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JDB, Vol. 11, Pages 1: Advances in Understanding the Genetic Mechanisms of Zebrafish Renal Multiciliated Cell Development
JDB, Vol. 11, Pages 1: Advances in Understanding the Genetic Mechanisms of Zebrafish Renal Multiciliated Cell Development
Cilia are microtubule-based organelles that project from the cell surface. In humans and other vertebrates, possession of ...
JDB, Vol. 11, Pages 2: Roles for the RNA-Binding Protein Caper in Reproductive Output in Drosophila melanogaster
JDB, Vol. 11, Pages 2: Roles for the RNA-Binding Protein Caper in Reproductive Output in Drosophila melanogaster
RNA binding proteins (RBPs) play a fundamental role in the post-transcriptional regulation of gene expression within the g...
JDB, Vol. 10, Pages 53: The Development of the Chimaeroid Pelvic Skeleton and the Evolution of Chondrichthyan Pelvic Fins
JDB, Vol. 10, Pages 53: The Development of the Chimaeroid Pelvic Skeleton and the Evolution of Chondrichthyan Pelvic Fins
Pelvic girdles, fins and claspers are evolutionary novelties first recorded in jawed vertebrates. Over the course of the e...
JDB, Vol. 10, Pages 52: Life-Saver or Undertaker: The Relationship between Primary Cilia and Cell Death in Vertebrate Embryonic Development
JDB, Vol. 10, Pages 52: Life-Saver or Undertaker: The Relationship between Primary Cilia and Cell Death in Vertebrate Embryonic Development
The development of multicellular organisms requires a tightly coordinated network of cellular processes and intercellular ...
JDB, Vol. 10, Pages 54: Primary Cilia Dysfunction in Neurodevelopmental Disorders beyond Ciliopathies
JDB, Vol. 10, Pages 54: Primary Cilia Dysfunction in Neurodevelopmental Disorders beyond Ciliopathies
Primary cilia are specialized, microtubule-based structures projecting from the surface of most mammalian cells. These org...
JDB, Vol. 10, Pages 51: The Role of Primary Cilia-Associated Phosphoinositide Signaling in Development
JDB, Vol. 10, Pages 51: The Role of Primary Cilia-Associated Phosphoinositide Signaling in Development
Primary cilia are microtube-based organelles that extend from the cell surface and function as biochemical and mechanical ...
JDB, Vol. 10, Pages 50: Activation of Sonic Hedgehog Signaling Promotes Differentiation of Cortical Layer 4 Neurons via Regulation of Their Cell Positioning
JDB, Vol. 10, Pages 50: Activation of Sonic Hedgehog Signaling Promotes Differentiation of Cortical Layer 4 Neurons via Regulation of Their Cell Positioning
Neuronal subtypes in the mammalian cerebral cortex are determined by both intrinsic and extrinsic mechanisms during develo...
JDB, Vol. 10, Pages 49: Organophosphate Insecticide Toxicity in Neural Development, Cognition, Behaviour and Degeneration: Insights from Zebrafish
JDB, Vol. 10, Pages 49: Organophosphate Insecticide Toxicity in Neural Development, Cognition, Behaviour and Degeneration: Insights from Zebrafish
Organophosphate (OP) insecticides are used to eliminate agricultural threats posed by insects, through inhibition of the n...
JDB, Vol. 10, Pages 48: Seeking Sense in the Hox Gene Cluster
JDB, Vol. 10, Pages 48: Seeking Sense in the Hox Gene Cluster
The Hox gene cluster, responsible for patterning of the head–tail axis, is an ancestral feature of all bilateral...
JDB, Vol. 10, Pages 45: Involvement of a Basic Helix-Loop-Helix Gene BHLHE40 in Specification of Chicken Retinal Pigment Epithelium
JDB, Vol. 10, Pages 45: Involvement of a Basic Helix-Loop-Helix Gene BHLHE40 in Specification of Chicken Retinal Pigment Epithelium
The first event of differentiation and morphogenesis in the optic vesicle (OV) is specification of the neural retina (NR) ...
