SCI Abstract

search
+
Combining Surface Modification and Bioactive Cues to Enhance Medpor® Implant Integration
Combining Surface Modification and Bioactive Cues to Enhance Medpor® Implant Integration
Achieving stable and functional integration of synthetic implants with host tissue remains a key challenge in tissue engin...
Neutral Buoyancy as a Simple Approach to Simulated Microgravity
Neutral Buoyancy as a Simple Approach to Simulated Microgravity
It is well recognized that interesting biological phenomena occur in various organisms in microgravity. However, real micr...
Therapeutic Efficacy of Mesenchymal Stem Cells (MSCs) on Alzheimer’s Disease: Review of Clinical Results
Therapeutic Efficacy of Mesenchymal Stem Cells (MSCs) on Alzheimer’s Disease: Review of Clinical Results
Alzheimer's disease (AD) presents significant unmet medical needs with no effective therapeutic options. Current pharm...
Umbilical Cord Mesenchymal Stem Cells and Wnt Pathway Modulation: A Novel Therapy for Liver Cirrhosis and Steatosis
Umbilical Cord Mesenchymal Stem Cells and Wnt Pathway Modulation: A Novel Therapy for Liver Cirrhosis and Steatosis
The Wnt signalling pathway, one of the key classical stem cell pathways, plays an important role in helping the liver rege...
Polydeoxyribonucleotide (PDRN) in Dentistry: Narrative Review for Mechanisms and Emerging Clinical Applications
Polydeoxyribonucleotide (PDRN) in Dentistry: Narrative Review for Mechanisms and Emerging Clinical Applications
Polydeoxyribonucleotide (PDRN) has emerged as a promising and cost-effective biological agent in regenerative medicine due...
Transcriptomic Profiling Reveals Mechanisms of Anoikis Resistance in Spheroid-Cultured Human Umbilical Cord Mesenchymal Stem Cells
Transcriptomic Profiling Reveals Mechanisms of Anoikis Resistance in Spheroid-Cultured Human Umbilical Cord Mesenchymal Stem Cells
Mesenchymal stem (stromal) cells are a promising cell source for regenerative medicine, but their therapeutic efficacy is ...
Human Amniotic Mesenchymal Stromal Cells Promote Bone Regeneration via Regulating Ameloblastoma-Derived-Bone Marrow Mesenchymal Cells Crosstalk and Autophagy in Ameloblastoma Microenvironment
Human Amniotic Mesenchymal Stromal Cells Promote Bone Regeneration via Regulating Ameloblastoma-Derived-Bone Marrow Mesenchymal Cells Crosstalk and Autophagy in Ameloblastoma Microenvironment
Growing evidence validates the vital function of mesenchymal stem cells (MSCs) in tumor development. Our previous findings...
Dual-Drug Stent with Sirolimus and WKYMVm Promotes Endothelialization and Limits Hyperplasia
Dual-Drug Stent with Sirolimus and WKYMVm Promotes Endothelialization and Limits Hyperplasia
Conventional drug-eluting stents suppress neointimal hyperplasia but delay re-endothelialization, raising long-term safety...
Human Subcutaneous Derived Stromal Vascular Fraction Endothelial Cells Display Venous and Arterial Markers in Culture and 3D Capillaries
Human Subcutaneous Derived Stromal Vascular Fraction Endothelial Cells Display Venous and Arterial Markers in Culture and 3D Capillaries
The Stromal Vascular Fraction (SVF) derived from human subcutaneous fat has attracted pivotal interest in clinical applica...
Therapeutic Effects of N-Acetylcysteine-Primed, Iron Oxide Nanoparticle-Enhanced Mesenchymal Stem Cell Exosomes in Ototoxicity Hearing Loss
Therapeutic Effects of N-Acetylcysteine-Primed, Iron Oxide Nanoparticle-Enhanced Mesenchymal Stem Cell Exosomes in Ototoxicity Hearing Loss
Sensorineural hearing loss caused by ototoxic agents remains irreversible due to the limited regenerative capacity of coch...
