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How ligands tune the parathyroid hormone receptor’s grip on β-arrestin

β-arrestins are known modulators of GPCR signaling, but their precise interaction with class B GPCRs is poorly unders...

Nature Structural & Molecular Biology

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Rap1-mediated steric hindrance protects telomeres from MRX sensing

Telomere capping largely depends on telomere length. Abnormally short telomeres are prone to activate DNA damage checkpoin...

Nature Structural & Molecular Biology

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Author Correction: Structure, assembly and inhibition of the Toxoplasma gondii respiratory chain supercomplex

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...

Nature Structural & Molecular Biology

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Soma-to-germline miRNA inheritance through yolk promotes stress resilience in progeny

At the onset of reproduction, oviparous animals synthesize large amounts of yolk in somatic tissues to provide lipids and ...

Nature Structural & Molecular Biology

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Dynamic regulation of H3K9 dimethylation drives mouse minor zygotic genome activation

Minor zygotic genome activation (ZGA) is crucial for early development and totipotency acquisition; however, the regulator...

Nature Structural & Molecular Biology

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Yolk transports miRNAs to embryos and enhances progeny stress resilience

This study shows that yolk, a conserved vehicle for nutrient provisioning to developing eggs, also transports regulatory s...

Nature Structural & Molecular Biology

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Distinct repair outcomes from single and convergent replication fork collapse

Replication fork collapse at single-strand DNA breaks threatens genome stability but how such forks are repaired and resol...

Nature Structural & Molecular Biology

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How cohesin guides DNA repair via scanning and tethering

A broken chromosome must find an identical DNA sequence among billions of bases packed into the nucleus. Although homologo...

Nature Structural & Molecular Biology

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Sex differences in coordination of center of mass kinematics during table tennis footwork

Journal Of Biomechanics

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The effect of interposition arthroplasty on the contact mechanics of the elbow joint

Journal Of Biomechanics

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From classical models to attention-based transformers: A comparative study of injury prediction pipelines in female varsity soccer

Journal Of Biomechanics

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Animal ex-vivo model for the reproduction of the human ascending aorta

Journal Of Biomechanics

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An In-Vitro simulator for investigating flow disturbances in the left ventricle during controlled external impact

Journal Of Biomechanics

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Simulation-based analysis of rigid alignment bias in PCA of weight-bearing foot shapes

Journal Of Biomechanics

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Large-scale study of the hip, knee, and ankle reveals sex and angle-dependent muscle volume and torque scaling relationships

Journal Of Biomechanics

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Influence of noise and effect characteristics on statistical power in the analyses of one-dimensional biomechanical trajectories

Journal Of Biomechanics

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Age-dependent mechanical heterogeneity in immature murine bone: A nanoindentation mapping study

Journal Of Biomechanics

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Screw-bone interface loads from rod bending: Development of an instrumented spinal fusion simulator

Journal Of Biomechanics

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Assessing isometric ankle abductor strength with a novel device: Reliability and electromyographic validation

Journal Of Biomechanics

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Posterior marker set for shoulder kinematic analysis using optoelectronic systems

Journal Of Biomechanics

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Analysis of head movements during gait in healthy populations and people with neurological disorders: a systematic review

Journal Of Biomechanics

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Datasets for acquiring 3D bone shapes: a systematic review

Journal Of Biomechanics

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Design of epicardial restraints for optimized passive filling of the right ventricle

Journal Of Biomechanics

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Concurrent validity of Theia3D markerless compared to marker-based motion capture for movement synergy analysis during the 1-minute sit-to-stand test

Journal Of Biomechanics

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Hamstrings muscle dynamics during the Nordic hamstring exercise and high-speed running

Journal Of Biomechanics

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Altered energy dissipation patterns and increased ground reaction force in patients with chronic ankle instability after fatiguing exercises

Journal Of Biomechanics

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Synergistic patterns during steady-state wheelchair propulsion in male wheelchair rugby players with cervical spinal cord injury: influence of functional classification and competitive level

Journal Of Biomechanics

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Automated dual-stream deep network design for activity recognition

Journal Of Biomechanics

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Doxorubicin-Induced Cardiotoxicity: Molecular Mechanisms to Novel Therapeutic Frontiers of Recent Preclinical Discoveries

Cardiotoxicity is the most common side effect of various chemotherapy medications. Doxorubicin (DOX), which belongs to the...

Cell Biochemistry And Biophysics

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Extracellular levels of glutamate, glutamine, cystine, glutathione, and xanthine correlate with transporter expression in tamoxifen - resistant MCF-7 cells and poor overall survival in breast cancer patients

Tamoxifen resistance development in breast cancer cells is a major clinical challenge. Metabolic alterations play a fundam...

Cell Biochemistry And Biophysics

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