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Synergistic effects of herbal extracts and nanoparticles in skin damage repair: A comprehensive review
Objective: Today, applying herbal extracts to treat skin damage has become widespread and it is supported by numerous stud...
Evaluation of the effects of Asparagus racemosus extract (ARova5X) supplementation on postmenopausal discomfort
Objective: Menopause is a critical physiological transition often associated with a spectrum of health challenges such as ...
Impact of green tea on obesity-related hormones in postmenopausal women: A systematic review and meta-analysis of randomized controlled trials
Objective: Menopause leads to hormonal changes that increase visceral fat, raising risks for metabolic disorders and breas...
Therapeutic effects of Zataria multiflora Boiss. extract-loaded chitosan nanoparticles against asthma in rats
Objective: Asthma is one of the most common chronic inflammatory disorders worldwide. Zataria multiflora Boiss., widely us...
Lycopene suppresses α-cypermethrin nephrotoxicity: An insight into its modulatory effect on oxidative stress-mediated pro-inflammation, DNA damage and caspase apoptosis in Wistar rats
Objective: Cypermethrin (CPM) is a synthetic pyrethroid pesticide with ubiquitous use in agriculture, but well associated ...
Effect of hydroalcoholic extracts of Quercus brantii and Salvia officinalis on the expression of wound healing and anti-inflammatory factors in human fibroblast cells
Objective: Based on research regarding the regenerative properties of Quercus brantii in wound healing and the anti-inflam...
Beneficial effects of berberine and 6-gingerol against global cerebral ischemia: Insights from stereological, behavioral, and antioxidant enzyme activity
Objective: Global cerebral ischemia (GCI) severely impacts brain function, leading to cognitive impairments and neuronal d...
Investigation of the co-administration of flaxseed supplementation with high-intensity interval training, resistance training, or combined training on hematological indices and kidney health in fructose/CCl4-induced NAFLD in rats
Objective: Types of exercise training and flaxseed are beneficial approaches to improve non-alcoholic fatty liver disease ...
The hepatoprotective impacts of Citrullus colocynthis seeds extract on type 1 diabetes-induced liver inflammation and oxidative stress in rats: The role of nrf2/keap1 pathway
Objective: Type 1 Diabetes (T1D) induces several consequences including hepatic damage resulting from oxidative stress and...
Mistletoe extract (Iscador®) in cancer patients undergoing chemotherapy for prostate and bladder tumors: A prospective observational study
Objective: While mistletoe (a semi-parasitic evergreen plant) extract is commonly used as a complementary therapy in Europ...
The antidiabetic effects of hesperidin and piperine in streptozotocin-induced diabetic rats
Objective: Diabetes mellitus is a metabolic and chronic condition defined by increased blood glucose concentrations. The p...
Dorema aucheri extract for reducing oxidative stress and kidney injuries in diabetic rats
Objective: Diabetic hyperglycemia causes oxidative stress, contributing to chronic kidney disease (CKD). This study evalua...
The effect of curcumin-piperine supplementation on liver transient elastography and biochemical indices in patients with non-alcoholic fatty liver disease: A randomized controlled trial
Objective: Non-alcoholic fatty liver disease (NAFLD), characterized by an excessive buildup of triglycerides in hepatocyte...
Therapeutic effects of Asafoetida (Ferula foetida oleo-gum-resin) on lung function tests, clinical symptoms, and blood parameters in asthmatic patients
Objective: Asthma is a common chronic disease with a wide global prevalence. In this disease, airway inflammation causes m...
Evaluation of the preventive effect of intravenous trans-sodium crocetinate followed by oral crocetin on contrast-induced nephropathy in patients with chronic kidney disease undergoing coronary angioplasty: A randomized placebo-controlled triple-blind clinical trial
Objective: Contrast media (CM) can potentially cause nephropathy. Trans-sodium crocetinate (TSC) has shown promising antio...
Rhizophora apiculata extracts improved memory function through inhibition of acetylcholinesterase and oxidative stress in scopolamine-induced memory deficits in rats
Objective: This study aims to investigate the neuroprotective, memory enhancement effects and phytochemical profile of Rhi...
