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Synergistic control of human arm movement. A systematic review and perspective
Synergistic control of human arm movement. A systematic review and perspective
In recent years, the hypothesis of synergistic control of movements has gained popularity. According to this hypothesis, m...
Neuroprotective effects of against aluminium chloride-Induced neurotoxicity in rats: insights into oxidative and cholinergic alterations
Neuroprotective effects of against aluminium chloride-Induced neurotoxicity in rats: insights into oxidative and cholinergic alterations
Oxidative imbalance and cholinergic dysfunction are key contributors to neurodegeneration. Aluminium chloride (AlCl3) is a...
Changes in the mechanics of rat calf muscle contraction during the first five weeks after foot amputation
Changes in the mechanics of rat calf muscle contraction during the first five weeks after foot amputation
This study analyzes changes in the contractile properties of rat calf muscle during the first five weeks after foot amputa...
Optimizing diazepam dosing to reduce mortality in the lithium-pilocarpine model of epilepsy in rats: a methodological study
Optimizing diazepam dosing to reduce mortality in the lithium-pilocarpine model of epilepsy in rats: a methodological study
The lithium-pilocarpine model is widely used to study temporal lobe epilepsy (TLE), but its utility is limited by high and...
Fisetin as a neuroprotective agent: Docking-based modulation of dopaminergic and inflammatory pathways in Parkinson’s disease
Fisetin as a neuroprotective agent: Docking-based modulation of dopaminergic and inflammatory pathways in Parkinson’s disease
Parkinson’s disease is an progressive neurodegenerative condition whose pathology manifests as the selective destruc...
Resveratrol exacerbates spike-wave discharges in genetic absence epileptic WAG/Rij rats
Resveratrol exacerbates spike-wave discharges in genetic absence epileptic WAG/Rij rats
Resveratrol (RES), a natural supplement with reported antiepileptic effects, has not been evaluated in absence ep...
Mitochondrial dynamics and neuronal death in neurodegenerative diseases
Mitochondrial dynamics and neuronal death in neurodegenerative diseases
Neurodegenerative diseases like Parkinson’s, Alzheimer’s, amyotrophic lateral sclerosis, and Huntington’...
Desynchronization of neural networks induced by transcranial magneto-acoustical stimulation: a modeling study
Desynchronization of neural networks induced by transcranial magneto-acoustical stimulation: a modeling study
Transcranial magneto-acoustical stimulation (TMAS) is a promising non-invasive brain stimulation technique that c...
Phytochemical profiling and preliminary assessment of the antiepileptic activity of Bauhinia variegata leaves
Phytochemical profiling and preliminary assessment of the antiepileptic activity of Bauhinia variegata leaves
Plant-based therapeutics are increasingly studied as alternatives or add-ons to conventional antiepileptic medications. Ba...
Administration of decreases the mortality caused by audiogenic seizures in DBA/1 mice
Administration of decreases the mortality caused by audiogenic seizures in DBA/1 mice
The research intended to probe the impact of probiotics (Pb) on seizure-induced respiratory arrest (S-IRA), gut flora, and...
Immunomodulatory effects of anesthetic drugs and their implications in neurodegenerative disease progression
Immunomodulatory effects of anesthetic drugs and their implications in neurodegenerative disease progression
Anesthetic drugs are known to exert immunomodulatory effects, which may influence the progression of neurodegenerative dis...
Effects of atropine on the electrophysiological properties of LCC-channels of the nuclear membrane of Purkinje neurons
Effects of atropine on the electrophysiological properties of LCC-channels of the nuclear membrane of Purkinje neurons
Ca2+ signaling remains essential for excitatory cells’ functioning, but it is still unknown what channels are respon...
Heterogeneous typing of physical-mental symptoms in stroke patients during recovery phase based on latent class analysis and influencing factors
Heterogeneous typing of physical-mental symptoms in stroke patients during recovery phase based on latent class analysis and influencing factors
To explore the heterogeneous typing characteristics of physical-mental symptoms in stroke patients during the recovery pha...
Huntington’s disease: neurophysiological insights into molecular mechanisms, disease models, and therapeutic strategies
Huntington’s disease: neurophysiological insights into molecular mechanisms, disease models, and therapeutic strategies
Huntington’s disease (HD) is a progressive inherited neurodegenerative disorder characterized by motor, cog...
Role of TFEB in parkinson’s disease: pathophysiological insights and therapeutic approaches
Role of TFEB in parkinson’s disease: pathophysiological insights and therapeutic approaches
Parkinson’s disease (PD) is a progressive neurological disorder characterized by stiffness, tremors, and wa...
EEG insights from Ukrainian civilians: cohort differences before and during war
EEG insights from Ukrainian civilians: cohort differences before and during war
This study examined electrophysiological patterns in Ukrainian civilians by comparing EEG recordings obtained before (2010...
