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Supraspinatus Muscle Degeneration, Inflammation, and Regeneration Vary By Location in a Rat Model of Severe Rotator Cuff Tear
Degeneration of the human supraspinatus muscle after rotator cuff tendon tear varies by location within the muscle; howeve...
Regenerative Engineering And Translational Medicine
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Phytochemical-Mediated Green Synthesis of ZnO–CuO Nanoparticles from Stem Fibers: Structural, Thermal, and Antibacterial Characterization
The development of sustainable nanomaterials using plant-derived resources has gained increasing attention for biomedical ...
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Effect of Silica-Collagen-Hydroxyapatite Biocomposite Alone and in Conjunction with Homologous Platelet Rich Plasma for the Management of Calvarial Defect in Rat Models
This study was aimed to investigate the bone healing efficacy of a novel biomaterial silica-collagen-hydroxyapatite compos...
Regenerative Engineering And Translational Medicine
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Tailoring Properties of Small-Diameter Vascular Grafts: An In Vivo Study of Polycaprolactone and Polylactic Acid Blends and Copolymers
The increasing prevalence of cardiovascular diseases has heightened the demand for effective small-diameter vascular prost...
Regenerative Engineering And Translational Medicine
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Hydrogel Dressings for Wound Protection under Extreme Conditions: Design, Challenges, and Applications
Wound healing in extreme environments—such as high temperature, humidity, salinity, intense sunlight, and radiation&...
Regenerative Engineering And Translational Medicine
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Synergistic Effects of Kerecis Fish-Skin Dermal Scaffold and Stromal Vascular Fraction (mSVF)
Chronic wounds impose a large socio-economic burden on both patients and healthcare providers. They result from altered ce...
Regenerative Engineering And Translational Medicine
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Mitochondrial Network Enhancing (MiNE) Nanoparticles for the Treatment of Neurodegenerative Disease and the Aging Brain
There is a current surge in the global occurrence of neurodegenerative diseases (ND), a collection of age-related diseases...
Regenerative Engineering And Translational Medicine
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Tracheal Reconstruction Using Hybrid Decellularized-PCL Scaffolds: Two-Stage Heterotopic and Orthotopic Transplantation
Long-segment tracheal defects remain a significant surgical challenge that cannot be treated with conventional tracheal re...
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Transforming Growth Factor Beta 1, Ca15-3, and Serum Retinol Levels as Biomarkers of Disease Progression in Diabetic Nephropathy Associated with Type 2 Diabetes Mellitus
This study investigated the association of transforming growth factor-beta 1 (TGF-β1), cancer antigen 15 −...
Regenerative Engineering And Translational Medicine
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A Comprehensive Review of Polymeric Materials and Scaffold Technologies in 3D Bioprinting for Bone Tissue Engineering
Bone Tissue Engineering focuses on developing biomaterials and regenerative strategies to repair bone defects and restore ...
Regenerative Engineering And Translational Medicine
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Novel Extraction Method of BIS-GMA Resin Free Latex from (Jackfruit) and its Biomedical Applications
Artocarpus (A.) heterophyllus is a member of the Moraceae family, all parts of which contain sticky white latex produced b...
Regenerative Engineering And Translational Medicine
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Kartogenin-loaded Decellularized Wharton’s Jelly for the Chondrogenic Differentiation of Mesenchymal Stem Cells; An In Vitro Study
In the present in vitro study, decellularized Wharton’s jelly (dWJ) scaffolds were loaded with kartogenin (KGN), and...
Regenerative Engineering And Translational Medicine
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Nanoparticles and Nanomaterials for Targeted Drug Delivery: An Updated Review
Typical drug administration methods are often limited by low bioavailability, lack of specificity in biodistribution, rapi...
Regenerative Engineering And Translational Medicine
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Deferoxamine and Mesenchymal Cells along with Acellular Bone Graft Improved Vascularization Marker and Bone Regeneration in Radius Critical-Size Defect of Rat
Critical-sized bone defects do not heal spontaneously and remain a major clinical challenge. Strategies that simultaneousl...
Regenerative Engineering And Translational Medicine
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Bone Marrow Mesenchymal Stem Cell Preconditioning With Alpha Pinene Reverses Ischemia Induced Neuronal Degeneration in Rats
Preconditioned stem cells may offer a promising approach to treat various neurological disorders. Compounds like alpha pin...