Effect of pomegranate seed supplementation on cardiometabolic parameters: A systematic review and meta-analysis of interventional studies
Objective: This systematic review and meta-analysis of interventional studies aimed to investigate cardiometabolic protect...
The efficacy of Hypericum perforatum L. for the treatment of premenstrual syndrome: A systematic review and meta-analysis
Objective: Premenstrual syndrome (PMS) occurs in the luteal phase of the menstrual cycle and is characterized by physical,...
Effect of flaxseed oil supplementation on lipid profile in adults: A systematic review and dose-response meta-analysis of randomized controlled trials
Objective: This study evaluated the effects of flaxseed oil (FO, derived from Linum usitatissimum) supplementation on lipi...
Oren-gedoku-to suppresses hypothalamic adenosine 5′-monophosphate-activated protein kinase activity and olanzapine-induced hyperglycemia
Objective: Atypical antipsychotics such as olanzapine (OLZ) are associated with elevated blood glucose levels. Owing to se...
Sophflarines F–K: matrine-based alkaloids with a rare aromatic system from and their anti-inflammatory and synergistic antibacterial effects
Sophflarines F–K: matrine-based alkaloids with a rare aromatic system from and their anti-inflammatory and synergistic antibacterial effects
Six new matrine-based alkaloids, sophflarines F–K (1–6), featuring a rare aromatic system, were obtained from ...
Artificial intelligence-based screening of phytochemicals for targeted cancer therapy
Artificial intelligence-based screening of phytochemicals for targeted cancer therapy
Cancer remains one of the leading causes of death worldwide and continues to pose a serious public health challenge. The l...
Natural monoterpenoid geraniol promotes antioxidant defense and stress tolerance via SKN-1/Nrf2 activation in
Natural monoterpenoid geraniol promotes antioxidant defense and stress tolerance via SKN-1/Nrf2 activation in
Oxidative stress (OS) is a major contributor to aging and the pathogenesis of numerous conditions, including diabetes, neu...
Prenylated acylphloroglucinols from the fruits of
Prenylated acylphloroglucinols from the fruits of
Twenty-eight prenylated acylphloroglucinols, including the new hypulatones C–F (1–4), have been isolated from ...
Diversity of oligosaccharides in lipooligosaccharides of and its anti-atherosclerotic activity
Diversity of oligosaccharides in lipooligosaccharides of and its anti-atherosclerotic activity
As an important and beneficial gut commensal, Akkermansia muciniphila plays a crucial role in regulating host metabolism a...
Cytotoxic trichothecene derivatives from sp. DWS815
Cytotoxic trichothecene derivatives from sp. DWS815
Ten novel trichothecene sesquiterpenoids including two new seco-trichothecenes, trichotheciumones A (1) and B (2), a new t...
Facile synthesis and biological evaluation of glomuferrin and rhizoferrin as ferroptosis inhibitors in rice blast disease
Facile synthesis and biological evaluation of glomuferrin and rhizoferrin as ferroptosis inhibitors in rice blast disease
Iron homeostasis has recently emerged as a key determinant in the early stages of plant–pathogen interactions, parti...
Mechanistic insights into polyphenolic constituents from traditional Chinese medicines in inhibiting colorectal cancer metastasis
Mechanistic insights into polyphenolic constituents from traditional Chinese medicines in inhibiting colorectal cancer metastasis
Colorectal cancer (CRC) is the third most predominant cancer caused by genetic, environmental and nutritional factors and ...
First total synthesis of (±)-spirobroussonin B via electromediated oxidative coupling for constructing spirodienone ring
First total synthesis of (±)-spirobroussonin B via electromediated oxidative coupling for constructing spirodienone ring
An electromediated oxidative coupling strategy for constructing spirodienone fragment has been developed and applied as th...
New patchoulol- and guaiane-type sesquiterpenoids from with anti-melanogenic activity
New patchoulol- and guaiane-type sesquiterpenoids from with anti-melanogenic activity
Twelve new sesquiterpenoids, sanguisorbaols A–L (1–12), along with twenty-five known compounds (13–37), ...
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