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Periostin in joint physiology and pathology: multiple roles from mechanisms to clinical perspectives
Periostin in joint physiology and pathology: multiple roles from mechanisms to clinical perspectives
Joint-related diseases, including osteoarthritis (OA), rheumatoid arthritis (RA), intervertebral disc degeneration (IDD), ...
ER stress affects proliferation and induces polyploidization of cultured human HaCaT and A431 cells
ER stress affects proliferation and induces polyploidization of cultured human HaCaT and A431 cells
Endoplasmic reticulum (ER) stress is the accumulation of misfolded or defective proteins in the ER. ER stress is capable o...
Fiber type-specific expression of LACTB leverages a function in oxidative metabolism
Fiber type-specific expression of LACTB leverages a function in oxidative metabolism
Skeletal muscle is composed of type I and type II fibers, each characterized by specific metabolic machinery. LACTB is a c...
Functional suppression accompanies internal mitochondrial reorganization during cellular reprogramming
Functional suppression accompanies internal mitochondrial reorganization during cellular reprogramming
During the conversion of fibroblasts into induced pluripotent stem cells (iPSCs), cellular metabolism shifts from oxidativ...
Oncogenic overexpression of kallikrein-related peptidase 7 is associated with the progression of thyroid cancer
Oncogenic overexpression of kallikrein-related peptidase 7 is associated with the progression of thyroid cancer
Mounting evidence suggests that the kallikrein-related peptidase family is dysregulated in thyroid cancer. However, previo...
Localization of dendritic cells and T cells within the tumor microenvironment in different types of skin cancer
Localization of dendritic cells and T cells within the tumor microenvironment in different types of skin cancer
Immunophenotyping of tumor-infiltrating immune cells is increasingly important for understanding the tumor microenvironmen...
SASP-driven vascular aging: unraveling the transcriptional nexus in endothelial senescence and cardiovascular disease
SASP-driven vascular aging: unraveling the transcriptional nexus in endothelial senescence and cardiovascular disease
Endothelial cell senescence represents a critical mechanistic driver in the initiation and progression of cardiovascular d...
Effects of obesity on DNA methylation and DNA methyltransferases in the reproductive system
Effects of obesity on DNA methylation and DNA methyltransferases in the reproductive system
Obesity is increasingly recognized as a condition with profound systemic and epigenetic consequences. However, the molecul...
Approaches to visualize, quantify, and manipulate phosphoinositides in cells
Approaches to visualize, quantify, and manipulate phosphoinositides in cells
Phosphoinositides are low-abundance regulatory lipids that control a broad range of cellular processes, from membrane traf...
Methodological framework for chromogenic mRNA detection using in situ hybridization chain reaction
Methodological framework for chromogenic mRNA detection using in situ hybridization chain reaction
In situ hybridization chain reaction (HCR) is a highly sensitive method for visualizing single-molecule messenger RNA (mRN...
The peroxisomal importomer can accommodate an intrinsically disordered protein of 1247 residues
The peroxisomal importomer can accommodate an intrinsically disordered protein of 1247 residues
Peroxisomal matrix proteins are nuclear encoded and synthesized in the cytosol. It is well established that folded, cofact...
Artificial intelligence in small tissue biopsies: diagnostic applications, histochemical integration, and methodological challenges in surgical pathology
Artificial intelligence in small tissue biopsies: diagnostic applications, histochemical integration, and methodological challenges in surgical pathology
Small tissue biopsies, including renal core biopsies, bone marrow trephines, gastrointestinal endoscopic samples, prostate...
Modulation of angiogenic, inflammatory, and matrix remodeling responses in type 2 diabetic wounds by a decellularized dermal scaffold and adjunct biophysical stimulation
Modulation of angiogenic, inflammatory, and matrix remodeling responses in type 2 diabetic wounds by a decellularized dermal scaffold and adjunct biophysical stimulation
Impaired wound healing in type 2 diabetes is largely attributed to dysregulated cellular responses, defective extracellula...
DHX37 protein and mRNA expression patterns in breast and ovarian cancer and their prognostic implications
DHX37 protein and mRNA expression patterns in breast and ovarian cancer and their prognostic implications
DEAH-box RNA helicase 37 (DHX37) is a highly conserved RNA helicase involved in ribosome biogenesis, RNA metabolism and im...
Visualisation of peroxisomes: a journey through seven decades
Visualisation of peroxisomes: a journey through seven decades
Peroxisomes are ubiquitous, oxidative organelles in eukaryotes with conserved functions in cellular lipid metabolism and r...
