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SCI Abstract
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Prognostic implications of tissue-based homologous recombination deficiency in metastatic gastric cancer treated with immune checkpoint inhibitor plus chemotherapy
Homologous recombination deficiency (HRD), a genomic instability phenotype resulting from impaired DNA repair, has been as...
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Circulating tumor DNA-guided response evaluation in patients with previously treated gastroesophageal adenocarcinoma
Systemic treatment offers only modest survival benefits in previously treated metastatic gastroesophageal adenocarcinoma (...
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Feasibility study of cap-assisted endoscopic mucosal resection for gastric adenocarcinoma of fundic gland type
Gastric adenocarcinoma of fundic gland type (GA-FG) is a rare subtype that typically arises in the upper stomach, making e...
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Hospital-based gastric cancer outcomes in the United States (2003–2022): racial and regional disparities
Racial disparities in gastric cancer (GC) outcomes have gained increasing attention in the United States, particularly giv...
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Clinical advantages of robotic gastrectomy for gastric cancer over conventional laparoscopic approach: a retrospective cohort study using a nationwide registry database in Japan
To evaluate contemporary short-term outcomes of robotic gastrectomy (RG) approximately 5 years after its widespre...
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Diagnostic performance of staging laparoscopy after chemotherapy and the prognostic impact of peritoneal disease resolution in advanced gastric cancer
The clinical utility of staging laparoscopy (SL) after chemotherapy for advanced gastric cancer remains unclear. This stud...
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Comparison of oncological outcomes between robotic and laparoscopic surgeries for gastric cancer: a multi-institutional cohort study in Japan
The oncological safety and benefits of robotic gastrectomy (RG) in daily clinical practice remain unknown. This study aime...
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Correction: Resistance to FGFR1-targeted therapy leads to autophagy via TAK1/AMPK activation in gastric cancer
Department of General Surgery, Research Center for Clinical Oncology, The Affiliated Cancer Hospital of Nanjing Medical Un...
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Clinical outcomes of endoscopic resection for remnant gastric cancer: a multicenter prospective cohort study
While the incidence of early-stage remnant gastric cancer (RGC) is increasing, evidence for the validity of endoscopic res...
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A proof-of-concept study of surgical-VLM for surgical support in robotic surgery: contextual benchmarking against ChatGPT-5
Artificial intelligence (AI) has rapidly advanced in surgical applications. However, existing single-modality AI models re...
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Preoperative chemotherapy with docetaxel, oxaliplatin, and S-1 for gastric cancer with extensive lymph node metastasis: 3-year follow-up results from JCOG1704
Prognosis of marginally resectable gastric cancer with extensive lymph node metastasis (ELM) remains poor, even after R0 r...
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Oral vitamin B₁₂ after total gastrectomy for gastric cancer: mapping the evidence
Patients who undergo total gastrectomy lose the ability to produce intrinsic factor and require lifelong supplementation t...
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Correction: An observational study of the effectiveness and safety of nivolumab plus chemotherapy for untreated advanced or recurrent gastric cancer in Japanese real-world settings: the G-KNIGHT study
Department of Clinical Oncology, Aichi Cancer Center Hospital, Aichi, JapanShigenori Kadowaki & Kei MuroDepartment of ...
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Catheter based intraperitoneal chemotherapy using taxane for peritoneal metastases from gastric cancer: from bench to bedside—a narrative review
Peritoneal metastasis (PM) is the most common and clinically devastating mode of spread in Gastric Cancer. Despite advance...
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CXCL12 upregulates PD-L1 expression and promotes M2 polarisation of tumour-associated macrophages to confer anti-PD-1 resistance in gastric cancer
Immunotherapy offers promise for gastric cancer (GC) patients, yet its efficacy is substantially limited by high rates of ...
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rs762855 single nucleotide polymorphism modulates the risk for diffuse-type gastric cancer in females: a genome-wide association study in the Korean population
Intestinal-type gastric cancer (IGC) and diffuse-type gastric cancer (DGC) exhibit different prevalence rates between sexe...
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Differential impact of frailty on surgical and non-surgical site complications in patients with gastric cancer undergoing gastrectomy
The aim of this study was to determine the differential impact of frailty on surgical site complications (SSCs) and non-su...
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Multi-omics sequencing of gastroesophageal junction adenocarcinoma reveals prognosis-relevant key factors and a novel immunogenomic classification
Gastroesophageal junction adenocarcinoma (GEJAC) exhibits distinct molecular characteristics due to its unique anatomical ...
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A novel ypN-TRG staging system for gastric cancer patients after neoadjuvant therapy based on the metro-ticket paradigm: a multicenter and large sample retrospective analysis
Conventional ypT category evaluates the depth of invasion after neoadjuvant therapy (NAT) for gastric cancer (GC) and has ...
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Identification of CD66c as a potential target in gastroesophageal junction cancer for antibody–drug conjugate development
Gastroesophageal junction (GEJ) cancer exhibits unique biological characteristics and currently lacks specific targeted th...
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Genomic landscape and potential therapeutic targets in alpha-fetoprotein-producing gastric cancer
Alpha-fetoprotein-producing gastric carcinoma (AFPGC) is a rare and aggressive subtype of gastric cancer (GC). A comprehen...
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Multiple metachronous foveolar-type gastric adenomas in a -naïve patient with long-term use of a proton pump inhibitor: a case report
A 69-year-old man undergoing long-term administration of a proton-pump inhibitor (PPI) underwent upper endoscopy, which fo...
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Lenvatinib suppress FGF19–FGFR4 signaling to enhance antitumor immune response in gastric cancer
Fibroblast growth factor receptor (FGFR) 4 is overexpressed in gastric cancer (GC) and is a potential therapeutic target f...
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Clinicopathological significance of JAK2, STAT3, and STAT4 expression in patients with gastric solid-type poorly differentiated adenocarcinoma: a retrospective study
The role of janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling remains unclear in gastri...
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Investigating the role of inflammatory cytokines in mediating the effect of gut microbiota on gastrointestinal cancers: a mendelian randomization study
The purpose of this study is to explore the causal relationship between gut microbiota and gastrointestinal (GI) cancers a...
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The relationship between the gastric cancer microbiome and clinicopathological factors: a metagenomic investigation from the 100,000 genomes project and The Cancer Genome Atlas
Findings from previous gastric cancer microbiome studies have been conflicting, potentially due to patient and/or tumor he...
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Spatial organization of B lymphocytes and prognosis prediction in patients with gastric cancer
Within the tumor microenvironment (TME), the association of B lymphocytes (B cells) with prognosis and therapy response in...
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The impact of ADAMTS14 genetic polymorphisms and its function on susceptibility to and prognosis of gastric cancer in a Chinese Han population
Single nucleotide polymorphisms (SNPs) are associated with various diseases, including gastric cancer. The ADAMTS14 gene i...
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Robotic and laparoscopic gastrectomy for gastric cancer: comparative insights into perioperative performance and three-year survival outcomes
The primary treatment for gastric cancer (GC) is surgical resection, particularly for locally advanced cases. While laparo...
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