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Clinical and Immunohistochemical Determinants of Hepatocellular Carcinoma in Archival Liver Biopsies in Meru, Kenya
Clinical and Immunohistochemical Determinants of Hepatocellular Carcinoma in Archival Liver Biopsies in Meru, Kenya
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...
Morphological set enrichment enables interpretable prognostication and molecular profiling of meningiomas
Morphological set enrichment enables interpretable prognostication and molecular profiling of meningiomas
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...
Large-Language Models for data extraction from written kidney biopsy reports
Large-Language Models for data extraction from written kidney biopsy reports
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...
Applying AI models to digital placental photographs to automate and improve morphology assessments
Applying AI models to digital placental photographs to automate and improve morphology assessments
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...
Robust Immunohistochemical Detection of α-Synuclein, Tau, and β-amyloid in Human Brain Tissue Archived for up to 78 Years
Robust Immunohistochemical Detection of α-Synuclein, Tau, and β-amyloid in Human Brain Tissue Archived for up to 78 Years
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...
Identifying Single-Nucleotide Polymorphisms Intersecting Alzheimer Disease Pathology and End-of-Life Traits Using Genomic Informational Field Theory (GIFT)
Identifying Single-Nucleotide Polymorphisms Intersecting Alzheimer Disease Pathology and End-of-Life Traits Using Genomic Informational Field Theory (GIFT)
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...
Deep Learning-based Differentiation of Drug-induced Liver Injury and Autoimmune Hepatitis: A Pathological and Computational Approach
Deep Learning-based Differentiation of Drug-induced Liver Injury and Autoimmune Hepatitis: A Pathological and Computational Approach
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...
The Spatial Immune Landscape of Mismatch Repair Deficient Endometrial Cancer: Implications for Clinical Outcomes
The Spatial Immune Landscape of Mismatch Repair Deficient Endometrial Cancer: Implications for Clinical Outcomes
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...
MOSAIC: Explainable AI for Reproducible Histologic Grading and Prognostic Stratification in Breast Cancer
MOSAIC: Explainable AI for Reproducible Histologic Grading and Prognostic Stratification in Breast Cancer
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...
Pre-analytical delay of blood cultures: poor compliance with the recommended standard is linked to laboratory centralisation.
Pre-analytical delay of blood cultures: poor compliance with the recommended standard is linked to laboratory centralisation.
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...
Cancer Stem Cell-Associated Marker Expression in Chemotherapy-Treated Wilms Tumour
Cancer Stem Cell-Associated Marker Expression in Chemotherapy-Treated Wilms Tumour
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...
Shifts in the pathogen spectrum and epidemiology of respiratory tract infections in the post-COVID-19 era: A study from Quzhou, Eastern China
Shifts in the pathogen spectrum and epidemiology of respiratory tract infections in the post-COVID-19 era: A study from Quzhou, Eastern China
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...
Artificial Intelligence Devices for Image Analysis in Digital Pathology
Artificial Intelligence Devices for Image Analysis in Digital Pathology
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...
Quantitative assessment of collagen architecture from routine histopathological images shows concordance with Second Harmonic Generation microscopy
Quantitative assessment of collagen architecture from routine histopathological images shows concordance with Second Harmonic Generation microscopy
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...
Algorithm-Based Model for Gastrointestinal and Liver Histopathological Analysis Using VGG16 and Specialized Stains: Statistical Validation of Thresholds in AI-Driven Digital Pathology
Algorithm-Based Model for Gastrointestinal and Liver Histopathological Analysis Using VGG16 and Specialized Stains: Statistical Validation of Thresholds in AI-Driven Digital Pathology
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...
GPR143, a novel immunohistochemical marker for renal tumors with FLCN/TSC/MTOR-TFE alterations
GPR143, a novel immunohistochemical marker for renal tumors with FLCN/TSC/MTOR-TFE alterations
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...
Data Matters: The Impact of Data Curation in the Classification of Histopathological Datasets
Data Matters: The Impact of Data Curation in the Classification of Histopathological Datasets
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...
Sex moderates apolipoprotein E ε4 effects on sleep expression and memory retention
Sex moderates apolipoprotein E ε4 effects on sleep expression and memory retention
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...