Engineering Mesenchymal Stem Cells with Nanomaterials for Tumor Microenvironment Regulation and Precision Therapy
Engineering Mesenchymal Stem Cells with Nanomaterials for Tumor Microenvironment Regulation and Precision Therapy
The tumor microenvironment (TME) is a major obstacle to effective cancer therapy, driving tumor progression, metastasis, a...
Alkaline Phosphatase–Regulated C–C Motif Chemokine Ligand 5 (CCL5) Functions as a Critical Mediator of Hair Follicle Neogenesis
Alkaline Phosphatase–Regulated C–C Motif Chemokine Ligand 5 (CCL5) Functions as a Critical Mediator of Hair Follicle Neogenesis
Alkaline phosphatase (ALP) is a well-established molecular marker of dermal papilla (DP) cells, and its activity closely c...
Development of Lung Mimics Using Homogeneous Pluripotent Stem Cells in Deep-Well Plate with Antioxidant-Enriched Media for Drug Screening and Infectious Disease Research
Development of Lung Mimics Using Homogeneous Pluripotent Stem Cells in Deep-Well Plate with Antioxidant-Enriched Media for Drug Screening and Infectious Disease Research
Organoids are three-dimensional (3D) in vitro cell culture systems that grow and self-organize, with cells differentiating...
Rapid and Efficient Combined Decellularization with Physical, Chemical and Enzymatic Treatment for Production of Bovine-Derived Meniscal Implant to Replace Damaged Meniscus
Rapid and Efficient Combined Decellularization with Physical, Chemical and Enzymatic Treatment for Production of Bovine-Derived Meniscal Implant to Replace Damaged Meniscus
Xenogeneic menisci offer a promising biomaterial with high biocompatibility, closely resembling the native meniscus. Howev...
Biochemical and Mechanical Signal Differentially Contribute to Survival in Surface-Modified Cell Model
Biochemical and Mechanical Signal Differentially Contribute to Survival in Surface-Modified Cell Model
Regenerative cell sources such as bone marrow-multipotent stem cells (BM-MSCs) face poor survival after transplantation du...
Biomimetic Constructs for Achilles Tendon Regeneration and their Translation to Human Medicine
Biomimetic Constructs for Achilles Tendon Regeneration and their Translation to Human Medicine
Achilles tendon injuries are among the most common lower-body tendon injuries, often resulting fromoveruse and repetitive ...
Correction: A 3D Printed Poly(ε-caprolactone)-Collagen Hybrid Mesh (TissueDerm) for Breast Reconstruction after Mastectomy in a Pig Model
Correction: A 3D Printed Poly(ε-caprolactone)-Collagen Hybrid Mesh (TissueDerm) for Breast Reconstruction after Mastectomy in a Pig Model
Characterization of PCL mesh and TissueDerm. A CAD designed PCL mesh B Photograph of 3D printed PCL mesh and TissueDerm C ...
Liraglutide Promoted Osteogenic Differentiation of Dental Pulp Stem Cells via H3K18 Lactylation-Dependent DSPP Activation
Liraglutide Promoted Osteogenic Differentiation of Dental Pulp Stem Cells via H3K18 Lactylation-Dependent DSPP Activation
Dental pulp stem cells (DPSCs) are critical for periodontal tissue regeneration, yet their therapeutic potential is limite...
Recent Progress of Dopamine-Modified Tissue Adhesives for Biomedical Applications in Underwater Environments
Recent Progress of Dopamine-Modified Tissue Adhesives for Biomedical Applications in Underwater Environments
Underwater adhesion of polymeric adhesives is highly desirable in specific applications such as wound dressings, wearable ...
