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Exploring the immune-boosting and hepatoprotective potential of Allium jesdianum against cyclophosphamide-induced toxicity in mice: A promising approach for immunomodulation
Objective: Cyclophosphamide (CTX) is a potent chemotherapy drug for treating cancer, but its use is limited due to its tox...
Licorice extract and carbenoxolone protect PC12 cells against serum/glucose deprivation-induced apoptosis through modulation of caspase-3 and PARP activation
Objective: Serum/glucose deprivation in cultured PC12 cells is considered an appropriate model for investigating detailed ...
Methanolic extract of Justicia secunda ameliorates the cyclophosphamide-induced hepatic and renal failures in rats
Objective: This study determined the effect of the methanolic extract of Justicia secunda against cyclophosphamide-instiga...
Impact of strawberry consumption on blood pressure in adults: GRADE-assessed systematic review and dose-response meta-analysis of data from randomized controlled trials
Objective: This systematic review and meta-analysis aimed to assess the impact of strawberry (Fragaria x ananassa) consump...
Inhibition of mast cell activation via MRGPRX2 receptor by Curcuma mangga and Sonchus arvensis water suspensions: An in vitro study
Objective: Traditional medicine is often used to relief pain, but its use is frequently not supported by appropriate scien...
Phenolic screening, antioxidant activity and diuretic effect of Moroccan Pinus pinaster Bark extract
Objective: This study aims to evaluate the chemical composition antioxidant activity, and diuretic effects of Moroccan Pin...
The relaxant effect of the extract of Crocus sativus petal on Wistar rats airway smooth muscle and its possible mechanisms
Objective: Obstructive pulmonary diseases are characterized by airflow limitation secondary to airway wall thickening, air...
Effects of royal jelly consumption on inflammation and oxidative stress: A systematic review and meta-analysis of randomized controlled trials
Objective: This systematic review and meta-analysis examines the impact of royal jelly (RJ) on inflammation and oxidative ...
The effects of an Aloe-based polyherbal formulation on fertility parameters in male rats
Objective: Aloe dry juice as a purgative agent is widely used in phytotherapy. In Iranian traditional medicine to decrease...
Signaling pathway in breast cancer therapy
Objective: This research attempted to increase the bioactivity and solubility and reduce the side effects of Tamoxifen (TM...
Antidiabetic effects of Peganum harmala seed extract on streptozotocin-induced diabetes in rats
Objective: Diabetes, a chronic metabolic disease, has many complex complications and an increasing prevalence in various s...
The hydroalcoholic extract of Nasturtium officinale protectively inhibits apoptotic and inflammatory pathways in hepato- and nephrotoxicity: An in vivo study
Objective: Nasturtium officinale (N. officinale (NO)) has been widely used in traditional medicine. This study investigate...
Protective effect of menthol against diethylnitrosamine-induced hepatocellular carcinoma in mice by downregulating CTNNB1 and HIF-1α
Objective: This study examined the impact of menthol, a natural monoterpene, on diethylnitrosamine (DEN)-induced molecular...
Effects of sumac aqueous extract along with eating and drinking modification on functional dyspepsia symptoms in comparison with omeprazole: An open-label, randomized, controlled clinical trial
Objective: Functional dyspepsia (FD), a common gastrointestinal problem. The aim of the study was to evaluate the influenc...
The effects of saffron supplementation on inflammatory factors and clinical outcomes in sepsis patients admitted to the intensive care unit (ICU): Study protocol for a double-blind randomized controlled clinical trial
Objective: Research studies have examined saffron's effects on inflammation, infection, and oxidative stress. Neverth...
Investigating the potential effects of olive leaves and ginger rhizome extracts on kidney and liver functions in alloxan-induced diabetic rats
Objective: Although there are many drugs on the shelves of pharmacies to manage diabetes mellitus (DM), many people around...
The role of Anvillea garcinii and its compounds in health and disease: An overview
Objective: This scoping review aims to examine the potential health benefits of Anvillea garcinii and its compounds and pr...
Atorvastatin and flaxseed dietary treatments improve dyslipidemia and liver injuries in a diet-induced rat model of non-alcoholic fatty liver disease
Objective: Non-alcoholic fatty liver disease (NAFLD) as the most common chronic liver disease is associated with metabolic...
Preventive and therapeutic effects of Nasturtium officinale hydroalcoholic extract on cyclophosphamide-induced testicular toxicity in rats
Objective: Cyclophosphamide (Cy) as an alkylating chemotherapeutic agent with broad-spectrum efficacy in cancer treatment....
Neuroprotective effects of hesperidin and auraptene on 6-hydroxydopamine-induced neurodegeneration in SH-SY5Y cells
Objective: Destruction of dopaminergic neurons causes diseases. Various compounds with neuroprotective and antioxidant pro...
Therapeutic potency of curcumin on radiodermatitis: A systematic review
Objective: Radiodermatitis (RD) is a frequent adverse event of radiotherapy (RT).  Currently, there is no consensus and ap...
A preliminary report comparing the effect of Asafoetida with oral contraceptive on polycystic ovarian syndrome in a double-blind randomized trial
Objective: Polycystic ovarian syndrome (PCOS) is the most common cause of infertility and endocrine disorders in women of ...
Investigation of the neuroprotective effect of crocin against electromagnetic field-induced cerebellar damage in male Balb/c mice
Objective: Mobile devices are sources of electromagnetic fields  (EMFs) that cause increasing concern among scientists ab...
Concomitant administration of resveratrol and resistance training ameliorates acrylamide-induced spatial learning impairment in rats
Objective: The present study examined effects of resistance training (RT) and resveratrol (RES) alone and together on acry...
Silibinin improved the function of T cells in peripheral blood mononuclear cells (PBMCs) co-cultured with U-87 MG cell line
Objective: Silibinin has exhibited antitumor activities. However, there are few reports about the immunomodulatory propert...
Quercetin may reduce the risk of developing the symptoms of COVID-19
Objective: Recent evidence reported that some dietary compounds like quercetin and apigenin as the most well-known flavono...
The effects of swimming training at different temperatures along with cinnamon supplementation on liver enzymes and thyroid hormones in diabetic rats
Objective:The aim of this study was to investigate the effects of swimming (S) training in water at 5°C (S5C) and 35°C (S3...
Britannin suppresses MCF-7 breast cancer cell growth by inducing apoptosis and inhibiting autophagy
Objective: Breast cancer is the main reason for cancer-related death in women. Britannin is a sesquiterpene lactone compou...
The modulating effects of astaxanthin on apoptosis in women with polycystic ovarian syndrome: Arandomized clinical trial
Objective: Astaxanthin (ASX) is a lipid-soluble keto-carotenoid with several biological effects. These effects may benefit...
Naringin mitigates testicular injury and associated neuronal toxicity in lead-exposed cockerel chicks
Objective: Lead (Pb) poisoning affects multiple organs including the reproductive system. The experiment was performed to ...
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