A rapid and robust translational model for testicular aging research
A rapid and robust translational model for testicular aging research
In humans, testicular peritubular cells (TPCs) form a small compartment surrounding the seminiferous tubules and, as shown...
AGEs derived from high-sugar diets induce functional impairment of odontogenic stem cells via RAGE-mediated endoplasmic reticulum stress
AGEs derived from high-sugar diets induce functional impairment of odontogenic stem cells via RAGE-mediated endoplasmic reticulum stress
This investigation sought to determine whether the formation and progressive buildup of advanced glycation end products (A...
The stem cell potential of bovine milk: a comparative study of colostrum and mature milk
The stem cell potential of bovine milk: a comparative study of colostrum and mature milk
Mesenchymal stem cells (MSCs) are widely utilized in regenerative medicine owing to their differentiation potential and pa...
Epigenetic orchestration by DNMT3B and DNMT3L throughout oocyte maturation
Epigenetic orchestration by DNMT3B and DNMT3L throughout oocyte maturation
DNA methylation represents a fundamental epigenetic mechanism regulating gene expression and developmental processes. In t...
Temporal dynamics of hippocampal morphological changes in cisplatin-induced neurotoxicity and prophylactic and therapeutic effects of pioglitazone
Temporal dynamics of hippocampal morphological changes in cisplatin-induced neurotoxicity and prophylactic and therapeutic effects of pioglitazone
Alhowail, A. H. (2025). Cisplatin induces hippocampal neurotoxicity and cognitive impairment in rats...
Climate change and the psychosomatic health of animals: Mechanisms, manifestations, and mitigation strategies
Climate change and the psychosomatic health of animals: Mechanisms, manifestations, and mitigation strategies
Bagath, M., Krishnan, G., Devaraj, C., Rashamol, V. P., Pragna, P., Lees, A. М., & Sejian, V. (2...
Multitarget approach to babesiosis therapy: An in vitro study of therapeutic compounds
Multitarget approach to babesiosis therapy: An in vitro study of therapeutic compounds
Arbon, D., Mach, J., Čadková, A., Sipkova, A., Stursa, J., Klanicová, K., Machado, M., Ganter, M., L...
Effect of autologous platelet-rich plasma on gastric wall regeneration after experimental gastrotomy in rabbits
Effect of autologous platelet-rich plasma on gastric wall regeneration after experimental gastrotomy in rabbits
Cole, B. J., Seroyer, S. T., Filardo, G., Bajaj, S., & Fortier, L. A. (2010). Platelet-rich plas...
The multifunctional role of vitamin K2 in biological systems
The multifunctional role of vitamin K2 in biological systems
AlBlooshi, S. (2025). Vitamin K and women”s health: A review. Frontiers in Global Women’s Health, 6,...
Interplay between obesity, low-grade inflammation, and hormonal biomarkers: A case-control study
Interplay between obesity, low-grade inflammation, and hormonal biomarkers: A case-control study
de Oliveira dos Santos, A. R., de Oliveira Zanuso, B., Miola, V. F. B., Barbalho, S. M., Santos Buen...
Hypolipidemic activity in a series of new hybrids of orotic acid and 1,2,4-triazole
Hypolipidemic activity in a series of new hybrids of orotic acid and 1,2,4-triazole
Ballantyne, C. M., & Norata, G. D. (2025). The evolving landscape of targets for lipid lowering:...
Biodegradable packaging materials for food products
Biodegradable packaging materials for food products
Abreu, D. A., Losada, P., Maroto, J., Cruz, F., & José, M. (2011). Natural antioxidant active pa...
Relationship between the Bvg+ phenotype of clinical isolates of Bordetella bronchiseptica and their immunogenic potential
Relationship between the Bvg+ phenotype of clinical isolates of Bordetella bronchiseptica and their immunogenic potential
Belhart, K., Sisti, F., Gestal, M. C., & Fernández, J. (2023). Bordetella bronchiseptica diguany...
Effectiveness of ultrasound examination in mono- and mixed infections of dogs
Effectiveness of ultrasound examination in mono- and mixed infections of dogs
Arita, N., Yamane, I., & Takemura, N. (2003). Comparison of canine heartworm removal rates using...
Association of HPV viral load, estrogen receptor α signaling, and inflammatory serum biomarkers with cervical cancer progression
Association of HPV viral load, estrogen receptor α signaling, and inflammatory serum biomarkers with cervical cancer progression
Bahadoran, E., Rahmani, B., Nazari, E., Hosseinnezhad, A., & Samiee Rad, F. (2025). Comparison o...
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