JDB, Vol. 10, Pages 47: Coordination of Cilia Movements in Multi-Ciliated Cells
JDB, Vol. 10, Pages 47: Coordination of Cilia Movements in Multi-Ciliated Cells
Multiple motile cilia are formed at the apical surface of multi-ciliated cells in the epithelium of the oviduct or the fal...
JDB, Vol. 10, Pages 46: Appropriate Amounts and Activity of the Wilms’ Tumor Suppressor Gene, wt1, Are Required for Normal Pronephros Development of Xenopus Embryos
JDB, Vol. 10, Pages 46: Appropriate Amounts and Activity of the Wilms’ Tumor Suppressor Gene, wt1, Are Required for Normal Pronephros Development of Xenopus Embryos
The Wilms’ tumor suppressor gene, wt1, encodes a zinc finger-containing transcription factor that binds to a GC-...
JDB, Vol. 10, Pages 42: Zebrafish Model of Stickler Syndrome Suggests a Role for Col2a1a in the Neural Crest during Early Eye Development
JDB, Vol. 10, Pages 42: Zebrafish Model of Stickler Syndrome Suggests a Role for Col2a1a in the Neural Crest during Early Eye Development
Most cases of Stickler syndrome are due to autosomal-dominant COL2A1 gene mutations leading to abnormal type II collagen. ...
JDB, Vol. 10, Pages 43: Germ Granules in Animal Oogenesis
JDB, Vol. 10, Pages 43: Germ Granules in Animal Oogenesis
In eukaryotic cells, many macromolecules are organized as membraneless biomolecular condensates (or biocondensates). Liqui...
JDB, Vol. 10, Pages 44: Quantitative Experimental Embryology: A Modern Classical Approach
JDB, Vol. 10, Pages 44: Quantitative Experimental Embryology: A Modern Classical Approach
Experimental Embryology is often referred to as a classical approach of developmental biology that has been to some extent...
JDB, Vol. 10, Pages 41: Zebrafish Slit2 and Slit3 Act Together to Regulate Retinal Axon Crossing at the Midline
JDB, Vol. 10, Pages 41: Zebrafish Slit2 and Slit3 Act Together to Regulate Retinal Axon Crossing at the Midline
Slit-Robo signaling regulates midline crossing of commissural axons in different systems. In zebrafish, all retinofugal ax...
JDB, Vol. 10, Pages 40: The Shape of the Jaw—Zebrafish Col11a1a Regulates Meckel’s Cartilage Morphogenesis and Mineralization
JDB, Vol. 10, Pages 40: The Shape of the Jaw—Zebrafish Col11a1a Regulates Meckel’s Cartilage Morphogenesis and Mineralization
The expression of the col11a1a gene is essential for normal skeletal development, affecting both cartilage and bone. Loss ...
JDB, Vol. 10, Pages 38: Tissue Rotation of the Xenopus Anterior–Posterior Neural Axis Reveals Profound but Transient Plasticity at the Mid-Gastrula Stage
JDB, Vol. 10, Pages 38: Tissue Rotation of the Xenopus Anterior–Posterior Neural Axis Reveals Profound but Transient Plasticity at the Mid-Gastrula Stage
The establishment of anterior–posterior (AP) regional identity is an essential step in the appropriate developme...
JDB, Vol. 10, Pages 37: Sculpting an Embryo: The Interplay between Mechanical Force and Cell Division
JDB, Vol. 10, Pages 37: Sculpting an Embryo: The Interplay between Mechanical Force and Cell Division
The journey from a single fertilised cell to a multicellular organism is, at the most fundamental level, orchestrated by m...
JDB, Vol. 10, Pages 35: Feedback Regulation of Signaling Pathways for Precise Pre-Placodal Ectoderm Formation in Vertebrate Embryos
JDB, Vol. 10, Pages 35: Feedback Regulation of Signaling Pathways for Precise Pre-Placodal Ectoderm Formation in Vertebrate Embryos
Intracellular signaling pathways are essential to establish embryonic patterning, including embryonic axis formation. Ecto...
