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[Developmental Biology] Collective Cell Migration Strategies: Patterning, Motility, and Directionality of the Posterior Lateral Line Primordium in Zebrafish
A new type of review journal, featuring comprehensive collections of expert review articles on important topics in the mol...
[Cell Biology] Ca2+ Fluxes across Membrane Contact Sites
A new type of review journal, featuring comprehensive collections of expert review articles on important topics in the mol...
[Molecular Biology] Mechanisms and Determinants of -1 Ribosome Frameshifting and Bypassing
A new type of review journal, featuring comprehensive collections of expert review articles on important topics in the mol...
Adipose-Derived Proinflammatory Visfatin Promotes Vascular Calcification via TLR4 and is Suppressed by Empagliflozin
Adipose-Derived Proinflammatory Visfatin Promotes Vascular Calcification via TLR4 and is Suppressed by Empagliflozin
Vascular calcification, a common complication of metabolic diseases such as diabetes and obesity, is closely associated wi...
Dendritic Cells Derived MMP9 Fuels Sepsis-Induced Cardiac Dysfunction Through JNK/AP1 Driven Pro-Inflammatory Cytokine and Nitric Oxide Storm
Dendritic Cells Derived MMP9 Fuels Sepsis-Induced Cardiac Dysfunction Through JNK/AP1 Driven Pro-Inflammatory Cytokine and Nitric Oxide Storm
Metalloproteinase9 is an important inflammatory mediator, but its contribution to sepsis-induced myocardial dysfunction (S...
The Histamine Four Receptor Regulates LFA-1 But Not Mac-1 -Dependent Neutrophil Adhesion and Inflammatory Functions
The Histamine Four Receptor Regulates LFA-1 But Not Mac-1 -Dependent Neutrophil Adhesion and Inflammatory Functions
Neutrophils incubated on ICAM-1- or fibrinogen- coated plates produced histamine in response to fMLP indicating that hista...
Peripheral Circulating Exosomes Induce Sepsis-associated Liver Injury by Up-regulating STAT1 to Promote Autophagy and Regulating the SLC7A11-GSH-GPX4 Axis to Promote Ferroptosis
Peripheral Circulating Exosomes Induce Sepsis-associated Liver Injury by Up-regulating STAT1 to Promote Autophagy and Regulating the SLC7A11-GSH-GPX4 Axis to Promote Ferroptosis
Peripheral exosomes have been implicated in the pathogenesis of multiple organ dysfunction during sepsis. However, their r...
Nrf2 Protects Against Lipoteichoic Acid-Induced Acute Lung Injury By Suppressing SLC24A2-Mediated Ferroptosis
Nrf2 Protects Against Lipoteichoic Acid-Induced Acute Lung Injury By Suppressing SLC24A2-Mediated Ferroptosis
Acute lung injury (ALI) is a severe inflammatory syndrome characterized by epithelial and endothelial injury, increased pu...
Erosion or Explosion: Integrated Single-Cell Transcriptomics Reveals Cellular Heterogeneity in Aortic Aneurysm and Dissection
Erosion or Explosion: Integrated Single-Cell Transcriptomics Reveals Cellular Heterogeneity in Aortic Aneurysm and Dissection
Aortic aneurysm (AA) and aortic dissection (AD) are life-threatening vascular diseases characterized by progressive wall d...
Inflammation starves antitumour immunity
Inflammation starves antitumour immunity
When cells sense amino acids, they activate a kinase complex known as mTORC1 in a process that can regulate cancer metabol...
RNA imbalance as a hallmark of cellular ageing
RNA imbalance as a hallmark of cellular ageing
Major advances over the past few decades have highlighted the complex regulation of RNA from transcription to nuclear expo...
High-throughput generation of patient-derived cancer stem cells for precision medicine using a microwell-chip platform
High-throughput generation of patient-derived cancer stem cells for precision medicine using a microwell-chip platform
Substantial evidence indicates that cancer stem cells (CSCs) drive breast cancer (BRC) initiation, progression, therapy re...
Tissue rigidity phase transition shapes morphogen gradients
Tissue rigidity phase transition shapes morphogen gradients
During development, local mechanochemical cues within the cell microenvironment are translated into signalling pathways th...
Fuelling basement membrane invasion
Cell invasion though the basement membranes is an energetically demanding process, but the mechanisms through which cells ...
Alu RNAs organize transcription at speckles
Nuclear speckles are gene expression nodes where transcription and RNA processing take place. Yet, the mechanisms underlyi...
Tracking the fates of cystine in tumours
Tumours can rewire their metabolism due to activation of the transcription factor NRF2. Brain, Vigil et al. explored the m...
Mechanisms and functions of large extracellular vesicle biogenesis
Mechanisms and functions of large extracellular vesicle biogenesis
Owing to the ability of extracellular vesicles (EVs) to encapsulate and transfer biomolecules for intercellular communicat...
Kinetic management of endocrine disruption: How chemical dynamics shape hormonal systems
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
FAM237B, a conserved orexigenic neuropeptide, is regulated by fasting, insulin, and neuroinflammation in mouse hypothalamic NPY/AgRP neurons
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Alpha-Klotho-deficient female mice exhibit estrogen metabolic dysregulation and a premature ovarian insufficiency–like phenotype
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
SIK1 drives lipid-induced insulin resistance in skeletal muscle by linking TGFβ1-Smad2/3 activation to PDE4-cAMP dysregulation
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
n-3 polyunsaturated fatty acids inhibit the IL-1β/SP positive feedback loop in intervertebral disc endplate and low back pain-related behaviors in mice
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Oral Honokiol-loaded solid lipid nanoparticles: A shielding nanotherapeutic strategy to attenuate STZ-induced type 1 diabetes via targeted modulation of oxidative stress and apoptotic signaling
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Corrigendum to “Differential effects of synthetic progestagens on neuron survival and estrogen neuroprotection in cultured neurons” [Mol. Cell. Endocrinol. 384 1-2 (2014) 52-60]
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Retraction notice to “Involvement of PI3 kinase and MAP kinase in IGF-I- and insulin-induced oocyte maturation in Cyprinus carpio” [Mol. Endocrinol. 309 (2009) 93-100]
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Retraction notice to “Regulation of ovarian steroidogenesis in vitro by IGF-I and insulin in common carp, Cyprinus carpio: stimulation of aromatase activity and P450arom gene expression” [Mol. Endocrinol. 315 (2010) 95-103]
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Concept and connotation of the geroprotective and anti-aging effects of metformin: From AMPK activation to SASP suppression
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
3D bioprinted connections in Liver‒Pancreas crosstalk: Lessons learned and future directions
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Gastrointestinal expression of the NPB/W signaling system and inhibitory effects of neuropeptide B and W on colonic contractility in control and diabetic rats
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Histone deacetylases inhibitor Chidamide mitigates inflammation and insulin resistance by targeting VDR in skeletal muscle cells
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
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