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Self-defenestration associated with 3-MeO-PCE ingestion
Self-defenestration associated with 3-MeO-PCE ingestion
New psychoactive substances (NPS) continue to proliferate worldwide, and the pharmacological and toxicological profiles of...
Classification of acceleration and deceleration craniocerebral injuries by using cascaded deep learning models
Classification of acceleration and deceleration craniocerebral injuries by using cascaded deep learning models
Accurately determining the manner of craniocerebral injuries is critical in forensic practice, especially when distinguish...
T1-Weighted MRI of the proximal humerus: Toward a non-ionizing approach to forensic age estimation in a French cohort
T1-Weighted MRI of the proximal humerus: Toward a non-ionizing approach to forensic age estimation in a French cohort
Forensic age estimation of living individuals is increasingly performed using magnetic resonance imaging (MRI) to avoid io...
Age and sex estimation from Japanese femoral computed tomographic images using foundation models
Age and sex estimation from Japanese femoral computed tomographic images using foundation models
This study evaluated the feasibility and performance of a deep learning–based multitask framework for estimating sex...
An avuncular relationship generating a parent–offspring signal in forensic familial DNA searching: a case report
An avuncular relationship generating a parent–offspring signal in forensic familial DNA searching: a case report
In 2019, a series of vehicle burglaries occurred near the Dead Sea, Israel. DNA profiles obtained from six crime scenes we...
Mapping two decades of forensic virtopsy: a comprehensive bibliometric analysis (2006–2025)
Mapping two decades of forensic virtopsy: a comprehensive bibliometric analysis (2006–2025)
This study presents a comprehensive bibliometric analysis of the forensic post-mortem forensic imaging research domain, ex...
Pre-ejaculate – an overlooked body fluid with high amounts of DNA
Pre-ejaculate – an overlooked body fluid with high amounts of DNA
Pre-ejaculate is a clear, sperm-free liquid secreted by the male bulbourethral glands. Since it is currently not a subject...
Sex estimation from the mandible in 3D computed tomography images
Sex estimation from the mandible in 3D computed tomography images
This study aimed to reveal sex-related variable characteristics through morphometric measurements on the mandible and to p...
Fentanyl in forensic autopsies: Trends, circumstances, and toxicological findings
Fentanyl in forensic autopsies: Trends, circumstances, and toxicological findings
Postmortem fentanyl detection in medicolegal autopsy cases presents a fundamental interpretive challenge: detection does n...
From biochemical markers to machine learning: a review of postmortem interval estimation via vitreous humor analysis
From biochemical markers to machine learning: a review of postmortem interval estimation via vitreous humor analysis
Accurate estimation of the postmortem interval (PMI) is pivotal in forensic investigations and medicolegal proceedings. Ho...
Comparative study of STR, SNP, and mtDNA recovery in teeth after thermal exposure
Comparative study of STR, SNP, and mtDNA recovery in teeth after thermal exposure
High-temperature exposure of biological samples at fire scenes induces significant DNA degradation, thereby complicating a...
Radiopaque ring sign as a distinct finding at the entry site of gunshot wounds on postmortem CT
Radiopaque ring sign as a distinct finding at the entry site of gunshot wounds on postmortem CT
Postmortem computed tomography (PMCT) is widely used in the evaluation of gunshot wounds, particularly for the assessment ...
β-Catenin stabilization protects against alveolar hemorrhage through amphiregulin- and BATF-mediated Tregs
β-Catenin stabilization alters the CD8+ T cell phenotype. β-Catenin is required for both αβ and γδ T cell development (21...
Cardiac conduction system malformations in heterotaxy result from dysregulated Pitx2 expression
Disposition of CCS in Cryptic–/– embryos at E18.5. To investigate CCS disposition in mouse heterotaxy, we first examined ...
Targeting PI3Kγ anchoring enhances CFTR membrane localization and modulator efficacy via PKD1
Research ArticleCell biologyPulmonology Open Access | 10.1172/jci.insight.198846 Alessandra M...
Ex vivo–expanded allogeneic Vδ2 T cells specifically reduce reservoirs of HIV-1 following latency reversal
Sex as a biological variable. Self-reported biological sex of study participants was included as a variable for the analy...
CD9 regulates macrophage-mediated remodeling of adipose tissue in obesity
Research ArticleImmunologyMetabolism Open Access | 10.1172/jci.insight.193837 Julia Chini,1,2...
Reduced late endosome/lysosome function promotes SLE through chronic PI3K activity and SHP-1/SHIP-1 defects
Multiple hematopoietic cell types exhibit LEL dysfunction. Previous studies showed that bone marrow–derived Mφs (BMMφs) f...
Hypothyroidism impairs skeletal muscle regeneration after injury by altering myogenic and nonmyogenic pathways
Skeletal muscle regeneration after injury is impaired during hypothyroidism. To assess the impact of thyroid hormone defi...
Extracellular vesicle miR-93-5p cargo regulates glomerular endothelial cell damage in Alport syndrome
Research ArticleCell biologyNephrology Open Access | 10.1172/jci.insight.197643 Charmi Dedhia...
Endothelial oncogenic KRAS mutation drives the dynamics of microglia and macrophages in brain arteriovenous malformation
ECs carrying mutant KRAS lead to bAVM genesis. We previously showed that ECs carrying mutant human KRAS (KRAS-ECs) are su...