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Synergistic effects of herbal extracts and nanoparticles in skin damage repair: A comprehensive review
Objective: Today, applying herbal extracts to treat skin damage has become widespread and it is supported by numerous stud...
Evaluation of the effects of Asparagus racemosus extract (ARova5X) supplementation on postmenopausal discomfort
Objective: Menopause is a critical physiological transition often associated with a spectrum of health challenges such as ...
Impact of green tea on obesity-related hormones in postmenopausal women: A systematic review and meta-analysis of randomized controlled trials
Objective: Menopause leads to hormonal changes that increase visceral fat, raising risks for metabolic disorders and breas...
Therapeutic effects of Zataria multiflora Boiss. extract-loaded chitosan nanoparticles against asthma in rats
Objective: Asthma is one of the most common chronic inflammatory disorders worldwide. Zataria multiflora Boiss., widely us...
Lycopene suppresses α-cypermethrin nephrotoxicity: An insight into its modulatory effect on oxidative stress-mediated pro-inflammation, DNA damage and caspase apoptosis in Wistar rats
Objective: Cypermethrin (CPM) is a synthetic pyrethroid pesticide with ubiquitous use in agriculture, but well associated ...
Effect of hydroalcoholic extracts of Quercus brantii and Salvia officinalis on the expression of wound healing and anti-inflammatory factors in human fibroblast cells
Objective: Based on research regarding the regenerative properties of Quercus brantii in wound healing and the anti-inflam...
Beneficial effects of berberine and 6-gingerol against global cerebral ischemia: Insights from stereological, behavioral, and antioxidant enzyme activity
Objective: Global cerebral ischemia (GCI) severely impacts brain function, leading to cognitive impairments and neuronal d...
Investigation of the co-administration of flaxseed supplementation with high-intensity interval training, resistance training, or combined training on hematological indices and kidney health in fructose/CCl4-induced NAFLD in rats
Objective: Types of exercise training and flaxseed are beneficial approaches to improve non-alcoholic fatty liver disease ...
The hepatoprotective impacts of Citrullus colocynthis seeds extract on type 1 diabetes-induced liver inflammation and oxidative stress in rats: The role of nrf2/keap1 pathway
Objective: Type 1 Diabetes (T1D) induces several consequences including hepatic damage resulting from oxidative stress and...
Mistletoe extract (Iscador®) in cancer patients undergoing chemotherapy for prostate and bladder tumors: A prospective observational study
Objective: While mistletoe (a semi-parasitic evergreen plant) extract is commonly used as a complementary therapy in Europ...
The antidiabetic effects of hesperidin and piperine in streptozotocin-induced diabetic rats
Objective: Diabetes mellitus is a metabolic and chronic condition defined by increased blood glucose concentrations. The p...
Dorema aucheri extract for reducing oxidative stress and kidney injuries in diabetic rats
Objective: Diabetic hyperglycemia causes oxidative stress, contributing to chronic kidney disease (CKD). This study evalua...
The effect of curcumin-piperine supplementation on liver transient elastography and biochemical indices in patients with non-alcoholic fatty liver disease: A randomized controlled trial
Objective: Non-alcoholic fatty liver disease (NAFLD), characterized by an excessive buildup of triglycerides in hepatocyte...
Therapeutic effects of Asafoetida (Ferula foetida oleo-gum-resin) on lung function tests, clinical symptoms, and blood parameters in asthmatic patients
Objective: Asthma is a common chronic disease with a wide global prevalence. In this disease, airway inflammation causes m...
Evaluation of the preventive effect of intravenous trans-sodium crocetinate followed by oral crocetin on contrast-induced nephropathy in patients with chronic kidney disease undergoing coronary angioplasty: A randomized placebo-controlled triple-blind clinical trial
Objective: Contrast media (CM) can potentially cause nephropathy. Trans-sodium crocetinate (TSC) has shown promising antio...
Rhizophora apiculata extracts improved memory function through inhibition of acetylcholinesterase and oxidative stress in scopolamine-induced memory deficits in rats
Objective: This study aims to investigate the neuroprotective, memory enhancement effects and phytochemical profile of Rhi...
Effect of pomegranate seed supplementation on cardiometabolic parameters: A systematic review and meta-analysis of interventional studies
Objective: This systematic review and meta-analysis of interventional studies aimed to investigate cardiometabolic protect...
The efficacy of Hypericum perforatum L. for the treatment of premenstrual syndrome: A systematic review and meta-analysis
Objective: Premenstrual syndrome (PMS) occurs in the luteal phase of the menstrual cycle and is characterized by physical,...
Effect of flaxseed oil supplementation on lipid profile in adults: A systematic review and dose-response meta-analysis of randomized controlled trials
Objective: This study evaluated the effects of flaxseed oil (FO, derived from Linum usitatissimum) supplementation on lipi...
Oren-gedoku-to suppresses hypothalamic adenosine 5′-monophosphate-activated protein kinase activity and olanzapine-induced hyperglycemia
Objective: Atypical antipsychotics such as olanzapine (OLZ) are associated with elevated blood glucose levels. Owing to se...
Exploring the immune-boosting and hepatoprotective potential of Allium jesdianum against cyclophosphamide-induced toxicity in mice: A promising approach for immunomodulation
Objective: Cyclophosphamide (CTX) is a potent chemotherapy drug for treating cancer, but its use is limited due to its tox...
Licorice extract and carbenoxolone protect PC12 cells against serum/glucose deprivation-induced apoptosis through modulation of caspase-3 and PARP activation
Objective: Serum/glucose deprivation in cultured PC12 cells is considered an appropriate model for investigating detailed ...
Methanolic extract of Justicia secunda ameliorates the cyclophosphamide-induced hepatic and renal failures in rats
Objective: This study determined the effect of the methanolic extract of Justicia secunda against cyclophosphamide-instiga...
Impact of strawberry consumption on blood pressure in adults: GRADE-assessed systematic review and dose-response meta-analysis of data from randomized controlled trials
Objective: This systematic review and meta-analysis aimed to assess the impact of strawberry (Fragaria x ananassa) consump...
Inhibition of mast cell activation via MRGPRX2 receptor by Curcuma mangga and Sonchus arvensis water suspensions: An in vitro study
Objective: Traditional medicine is often used to relief pain, but its use is frequently not supported by appropriate scien...
Phenolic screening, antioxidant activity and diuretic effect of Moroccan Pinus pinaster Bark extract
Objective: This study aims to evaluate the chemical composition antioxidant activity, and diuretic effects of Moroccan Pin...
The relaxant effect of the extract of Crocus sativus petal on Wistar rats airway smooth muscle and its possible mechanisms
Objective: Obstructive pulmonary diseases are characterized by airflow limitation secondary to airway wall thickening, air...
Effects of royal jelly consumption on inflammation and oxidative stress: A systematic review and meta-analysis of randomized controlled trials
Objective: This systematic review and meta-analysis examines the impact of royal jelly (RJ) on inflammation and oxidative ...
The effects of an Aloe-based polyherbal formulation on fertility parameters in male rats
Objective: Aloe dry juice as a purgative agent is widely used in phytotherapy. In Iranian traditional medicine to decrease...
Signaling pathway in breast cancer therapy
Objective: This research attempted to increase the bioactivity and solubility and reduce the side effects of Tamoxifen (TM...
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