Poly(2-Methacryloxyethyl Phosphorylcholine-Co-Butyl Methacrylate) Coating Enhances Biomimetic Mineralization of Bioglass and Promotes Cellular Proliferation
Poly(2-Methacryloxyethyl Phosphorylcholine-Co-Butyl Methacrylate) Coating Enhances Biomimetic Mineralization of Bioglass and Promotes Cellular Proliferation
Biologically active glasses (BG) are widely studied as potential materials for bone tissue engineering, owing to their cap...
Establishment of Immune-Evasive iPSCs from PBMCs Using B2M Knockout and CD47/HLA-E Overexpression
Establishment of Immune-Evasive iPSCs from PBMCs Using B2M Knockout and CD47/HLA-E Overexpression
Induced pluripotent stem cells (iPSCs) represent a promising source for regenerative therapies, yet allogeneic transplanta...
Angiopoietin-1 and Tie2-Based Dual Cell Therapy Enhances Antiangiogenic Barrier Function in a Retina-Mimetic Model for Neovascular Retinal Disease
Angiopoietin-1 and Tie2-Based Dual Cell Therapy Enhances Antiangiogenic Barrier Function in a Retina-Mimetic Model for Neovascular Retinal Disease
Choroidal neovascularization (CNV) is a major pathological process underlying retinal degenerative diseases such as wet ag...
Effect of Solute Molecular Weights on Mass Transfer within the Rat Lacunar-Canalicular System under Gravity
Effect of Solute Molecular Weights on Mass Transfer within the Rat Lacunar-Canalicular System under Gravity
The lacunar-canalicular system (LCS) serves as the mechanobiological foundation for bone tissue metabolism, mechanotransdu...
Human Nasal Olfactory Stem Cell-Derived Extracellular Vesicles Improve the Repair of Rat Nerves
Human Nasal Olfactory Stem Cell-Derived Extracellular Vesicles Improve the Repair of Rat Nerves
Damage to the peripheral nerve significantly impairs quality and way of life. Despite the slow self-regeneration of the pe...
Angiogenic Ability of Extracellular Vesicles Derived from Angio-miRNA-Modified Mesenchymal Stromal Cells
Angiogenic Ability of Extracellular Vesicles Derived from Angio-miRNA-Modified Mesenchymal Stromal Cells
Regenerative therapy using extracellular vesicles (EVs) is a promising approach for the supportive treatment of chronic li...
Keratin Scaffold Formulation Impacts rhBMP-2 Biodistribution and Bone Regeneration in a Rat Femur Defect Model
Keratin Scaffold Formulation Impacts rhBMP-2 Biodistribution and Bone Regeneration in a Rat Femur Defect Model
Treatment for nonunion in long bones remains a clinical need. Collagen sponges loaded with recombinant human bone morphoge...
Exosome Therapy: A Promising Avenue for Treating Intervertebral Disc Degeneration
Exosome Therapy: A Promising Avenue for Treating Intervertebral Disc Degeneration
The human spine relies on intervertebral discs (IVDs) for support and mobility, functioning as shock absorbers that enable...
Characteristics of 3D-Printed Polycaprolactone Tracheal Scaffolds Implanted
Characteristics of 3D-Printed Polycaprolactone Tracheal Scaffolds Implanted
A 3D-printing technology using polycaprolactone (PCL) has shown promise for the development of patient-customized tracheal...
Three-Dimensional Bioprinting and Infertility-Related Female Reproductive System Diseases: A Review of Current and Future Applications
Three-Dimensional Bioprinting and Infertility-Related Female Reproductive System Diseases: A Review of Current and Future Applications
Infertility has a significant impact on women, affecting them both mentally and physically. Some of the current infertilit...
Human Mesenchymal Stem Cell-Derived Skeletal Muscle Cell Spheroids for Treating Dexamethasone-Induced Sarcopenia
Human Mesenchymal Stem Cell-Derived Skeletal Muscle Cell Spheroids for Treating Dexamethasone-Induced Sarcopenia
Sarcopenia, a musculoskeletal disease associated with aging or certain factors, is characterized by a reduction in muscle ...
Load More
format_indent_increase