SCI Abstract

search
+
Exploring the Biosynthesis of Cyclic Peptide Catalyzed by the PBP-Type Thioesterase Ulm16
Exploring the Biosynthesis of Cyclic Peptide Catalyzed by the PBP-Type Thioesterase Ulm16
Cyclopeptide compounds have emerged as a significant source of drug candidates in pharmaceutical development due to their ...
Study of novel ZIF materials with dual recognition of internal and external CO and efficient CO/N separation
Study of novel ZIF materials with dual recognition of internal and external CO and efficient CO/N separation
To address the growing issue of the greenhouse effect, CO2 capture has emerged as a key area of research. In this paper, z...
Edge Ductility as Key Enabler for Design Freedom in Chassis Components
Edge Ductility as Key Enabler for Design Freedom in Chassis Components
Share this articleAnyone you share the following link with will be able to read this content:Get shareable linkSorry, a sh...
Lightweight Battery Housings – Sustainability Assessment throughout the Life Cycle
Lightweight Battery Housings – Sustainability Assessment throughout the Life Cycle
The Circulus research project was carried out at the Fraunhofer Institute for Structural Durability and System Reliability...
Prediction of high-impact research: a historical review and research opportunities
Prediction of high-impact research: a historical review and research opportunities
While citation counting has long been the standard for retrospectively operationalizing and assessing high-impact research...
Global research trends and emerging frontiers of nanozymes in cancer therapy based on bibliometric and knowledge mapping analysis from 2001 to 2025
Global research trends and emerging frontiers of nanozymes in cancer therapy based on bibliometric and knowledge mapping analysis from 2001 to 2025
Cancer remains one of the leading causes of mortality worldwide, posing major clinical and societal challenges because of ...
Peptides from de novo Design: Functional, Structural and Biotechnological Details
We are pleased to invite you to participate in a Discovery Molecules Collection entitled "Peptides from de novo desig...
Advances in Digital Chemical Discovery
Advances in Digital Chemical Discovery is proposed as an open-access collection topic for the journal Discover Chemistry, ...
Breakthroughs in Research on the Design of New Materials and Advancements in Thin-Film Solar Cells
As the economy grows rapidly, energy demand increases. The main types of energy used are non-renewable, notably fossil fue...
Protopanaxatriol ameliorates diabetic retinopathy by regulating mTOR/G6PD mediated pentose phosphate pathway
Protopanaxatriol ameliorates diabetic retinopathy by regulating mTOR/G6PD mediated pentose phosphate pathway
In traditional Chinese medicine (TCM), Panax notoginseng and Panax notoginseng saponins (PNS) have been widely used to tre...
Jasminumosides F–K, oligomeric secoiridoid glycosides from jasmin: the flowers of (L.) Aiton
Jasminumosides F–K, oligomeric secoiridoid glycosides from jasmin: the flowers of (L.) Aiton
Six new oligomeric secoiridoid glycosides, namely jasminumosides F–K (1–6), were isolated from the methanolic ...
Meroterpenoids from the fruiting body of with inhibitory activities against budded-to-hyphal-form transition and biofilm formation
Meroterpenoids from the fruiting body of with inhibitory activities against budded-to-hyphal-form transition and biofilm formation
Six novel meroterpenoids, dispanoic acids A–C (1–3), 2′-hydroxydaurichromanic acid (4), albatrellutin A ...
Isoliquiritigenin combined with gemcitabine inhibited lung cancer by suppressing JAK2/STAT3 signaling via lncRNA-p21/miRNA-4534 axis
Isoliquiritigenin combined with gemcitabine inhibited lung cancer by suppressing JAK2/STAT3 signaling via lncRNA-p21/miRNA-4534 axis
Isoliquiritigenin (2’-4’-4-trihydroxychalcone, ISL), a flavonoid from the herbal medicine Glycyrrhiza uralensi...
Antioxidative Japanese herbal medicine formula prevents diabetic renal complications
Antioxidative Japanese herbal medicine formula prevents diabetic renal complications
Diabetes is the leading cause of chronic kidney disease. Hyperglycaemia in diabetes promotes the generation of reactive ox...
A plant alkaloid lycorine inhibits non-small cell lung cancer cell proliferation, metastasis, glycolysis and promotes ferroptosis through the ZNF143/SPC25 axis
A plant alkaloid lycorine inhibits non-small cell lung cancer cell proliferation, metastasis, glycolysis and promotes ferroptosis through the ZNF143/SPC25 axis
Lycorine has been shown to have anti-tumor activity in many cancers, including non-small cell lung cancer (NSCLC). However...
