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Malignant Pleural Mesothelioma (MPM) Evaluation with [C]-Methionine PET/CT Before and After Talc Pleurodesis
Malignant Pleural Mesothelioma (MPM) Evaluation with [C]-Methionine PET/CT Before and After Talc Pleurodesis
Malignant pleural mesothelioma (MPM) poses an imaging challenge that requires special attention, especially in patients wh...
Value of Imaging Parameters of [F]FDG PET/CT and Serological Indices in Predicting Lymph Node Metastasis in Intrahepatic Cholangiocarcinoma
Value of Imaging Parameters of [F]FDG PET/CT and Serological Indices in Predicting Lymph Node Metastasis in Intrahepatic Cholangiocarcinoma
This study aimed to evaluate the value of [18F]FDG PET/CT parameters and serological indices in predicting lymph node meta...
Photoacoustic Imaging of Muscle Tissue Oxygenation as a Noninvasive Biomarker in Mouse Models of Sickle Cell Disease
Photoacoustic Imaging of Muscle Tissue Oxygenation as a Noninvasive Biomarker in Mouse Models of Sickle Cell Disease
To develop and validate photoacoustic imaging (PAI) as a method to assess hemoglobin counts and muscle tissue oxygen satur...
Magnetically Controlled Nanocarriers for Site-Specific Drug Delivery and Theranostics in Cancer Precision Medicine
Magnetically Controlled Nanocarriers for Site-Specific Drug Delivery and Theranostics in Cancer Precision Medicine
The growing demand for precision oncology has intensified interest in magnetically controlled nanocarriers (MCNCs) as vers...
The Binding of the High Affinity Radioligand Fallypride to the D2-dopamine Receptor is Sensitive to Injected Mass – a PET Study in Rodents
The Binding of the High Affinity Radioligand Fallypride to the D2-dopamine Receptor is Sensitive to Injected Mass – a PET Study in Rodents
Fallypride is a widely used high affinity radioligand for quantification of D2-dopamine receptor binding in small animal P...
Comparison of [F]FDG and [F]PSMA-1007 PET/CT in the Evaluation of Muscle-Invasive Bladder Cancer: A Pilot Feasibility Study
Comparison of [F]FDG and [F]PSMA-1007 PET/CT in the Evaluation of Muscle-Invasive Bladder Cancer: A Pilot Feasibility Study
To compare the diagnostic performance of [18F]FDG and [18F]PSMA‑1007 PET/CT for detecting primary tumors, regional l...
Astrocyte Activation Persists after Recovery of Myelin and Motor Deficits in the Cuprizone Model: a Longitudinal PET and CNS Tissue Analysis Study
Astrocyte Activation Persists after Recovery of Myelin and Motor Deficits in the Cuprizone Model: a Longitudinal PET and CNS Tissue Analysis Study
The cuprizone (CPZ) mouse model for multiple sclerosis enables researchers to investigate the underlying mechanisms of dem...
Comparison of [F]DPA-814 with [F]DPA-714 for TSPO Imaging in an Experimental Model
Comparison of [F]DPA-814 with [F]DPA-714 for TSPO Imaging in an Experimental Model
[18F]DPA-714 is a valuable tracer for studying (neuro)inflammation, with well-characterized tracer kinetics and an establi...
Preclinical Study of Radiolabeled LyP-1 for Detecting Sunitinib-induced Changes in the Tumor Microenvironment and Synergistic Antitumor Effects in Triple-negative Breast Cancer
Preclinical Study of Radiolabeled LyP-1 for Detecting Sunitinib-induced Changes in the Tumor Microenvironment and Synergistic Antitumor Effects in Triple-negative Breast Cancer
Sunitinib is an anti-angiogenic drug that can induce drug resistance characterized by hypoxia. We aimed to synthesize two ...
