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Moderating Role of State and Trait Positive Affect in Virtual Reality Exposure for Public Speaking Anxiety: Protocol for a Multisite Experimental Study
Moderating Role of State and Trait Positive Affect in Virtual Reality Exposure for Public Speaking Anxiety: Protocol for a Multisite Experimental Study
Background: The identification of moderators of exposure-based cognitive behavior therapy (EXCBT) outcome has the potentia...
Effects of Aerobic Training Versus Behavioral Intervention to Increase Physical Activity for Disease Control in Patients With Asthma: Protocol for a Randomized Trial
Effects of Aerobic Training Versus Behavioral Intervention to Increase Physical Activity for Disease Control in Patients With Asthma: Protocol for a Randomized Trial
Background: Aerobic training (AT) and behavioral intervention (BI) aimed at increasing physical activity provide numerous ...
Assessing the Ability of an Online Education Program to Modify Patient Expectations of Total Knee Arthroplasty Outcomes: Protocol for a Randomized Controlled Trial
Assessing the Ability of an Online Education Program to Modify Patient Expectations of Total Knee Arthroplasty Outcomes: Protocol for a Randomized Controlled Trial
Background: Patient satisfaction with total knee arthroplasty (TKA) is strongly influenced by alignment between expectatio...
Artificial Intelligence–Assisted Image Extraction in Neonatal Echocardiography for Congenital Heart Disease Diagnosis in Sub-Saharan Africa: Protocol for Model Development
Artificial Intelligence–Assisted Image Extraction in Neonatal Echocardiography for Congenital Heart Disease Diagnosis in Sub-Saharan Africa: Protocol for Model Development
Background: Sub-Saharan Africa (SSA) bears the highest global burden of under-5 mortality, with congenital heart disease (...
Efficacy of a Ready-to-Feed Starter Liquid Infant Formula Containing 2-Fucosyllactose and Lacto-N-Neotetraose in Chinese Infants: Protocol for a Double Blind, Randomized Controlled Trial
Efficacy of a Ready-to-Feed Starter Liquid Infant Formula Containing 2-Fucosyllactose and Lacto-N-Neotetraose in Chinese Infants: Protocol for a Double Blind, Randomized Controlled Trial
Background: Bioactive compounds, such as human milk oligosaccharides (HMOs), impact the development of the intestinal micr...
Effect of TikTok on Self-Harm and Suicidal Behavior in the Adolescent Population: Protocol for a Systematic Review
Effect of TikTok on Self-Harm and Suicidal Behavior in the Adolescent Population: Protocol for a Systematic Review
Background: Social media use among adolescents and young adults has increased exponentially over the last decade, with Tik...
Implementation, Experiences, Impact, and Costs of Artificial Intelligence in Chest Diagnostics: Protocol for a Mixed Methods Evaluation
Implementation, Experiences, Impact, and Costs of Artificial Intelligence in Chest Diagnostics: Protocol for a Mixed Methods Evaluation
Background: The ability to perform complex tasks has seen artificial intelligence (AI) used to support radiology in clinic...
Development of an Intervention for Managing Adolescent Anxiety Using Community-Based Participatory Methods: Protocol
Development of an Intervention for Managing Adolescent Anxiety Using Community-Based Participatory Methods: Protocol
Background: Youth of color that live in urban communities, face disproportionate anxiety levels due to systemic inequities...
Moringa oleifera Supplementation for Reducing Heavy Metal Toxicity and Oxidative Stress in Pregnant Women: Protocol for a Nonrandomized Trial Study
Moringa oleifera Supplementation for Reducing Heavy Metal Toxicity and Oxidative Stress in Pregnant Women: Protocol for a Nonrandomized Trial Study
Background: Heavy metals present in the environment, including lead, cadmium, and mercury, pose significant health risks t...
Developing a Core Outcome Set and a Core Outcome Measurement Set for Studies Evaluating Interventions to Minimize Physical Restraint Use in Adult Intensive Care Units: Protocol for a Modified Delphi Study
Developing a Core Outcome Set and a Core Outcome Measurement Set for Studies Evaluating Interventions to Minimize Physical Restraint Use in Adult Intensive Care Units: Protocol for a Modified Delphi Study
Background: Heterogeneity in outcome selection and measurement methods has been noted in studies examining the minimizatio...