Betulinic acid increases brain-derived neurotrophic factor expression via the PKA, NMDA receptor, and calcineurin pathways in cultured cortical neurons
Betulinic acid increases brain-derived neurotrophic factor expression via the PKA, NMDA receptor, and calcineurin pathways in cultured cortical neurons
Brain-derived neurotrophic factor (BDNF) is a crucial neurotrophin that plays a vital role in neuronal survival, synaptic ...
Chemistry and bioactivities of erinacines from fungi
Chemistry and bioactivities of erinacines from fungi
Erinacines are a class of cyathane diterpenoids predominantly biosynthesized in the mycelia of the medicinal mushroom Heri...
Olive () phenolics for the control of psoriasis via targeting SMYD2 and IL-17A protein–protein interaction networks
Olive () phenolics for the control of psoriasis via targeting SMYD2 and IL-17A protein–protein interaction networks
Psoriasis is a chronic immune-mediated skin disease characterized by keratinocyte hyperproliferation and persistent inflam...
New meroterpenoids from as inhibitors of amyloid β aggregation
New meroterpenoids from as inhibitors of amyloid β aggregation
Three new meroterpenoids, macrocarquinoids J(1)–L(3) were isolated from brown alga, Sargassum macrocarpum, along wit...
Inhibitory effects of three genuine resin glycosides from on porcine lipase assay and docking simulation analysis
Inhibitory effects of three genuine resin glycosides from on porcine lipase assay and docking simulation analysis
Resin glycosides are characteristically present in Convolvulaceae plants. We recently demonstrated that three genuine resi...
Suppression LIF with 8-Gingerol blockades colorectal cancer tumorigenesis by reversing M2-type macrophage polarization
Suppression LIF with 8-Gingerol blockades colorectal cancer tumorigenesis by reversing M2-type macrophage polarization
Colorectal cancer (CRC) remains a formidable therapeutic challenge, with persistent difficulties in developing therapies t...
Neoflavonoids and a megastigmane glycoside from : structural elucidation and biological evaluation
Neoflavonoids and a megastigmane glycoside from : structural elucidation and biological evaluation
A phytochemical investigation of the twigs and stems of Dalbergia cultrata yielded fourteen secondary metabolites, includi...
Effects of extraction methods on the phase, composition, bacteriostatic effect of - decoction
Effects of extraction methods on the phase, composition, bacteriostatic effect of - decoction
The traditional co-decoction method of Radix Scutellariae-Rhizoma Coptidis generates amounts of supramoleculars and aggreg...
Biological activity of isomalabaricane compounds from the marine sponge
Biological activity of isomalabaricane compounds from the marine sponge
This study aimed to investigate the cytotoxic effects of isomalabaricane stellettins Q-V and globostelletins K-N, recently...
The mechanism of the water layer extract of water extract in the treatment of Hepatic fibrosis was investigated using HPLC-MS/MS and network pharmacology
The mechanism of the water layer extract of water extract in the treatment of Hepatic fibrosis was investigated using HPLC-MS/MS and network pharmacology
Hepatic fibrosis (HF) represents a critical stage in the progression of chronic liver disease, for which effective treatme...
A novel mechanism for treating acute lung injury with ligustilide: elucidation via network pharmacology and in vitro validation
A novel mechanism for treating acute lung injury with ligustilide: elucidation via network pharmacology and in vitro validation
Ligustilide inhibits the release of multiple inflammatory factors and alleviates acute lung injury (ALI), although its und...
Anti-asthmatic effects and ingredient annotation of the active fraction from
Anti-asthmatic effects and ingredient annotation of the active fraction from
This research aims to screen the active fraction and explore the action mechanism of Ganoderma lucidum to combat asthma us...
Recent advances in progress of natural anticoagulant active substances
Recent advances in progress of natural anticoagulant active substances
Thrombotic diseases pose a serious threat to human life and health. Anticoagulant drugs are used to treat and prevent thro...
Integrated network pharmacology and pharmacological evaluation to elucidate the effect and mechanism of the novel combination PMS in treatment of osteoporosis
Integrated network pharmacology and pharmacological evaluation to elucidate the effect and mechanism of the novel combination PMS in treatment of osteoporosis
Psoralen, magnoflorine and sweroside were main active components of Xian-Ling-Gu-Bao capsule. PMS (a combination of psoral...
Dual-action mitochondria-targeted prodrugs that both deplete mitochondrial glutathione and deliver a toxic payload to the matrix
Mitochondrial glutathione (mGSH) protects the organelle and the cell against reactive oxygen species (ROS), electrophilic ...
Load More
format_indent_increase