Nanopore Whole-Genome Sequencing for Rapid, Comprehensive Molecular Diagnostics of Brain Tumors in Adult Patients
Nanopore Whole-Genome Sequencing for Rapid, Comprehensive Molecular Diagnostics of Brain Tumors in Adult Patients
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...
Leveraging Open-Source Solutions to Build a Low-Cost Digital Pathology Pipeline for Translational Research
Leveraging Open-Source Solutions to Build a Low-Cost Digital Pathology Pipeline for Translational Research
medRxiv - the preprint server for biology, operated by openRxiv, a nonprofit organization dedicated to advancing scientifi...
Hippo signalling pathway mediates oncogenic properties of NAB2::STAT6 in solitary fibrous tumour
Hippo signalling pathway mediates oncogenic properties of NAB2::STAT6 in solitary fibrous tumour
Solitary fibrous tumour (SFT) is a rare mesenchymal neoplasm molecularly defined by the NAB2::STAT6 gene fusion (GF), an a...
Pan-cancer analysis of cholesterol metabolism reveals the uptake as a modulator of tumor immune features and of the KRAS pathway
Pan-cancer analysis of cholesterol metabolism reveals the uptake as a modulator of tumor immune features and of the KRAS pathway
Cholesterol dysregulation plays a central role in tumor progression and has emerged as a potential therapeutic target. Its...
Disconnect between in vitro and in vivo efficacy of the MPS1 inhibitor NTRC 0066-0 against glioblastoma
Disconnect between in vitro and in vivo efficacy of the MPS1 inhibitor NTRC 0066-0 against glioblastoma
Glioblastoma (GBM) is the most common adult primary brain tumor for which new therapeutic strategies are desperately neede...
Single-cell mapping of cholesterol metabolism reveals FDPS as a therapeutic vulnerability in hepatocellular carcinoma
Single-cell mapping of cholesterol metabolism reveals FDPS as a therapeutic vulnerability in hepatocellular carcinoma
Dysregulated cholesterol metabolism has emerged as a crucial driver of hepatocellular carcinoma (HCC) progression and immu...
Discover personalized drug opportunity and optimized tumor-infiltrating lymphocyte therapy for rare cancer: an organoid-based whole-journey clinical mapping study in a neuroendocrine cancer patient
Discover personalized drug opportunity and optimized tumor-infiltrating lymphocyte therapy for rare cancer: an organoid-based whole-journey clinical mapping study in a neuroendocrine cancer patient
Rare cancer patients face dire prognoses due to high malignancy and scarce treatment options, underscoring an imperative f...
Peripheral blood immune cell subsets as non-invasive biomarkers of colorectal cancer stage, laterality, metastasis and survival
Peripheral blood immune cell subsets as non-invasive biomarkers of colorectal cancer stage, laterality, metastasis and survival
Colorectal cancer (CRC) is a heterogeneous disease in which immune dynamics critically influence tumour progression and pa...
Strategies to target PD-1/PD-L1 in the tumor microenvironment
Strategies to target PD-1/PD-L1 in the tumor microenvironment
In recent years, cancer immunotherapy has become one of the most important methods in cancer treatment, which can kill tum...
Hepatocellular carcinoma and vitamin D metabolism: novel targets and therapeutic strategies
Hepatocellular carcinoma and vitamin D metabolism: novel targets and therapeutic strategies
Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related death worldwide. While age-standardized incidence...
Distinct clinical and genomic profiles of braf mutation subtypes in Chinese colorectal cancer: a retrospective cohort study with cross-population validation
Distinct clinical and genomic profiles of braf mutation subtypes in Chinese colorectal cancer: a retrospective cohort study with cross-population validation
To characterize the clinicogenomic features, prognostic significance and therapeutic implications of BRAF mutation subtype...
B3GNT3 facilitates NFKB2 processing and non-canonical NF-κB activation to drive lung adenocarcinoma progression
B3GNT3 facilitates NFKB2 processing and non-canonical NF-κB activation to drive lung adenocarcinoma progression
Aberrant glycosylation is implicated in tumor progression. However, the role of β-1,3-N-acetylglucosaminyltransferase...
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