JDB, Vol. 10, Pages 33: Cleft Palate in Apert Syndrome
JDB, Vol. 10, Pages 33: Cleft Palate in Apert Syndrome
Apert syndrome is a rare genetic disorder characterized by craniosynostosis, midface retrusion, and limb anomalies. Cleft ...
JDB, Vol. 10, Pages 32: New Mutations in the 5′ Region of the Notch Gene Affect Drosophila melanogaster Oogenesis
JDB, Vol. 10, Pages 32: New Mutations in the 5′ Region of the Notch Gene Affect Drosophila melanogaster Oogenesis
The Notch pathway is an important and evolutionarily conserved signaling system involved in the development of multicellul...
JDB, Vol. 10, Pages 31: The Role of Protein Kinase CK2 in Development and Disease Progression: A Critical Review
JDB, Vol. 10, Pages 31: The Role of Protein Kinase CK2 in Development and Disease Progression: A Critical Review
Protein kinase CK2 (CK2) is a ubiquitous holoenzyme involved in a wide array of developmental processes. The involvement o...
JDB, Vol. 10, Pages 30: Acetaminophen Disrupts the Development of Pharyngeal Arch-Derived Cartilage and Muscle in Zebrafish
JDB, Vol. 10, Pages 30: Acetaminophen Disrupts the Development of Pharyngeal Arch-Derived Cartilage and Muscle in Zebrafish
Acetaminophen is a common analgesic, but its potential effects on early embryonic development are not well understood. Pre...
JDB, Vol. 10, Pages 29: The Core Splicing Factors EFTUD2, SNRPB and TXNL4A Are Essential for Neural Crest and Craniofacial Development
JDB, Vol. 10, Pages 29: The Core Splicing Factors EFTUD2, SNRPB and TXNL4A Are Essential for Neural Crest and Craniofacial Development
Mandibulofacial dysostosis (MFD) is a human congenital disorder characterized by hypoplastic neural-crest-derived craniofa...
JDB, Vol. 10, Pages 28: The Role of the Histone Variant H2A.Z in Metazoan Development
JDB, Vol. 10, Pages 28: The Role of the Histone Variant H2A.Z in Metazoan Development
During the emergence and radiation of complex multicellular eukaryotes from unicellular ancestors, transcriptional systems...
JDB, Vol. 10, Pages 26: Epigenetics and Early Development
JDB, Vol. 10, Pages 26: Epigenetics and Early Development
The epigenome controls all aspect of eukaryotic development as the packaging of DNA greatly affects gene expression. Epige...
JDB, Vol. 10, Pages 23: Emerging Roles of RNA-Binding Proteins in Neurodevelopment
JDB, Vol. 10, Pages 23: Emerging Roles of RNA-Binding Proteins in Neurodevelopment
Diverse cell types in the central nervous system (CNS) are generated by a relatively small pool of neural stem cells durin...
JDB, Vol. 10, Pages 25: Crucial Convolution: Genetic and Molecular Mechanisms of Coiling during Epididymis Formation and Development in Embryogenesis
JDB, Vol. 10, Pages 25: Crucial Convolution: Genetic and Molecular Mechanisms of Coiling during Epididymis Formation and Development in Embryogenesis
As embryonic development proceeds, numerous organs need to coil, bend or fold in order to establish their final shape. Gen...
JDB, Vol. 10, Pages 24: De Novo Transcriptome Sequencing and Analysis of Differential Gene Expression among Various Stages of Tail Regeneration in Hemidactylus flaviviridis
JDB, Vol. 10, Pages 24: De Novo Transcriptome Sequencing and Analysis of Differential Gene Expression among Various Stages of Tail Regeneration in Hemidactylus flaviviridis
Across the animal kingdom, lizards are the only amniotes capable of regenerating their lost tail through epimorphosis. Of ...
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