A recent update on involvement of gut microbiota alterations in alzheimer’s disease pathogenesis
A recent update on involvement of gut microbiota alterations in alzheimer’s disease pathogenesis
Changes in gut microbiota (GMB) composition, referred to as dysbiosis, are progressively associated with the onset and adv...
Unlocking the P2X7 Pathway: A Therapeutic Target in Alzheimer’s Disease
Unlocking the P2X7 Pathway: A Therapeutic Target in Alzheimer’s Disease
Alzheimer’s disease (AD) is a gradually worsening neurodegenerative disorder marked by memory impairment, p...
Variations in gait patterns in women and men with Parkinson’s disease
Variations in gait patterns in women and men with Parkinson’s disease
Parkinson’s disease is a progressive brain disorder affecting males 1.5 times more than females. T...
Identifying risk factors and developing predictive models for cognitive impairment in cerebral small vessel disease
Identifying risk factors and developing predictive models for cognitive impairment in cerebral small vessel disease
Cognitive impairment is a frequent and disabling complication of cerebral small vessel disease (CSVD). This study...
Hypoxia Modulates Membrane Mechanics in Pancreatic Cancer
Hypoxia Modulates Membrane Mechanics in Pancreatic Cancer
Aggressive cancer cells such as pancreatic cells exhibit an enhanced metastatic phenotype that involves cell migration and...
Design of a Multi-Epitope Vaccine using β-barrel Outer Membrane Proteins Identified in
Design of a Multi-Epitope Vaccine using β-barrel Outer Membrane Proteins Identified in
Chlamydia trachomatis is an obligate intracellular Gram-negative pathogen that causes sexually transmitted infections (STI...
Yeast Membrane Hydration is Maintained Under Ethanol Exposure
Yeast Membrane Hydration is Maintained Under Ethanol Exposure
Yeasts are able to tolerate different environmental conditions, including stress situations. Given their broad application...
Bilayer-Dependent Recognition of Docosahexaenoic Acid by the Transmembrane Domain of FATP3
Bilayer-Dependent Recognition of Docosahexaenoic Acid by the Transmembrane Domain of FATP3
Fatty acid Transport Protein 3 (FATP3) is a single-pass transmembrane protein implicated in the uptake and intracellular t...
Celebrating 50 Years of Single-Channel Recording with the Patch Clamp
Celebrating 50 Years of Single-Channel Recording with the Patch Clamp
Fifty years ago, Erwin Neher and Bert Sakmann published a Nature paper on their recording of discrete, step-like currents ...
Predicting Toxicity of Insect Venom-Derived Antimicrobial Peptides Using MD Simulations: A Comparative Study of Multi-Component and Realistic Mammalian Membrane Models
Predicting Toxicity of Insect Venom-Derived Antimicrobial Peptides Using MD Simulations: A Comparative Study of Multi-Component and Realistic Mammalian Membrane Models
Insect venom-derived antimicrobial peptides (AMPs) hold significant therapeutic promise, but their application is constrai...
Integrative Multiscale Simulations Uncover the Mechanistic Principles Governing COPII Mediated Vesicle Formation
Integrative Multiscale Simulations Uncover the Mechanistic Principles Governing COPII Mediated Vesicle Formation
Arkhipov A, Yin Y, Schulten K (2008) Four-scale description of membrane sculpting by BAR domains. Biophys J 95:2806–2821Ar...
Peptide-Assisted Membrane Permeabilization: Effects of Waveform Polarity, Inter-Monopulse Interval, and Surface Charge in Red Blood Cells and Planar Lipid Bilayers
Peptide-Assisted Membrane Permeabilization: Effects of Waveform Polarity, Inter-Monopulse Interval, and Surface Charge in Red Blood Cells and Planar Lipid Bilayers
Permeabilization of biomembranes by polycationic peptides is known to depend on the membrane potential, although the exact...
Na Uptake Triggered in Adrenal Chromaffin Cells by a 5-ns Electric Pulse is Facilitated by Ca Influx Via an L-Type-Like Ca Channel Independent of Changes in Membrane Potential
Na Uptake Triggered in Adrenal Chromaffin Cells by a 5-ns Electric Pulse is Facilitated by Ca Influx Via an L-Type-Like Ca Channel Independent of Changes in Membrane Potential
Whole-cell voltage patch clamp studies have shown that in bovine adrenal chromaffin cells held at -70 mV, a single 5-ns, 5...
Targeting ORAI1-Mediated Calcium Influx in Triple-Negative Breast Cancer: A Computational Drug Discovery Approach
Targeting ORAI1-Mediated Calcium Influx in Triple-Negative Breast Cancer: A Computational Drug Discovery Approach
Store-operated calcium entry (SOCE) is a crucial pathway that aids in restoring depleted calcium levels in the endoplasmic...
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