Tracking Modalities for Oncolytic Reovirus: Principles, Clinical Applications, and Translational Integration
Tracking Modalities for Oncolytic Reovirus: Principles, Clinical Applications, and Translational Integration
Oncolytic reovirus, particularly Pelareorep, is a promising cancer therapeutic due to selective replication in Ras-activat...
An Optimized Fast Track Protocol to Enhance the Image Quality of 18F-FDG PET Myocardial Viability Imaging in Diabetic CAD Patients: A Randomized Controlled Trial
An Optimized Fast Track Protocol to Enhance the Image Quality of 18F-FDG PET Myocardial Viability Imaging in Diabetic CAD Patients: A Randomized Controlled Trial
Standard ASNC guidelines for 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) myocardial viability imagin...
Prospective Pilot Study of C-acetate and F-FDG with PET/CT and PET/MRI for Lesion Detection in Multiple Myeloma
Prospective Pilot Study of C-acetate and F-FDG with PET/CT and PET/MRI for Lesion Detection in Multiple Myeloma
To compare the diagnostic performance of 11C-acetate and 18F-FDG across hybrid PET/CT and PET/MRI platforms in patients wi...
Accurate Reference Region Calculation in Mouse Brain [F]fallypride Studies
Accurate Reference Region Calculation in Mouse Brain [F]fallypride Studies
Quantification of the dopamine D2/3 receptors tracer [18F]fallypride is usually performed by defining the cerebellum (CB) ...
Quantitative [F]PSMA-1007 PET in Treatment Response Monitoring of Brain Metastases from Non-small Cell Lung Cancer
Quantitative [F]PSMA-1007 PET in Treatment Response Monitoring of Brain Metastases from Non-small Cell Lung Cancer
Prostate-specific membrane antigen (PSMA) is expressed in several solid tumours, including brain metastases (BMs) from lun...
Estimation and Correction of the Partial Volume Effect Using Personalized Phantoms of Lymph Node Metastases in Lutetium 177 SPECT/CT Dosimetry
Estimation and Correction of the Partial Volume Effect Using Personalized Phantoms of Lymph Node Metastases in Lutetium 177 SPECT/CT Dosimetry
This study aims to quantify and to correct for partial volume effect (PVE) in lymph node metastases of prostate cancer (PC...
Dual Quantification of Skeletal Muscle Perfusion and Metabolism in a Porcine Model of Peripheral Artery Disease Using Multiparametric F-FDG PET Imaging
Dual Quantification of Skeletal Muscle Perfusion and Metabolism in a Porcine Model of Peripheral Artery Disease Using Multiparametric F-FDG PET Imaging
A standard imaging strategy for quantifying skeletal muscle perfusion in peripheral artery disease (PAD) does not exist, a...
Transporter-Mediated Hepatic Uptake of EOB-DTPA and BOPTA Is Largely Independent of Chelated Metal
Transporter-Mediated Hepatic Uptake of EOB-DTPA and BOPTA Is Largely Independent of Chelated Metal
Metal chelates play a crucial role in diagnostic imaging and radiotherapy. While gadolinium-based chelates are widely used...
Diagnostic Performance of Somatostatin Receptor-directed PET/CT for Tumor-induced Osteomalacia
Diagnostic Performance of Somatostatin Receptor-directed PET/CT for Tumor-induced Osteomalacia
To evaluate the efficacy of somatostatin receptor (SSTR)-directed PET/CT in localizing phosphaturic mesenchymal tumors (PM...
Clinical Effectiveness of miR-760 to Distinguish Benign and Malignant Pulmonary Nodules on the Basis of Low-Dose Spiral CT Imaging
Clinical Effectiveness of miR-760 to Distinguish Benign and Malignant Pulmonary Nodules on the Basis of Low-Dose Spiral CT Imaging
The differential diagnosis of benign and malignant pulmonary nodules is a key problem in clinical diagnosis. Low-dose spir...