Regenerative Engineering And Translational Medicine
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Extracellular Vesicles-Loaded Silk Fibroin Scaffolds for Targeted Therapeutic Delivery
Extracellular vesicles (EVs), are nanovesicles with a complex composition of lipids, proteins, and nucleic acids. These ve...
Regenerative Engineering And Translational Medicine
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Regional SDF-1α Delivery to Injured Rotator Cuff Muscle Causes Localized Changes in Inflammatory Cell Response
Following rotator cuff tendon injury, the corresponding muscle undergoes degeneration, which has been found to occur asymm...
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Passage-Dependent Shifts in the Immunomodulatory and Migratory Properties of Mesenchymal Stem Cell Secretomes in THP-1 Monocytic Cells
Mesenchymal stem cells (MSCs) exert immunomodulatory and regenerative effects primarily through their secretome, which com...
Regenerative Engineering And Translational Medicine
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Targeting Molecular Dysregulation in Diabetic Wound Healing through Nanomaterial-Based Drug Delivery Systems for Improved Therapeutic Outcomes
Diabetic foot ulcers (DFUs) are a serious complication of diabetes mellitus, which is marked by dysfunctional angiogenesis...
Regenerative Engineering And Translational Medicine
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Biocompatible Titania for Drug Delivery and Tissue Engineering
Titanium dioxide (TiO2) has garnered significant attention in biomedical applications, particularly in drug delivery and t...
Regenerative Engineering And Translational Medicine
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Innovative Approaches in Drug Delivery: Cell-Mediated Drug Delivery
Cell-mediated drug delivery is considered a promising therapeutic strategy designed to increase the efficacy of pharmacolo...
Regenerative Engineering And Translational Medicine
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Conductive Scaffolds as Exosome Carrier for Regeneration: State of the Art and Perspectives
Promoting complete regeneration of damaged electroconductive tissues is one of the remaining challenges in tissue engineer...
Regenerative Engineering And Translational Medicine
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Chitosan/β-Glycerophosphate Thermosensitive Aerosol Hydrogel as an Innovative Medical Device for Rapid Hemostasis in Emergency Related Physical Trauma: A Comprehensive Review
Uncontrolled hemorrhage is a leading cause of preventable mortality in trauma cases, necessitating rapid and effective hem...
Regenerative Engineering And Translational Medicine
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Multiple Drug Delivery Ability of Calcium Phosphate Scaffolds promotes Osteogenic Gene Expression in In Vitro Co-culture Model
This study investigates the incorporation of curcumin, resveratrol, and vitamin D3 into polymer-integrated calcium phospha...
Regenerative Engineering And Translational Medicine
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Advancements in Ovarian Tissue Engineering: Strategies for Fertility Preservation and Restoration
Ovarian failure and dysfunction represent significant opportunities for ovarian replacement via ovarian tissue engineering...
Regenerative Engineering And Translational Medicine
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Biomechanical Innovations in Advanced Materials: a Pathway to Regenerative and Biomedical Applications
This review explores recent advances in biomaterials, nanotechnology, and fabrication techniques aimed at improving mechan...
Regenerative Engineering And Translational Medicine
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Treating Post-Cataract Posterior Capsule Opacification: The Relationship Between Myofibroblast Concentration on Lens Capsule Wrinkling
The present study aimed to determine the relationship between the concentration of myofibroblasts on bovine lens capsules ...
Regenerative Engineering And Translational Medicine
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Safety and Biocompatibility of a Spray-Dried Influenza Microparticle Vaccine in Mice
Influenza virus is a persistent source of morbidity and moribundity, and effective disease control requires ever-evolving ...
Regenerative Engineering And Translational Medicine
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Curcumin Delivery in Regenerative Medicine for Alzheimer’s Disease
Curcumin has been widely used as a therapeutic and dietary agent. It possesses several beneficial properties, including th...
Regenerative Engineering And Translational Medicine
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Nanoindentation Characteristics and Cytoskeletal Organization of Stem Cells Toward Cardiomyogenic Differentiation by Electrochemical Stimulations
Electrical field impulses (EF) modulate the behavior of mesenchymal stem cells (MSCs), influencing their differentiation i...
Regenerative Engineering And Translational Medicine
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