leading cause of injury and premature death among older adults. Specific Training According to BaLance Evaluat...
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