Developing a Multisensor-Based Machine Learning Technology (Aidar Decompensation Index) for Real-Time Automated Detection of Post–COVID-19 Condition: Protocol for an Observational Study
Developing a Multisensor-Based Machine Learning Technology (Aidar Decompensation Index) for Real-Time Automated Detection of Post–COVID-19 Condition: Protocol for an Observational Study
Background: Post–COVID-19 condition is emerging as a new epidemic, characterized by the persistence of COVID-19 symptoms b...
Stress and Hypertension Among African American Female Family Caregivers of Persons Living With Alzheimer Disease and Related Dementias: Protocol for a Pilot Internet-Based Randomized Controlled Trial
Stress and Hypertension Among African American Female Family Caregivers of Persons Living With Alzheimer Disease and Related Dementias: Protocol for a Pilot Internet-Based Randomized Controlled Trial
Background: Caregivers of persons with Alzheimer disease and related dementias (ADRD) neglect their health, including by i...
Efficacy of a Web-Based Integrated Growth Mindset Intervention on Reducing Anxiety Among Social Work and Counseling Practicum Trainees: Protocol for a 2-Arm Randomized Controlled Trial
Efficacy of a Web-Based Integrated Growth Mindset Intervention on Reducing Anxiety Among Social Work and Counseling Practicum Trainees: Protocol for a 2-Arm Randomized Controlled Trial
Background: Practicum is indispensable for the development of professional practitioners; yet, trainees may encounter psyc...
Lung Cancer Screening in Family Members and Peers of Patients With Lung Cancer: Protocol for a Prospective Cohort Study
Lung Cancer Screening in Family Members and Peers of Patients With Lung Cancer: Protocol for a Prospective Cohort Study
Background: Low-dose computed tomography (LDCT) screening is promising for the early detection of lung cancer (LC) and the...
Development of a Framework for Youth- and Family-Specific Engagement in Research: Proposal for a Scoping Review and Qualitative Descriptive Study
Development of a Framework for Youth- and Family-Specific Engagement in Research: Proposal for a Scoping Review and Qualitative Descriptive Study
Background: Youth and families play an indispensable role in health research, given their unique lived experiences and exp...
Evaluation of the Clinical Nursing Effects of a Traditional Chinese Medicine Nursing Program Based on Care Pathways for Patients With Type 2 Diabetes: Protocol for a Randomized Controlled Clinical Trial
Evaluation of the Clinical Nursing Effects of a Traditional Chinese Medicine Nursing Program Based on Care Pathways for Patients With Type 2 Diabetes: Protocol for a Randomized Controlled Clinical Trial
Background: To improve the performance of health care institutions, reduce overmedication, and minimize the waste of medic...
Ayurveda Management of Menorrhagia (Raktapradara): Protocol for a Randomized Controlled Trial
Ayurveda Management of Menorrhagia (Raktapradara): Protocol for a Randomized Controlled Trial
Background: In India, heavy menstrual bleeding or menorrhagia (Raktapradara) constitutes about 15% to 20% of all gynecolog...
Examining Quality of Work Life in Atlantic Canadian Long-Term Care Homes: Protocol for a Cross-Sectional Survey Study
Examining Quality of Work Life in Atlantic Canadian Long-Term Care Homes: Protocol for a Cross-Sectional Survey Study
Background: The Canadian long-term care (LTC) workforce cares for increasingly complex residents. With greater care needs ...
Assessment and Intervention for Diabetes Distress in Primary Care Using Clinical and Technological Interventions: Protocol for a Single-Arm Pilot Trial
Assessment and Intervention for Diabetes Distress in Primary Care Using Clinical and Technological Interventions: Protocol for a Single-Arm Pilot Trial
Background: Diabetes distress (DD) is a common emotional response to living with diabetes. If not addressed, DD can have n...
Treatments for Trauma-Induced Coagulopathy: Protocol for a Systematic Review and Meta-Analysis
Treatments for Trauma-Induced Coagulopathy: Protocol for a Systematic Review and Meta-Analysis
Background: Trauma-induced coagulopathy (TIC) is a common and potentially life-threatening coagulopathy as a result of tra...