Local Infusing Antiplatelet Microspheres to Prevent Thrombosis Post-PCI: a Feasibility Study in Rabbit Aorta
Local Infusing Antiplatelet Microspheres to Prevent Thrombosis Post-PCI: a Feasibility Study in Rabbit Aorta
After percutaneous coronary intervention (PCI), dual antiplatelet therapy (DAPT) is required to prevent thrombosis, but sy...
Preclinical Evaluation of Novel SGLT2-Targeted Near-Infrared Optical Imaging Agent for Early-Stage Pulmonary Adenocarcinoma
Preclinical Evaluation of Novel SGLT2-Targeted Near-Infrared Optical Imaging Agent for Early-Stage Pulmonary Adenocarcinoma
Lung cancer is increasingly diagnosed at early stages, but intraoperative localization of early lesions remains challengin...
Development and Evaluation of a Vinyl Sulfone-Based Fluorine-18 Labeling Method for Constructing PSMA-targeted Prostate Cancer Imaging Agents
Development and Evaluation of a Vinyl Sulfone-Based Fluorine-18 Labeling Method for Constructing PSMA-targeted Prostate Cancer Imaging Agents
Since prostate-specific membrane antigen (PSMA) is widely expressed in nearly all stages of prostate cancer (PCa), PSMA tr...
In vivo Multimodal Magnetic Particle Imaging for Early Detection of Ischemic Stroke in Tree Shrews
In vivo Multimodal Magnetic Particle Imaging for Early Detection of Ischemic Stroke in Tree Shrews
Ischemic stroke is a significant threat to human life and health, and timely diagnosis is essential for improving patient ...
PET Study of S1PR1 Expression in Rodent Model of Myocardial Infarction
PET Study of S1PR1 Expression in Rodent Model of Myocardial Infarction
Acute myocardial infarction (MI) is a leading cause of morbidity and mortality worldwide. Sphingosine-1-phosphate (S1P) is...
Enhancing the Half-Life of ODAP-Urea Based Radioligands by Incorporating Albumin-Binding Moieties
Enhancing the Half-Life of ODAP-Urea Based Radioligands by Incorporating Albumin-Binding Moieties
Prostate-specific membrane antigen-targeted radioligand therapy (PSMA-RLT) is a promising approach to treating me...
Reengineered Anti-CD4 Cys-diabody Variants for Zr-immunoPET of CD4 T Cells in Immunocompetent Mice
Reengineered Anti-CD4 Cys-diabody Variants for Zr-immunoPET of CD4 T Cells in Immunocompetent Mice
CD4+ T cells (T helper and T reg) play an important role in the immune system and are influential in autoimmune diseases (...
CREBBP Mutation as a Culprit for Negative SSTR2 PET in Neuroendocrine Tumors
CREBBP Mutation as a Culprit for Negative SSTR2 PET in Neuroendocrine Tumors
This study aimed to elucidate the molecular and genetic factors contributing to negative 68Ga-DOTATATE PET imaging in neur...
Fibrotic Disease: from Signaling Pathways and Biomarkers to Molecular Imaging
Fibrotic Disease: from Signaling Pathways and Biomarkers to Molecular Imaging
Fibrotic diseases are characterized by excessive accumulation of extracellular matrix (ECM) components following tissue in...
Evaluation of Indocyanine Green Derivatives with Sulfonic Acid and Carboxylic Acid Groups at the Benzoindolenine Moiety for Antibody-Based Tumor Imaging
Evaluation of Indocyanine Green Derivatives with Sulfonic Acid and Carboxylic Acid Groups at the Benzoindolenine Moiety for Antibody-Based Tumor Imaging
In target-specific cancer imaging, antibodies and their fragments are conjugated with fluorescent dyes to work as targetin...
PET Imaging of Diabetes-Induced Alterations in Metabolism and Immune Activation
PET Imaging of Diabetes-Induced Alterations in Metabolism and Immune Activation
Obesity and type 2 diabetes (T2D) influence the tumor microenvironment by altering glucose metabolism, which has been show...
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