SCI Abstract

search
CRISPR/Cas9 system-mediated p21 knockout impairs the MITF signaling pathway
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
The secretory production of cutinase ICCG-A2 in Corynebacterium glutamicum using acetate as the sole carbon source
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Gene expression in synthetic biology: Going with the light
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
A cell-free platform for the high-efficiency synthesis and screening of PET hydrolase
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Immobilized laccase reactors for process intensification: Kinetic comparison of batch and continuous-flow systems
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Development of a magnetic β-glucosidase biocatalyst: Structural and functional characterization with enhanced thermal stability
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Casein-coated Fe3O4 nanozymes with enhanced peroxidase-like activity for synergistic doxorubicin delivery and catalytic anticancer therapy
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Preparation and characterization polyethylene Glycol @ Alginate-Chitosan nanocomposite tailored for oral insulin delivery
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Epigenetic regulation of transgenes
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
CRISPR Cas9 revolutionizing genetic engineering and therapeutic applications
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Morphological and molecular characterization of Mexican Hericium erinaceus strains
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Insight into the biotransformation pathway of oat phenolic in enzyme hydrolysis coupled with Monascus fermentation
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Metabolic engineering of tomato fruits for production of raspberry ketone glycosides
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Zn fortification and lipids modifications in mustard seeds treating with next gen plasma technology
All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
A PIVOT towards single-cell functional genetic screening in plants
A PIVOT towards single-cell functional genetic screening in plants
We developed PIVOT, a single-cell screening platform for functional characterization of plant genes. PIVOT enables deliver...
Newcomer anti-IL-33 makes strides in COPD
Newcomer anti-IL-33 makes strides in COPD
AstraZeneca’s IL-33 antibody tozorakimab targets two distinct signaling pathways engaged in COPD: inflammation and e...
Circling back to RNA vaccines
While circRNA is often framed as a more stable, longer-lasting alternative to linear mRNA, its real-world advantages remai...
Immune-remodeling mRNAs expressing IRF8 or NIK generate durable antitumor immunity in multiple cancer models
Immune-remodeling mRNAs expressing IRF8 or NIK generate durable antitumor immunity in multiple cancer models
Although immunotherapy has benefited a subset of persons with cancer, its broader efficacy remains limited, primarily beca...
Deep peptide recognition profiling decodes TCR specificity and enables disease-associated antigen discovery
Deep peptide recognition profiling decodes TCR specificity and enables disease-associated antigen discovery
Predicting T cell receptor (TCR) specificity on the basis of sequence is challenging because TCRs of similar sequence can ...
Guide DNA — not RNA — expands the CRISPR toolkit
Guide DNA — not RNA — expands the CRISPR toolkit
Cas12 nucleases can use guide DNA instead of guide RNA, which switches their targets from DNA to RNA.
DNA-guided CRISPR–Cas12 for cellular RNA targeting
DNA-guided CRISPR–Cas12 for cellular RNA targeting
Here, we present ΨDNA, a DNA-based guide that enables RNA targeting by Cas12 nucleases, overcoming the traditional re...
Widespread DNA off-targeting confounds RNA chromatin occupancy studies
Widespread DNA off-targeting confounds RNA chromatin occupancy studies
Several high-throughput sequencing methods have been used to study the genome-wide chromatin occupancy of long noncoding R...
Improving lipid production by  for renewable fuel production based on machine learning
Improving lipid production by for renewable fuel production based on machine learning
Microbial lipid fermentation encompasses intricate complex cell growth processes and heavily relies on expert experience f...