Economic Burden of Mosquito-Borne Diseases in Low- and Middle-Income Countries: Protocol for a Systematic Review
Economic Burden of Mosquito-Borne Diseases in Low- and Middle-Income Countries: Protocol for a Systematic Review
Background: Globally, among all the vector-borne diseases, mosquito-borne diseases are responsible for a substantial numbe...
AI Conversational Agent to Improve Varenicline Adherence: Protocol for a Mixed Methods Feasibility Study
AI Conversational Agent to Improve Varenicline Adherence: Protocol for a Mixed Methods Feasibility Study
Background: Varenicline is a pharmacological intervention for tobacco dependence that is safe and effective in facilitatin...
Repetitive Transcranial Magnetic Stimulation With and Without Text4Support for the Treatment of Resistant Depression: Protocol for a Patient-Centered Multicenter Randomized Controlled Pilot Trial
Repetitive Transcranial Magnetic Stimulation With and Without Text4Support for the Treatment of Resistant Depression: Protocol for a Patient-Centered Multicenter Randomized Controlled Pilot Trial
Background: Treatment-resistant depression (TRD) is the inability of a patient with major depressive disorder (MDD) to acc...
Postpandemic Evaluation of the Eco-Efficiency of Personal Protective Equipment Against COVID-19 in Emergency Departments: Proposal for a Mixed Methods Study
Postpandemic Evaluation of the Eco-Efficiency of Personal Protective Equipment Against COVID-19 in Emergency Departments: Proposal for a Mixed Methods Study
Background: The COVID-19 pandemic has had a profound impact on emergency department (ED) care in Canada and around the wor...
Analgesic Effect of Intraoperative Intravenous S(+)-Ketamine During Total Knee Arthroplasty Surgery: Study Protocol for a Randomized Controlled Clinical Trial
Analgesic Effect of Intraoperative Intravenous S(+)-Ketamine During Total Knee Arthroplasty Surgery: Study Protocol for a Randomized Controlled Clinical Trial
Background: Total knee arthroplasty (TKA) is currently the main treatment for end-stage knee disease. The number of cases ...
Investigating the Impact of Automation on the Health Care Workforce Through Autonomous Telemedicine in the Cataract Pathway: Protocol for a Multicenter Study
Investigating the Impact of Automation on the Health Care Workforce Through Autonomous Telemedicine in the Cataract Pathway: Protocol for a Multicenter Study
Background: While digital health innovations are increasingly being adopted by health care organizations, implementation i...
Implications of Agile Values in Software Engineering for Agility in Breast Cancer Treatment: Protocol for a Comparative Study
Implications of Agile Values in Software Engineering for Agility in Breast Cancer Treatment: Protocol for a Comparative Study
Background: Breast cancer treatment has been described as a dynamic and patient-centered approach that emphasizes adaptabi...
A Neuro-Influence Experiment to Evaluate the Persuasiveness of Pre-Exposure Prophylaxis Promotion Messages Among Men Who Have Sex With Men: Protocol for a Randomized Controlled Trial
A Neuro-Influence Experiment to Evaluate the Persuasiveness of Pre-Exposure Prophylaxis Promotion Messages Among Men Who Have Sex With Men: Protocol for a Randomized Controlled Trial
Background: Pre-exposure prophylaxis (PrEP) is recommended by the US Centers for Disease Control and Prevention, but behav...
Phenotypic Environmental Sensitivity and Mental Health During Pregnancy and Post Partum: Protocol for the Experiences of Pregnancy Longitudinal Cohort Study
Phenotypic Environmental Sensitivity and Mental Health During Pregnancy and Post Partum: Protocol for the Experiences of Pregnancy Longitudinal Cohort Study
Background: Mental health problems during pregnancy and post partum are common and associated with negative short- and lon...
Implementation of Competency-Based Education for Quality Midwifery Programs in Africa: Protocol for a Scoping Review
Implementation of Competency-Based Education for Quality Midwifery Programs in Africa: Protocol for a Scoping Review
Background: Competency-based education (CBE) for midwifery programs is a system of academic instruction and evaluation tha...
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