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SCI Abstract
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rs762855 single nucleotide polymorphism modulates the risk for diffuse-type gastric cancer in females: a genome-wide association study in the Korean population
Intestinal-type gastric cancer (IGC) and diffuse-type gastric cancer (DGC) exhibit different prevalence rates between sexe...
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Differential impact of frailty on surgical and non-surgical site complications in patients with gastric cancer undergoing gastrectomy
The aim of this study was to determine the differential impact of frailty on surgical site complications (SSCs) and non-su...
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Multi-omics sequencing of gastroesophageal junction adenocarcinoma reveals prognosis-relevant key factors and a novel immunogenomic classification
Gastroesophageal junction adenocarcinoma (GEJAC) exhibits distinct molecular characteristics due to its unique anatomical ...
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A novel ypN-TRG staging system for gastric cancer patients after neoadjuvant therapy based on the metro-ticket paradigm: a multicenter and large sample retrospective analysis
Conventional ypT category evaluates the depth of invasion after neoadjuvant therapy (NAT) for gastric cancer (GC) and has ...
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Identification of CD66c as a potential target in gastroesophageal junction cancer for antibody–drug conjugate development
Gastroesophageal junction (GEJ) cancer exhibits unique biological characteristics and currently lacks specific targeted th...
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Genomic landscape and potential therapeutic targets in alpha-fetoprotein-producing gastric cancer
Alpha-fetoprotein-producing gastric carcinoma (AFPGC) is a rare and aggressive subtype of gastric cancer (GC). A comprehen...
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Multiple metachronous foveolar-type gastric adenomas in a -naïve patient with long-term use of a proton pump inhibitor: a case report
A 69-year-old man undergoing long-term administration of a proton-pump inhibitor (PPI) underwent upper endoscopy, which fo...
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Lenvatinib suppress FGF19–FGFR4 signaling to enhance antitumor immune response in gastric cancer
Fibroblast growth factor receptor (FGFR) 4 is overexpressed in gastric cancer (GC) and is a potential therapeutic target f...
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Clinicopathological significance of JAK2, STAT3, and STAT4 expression in patients with gastric solid-type poorly differentiated adenocarcinoma: a retrospective study
The role of janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling remains unclear in gastri...
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Investigating the role of inflammatory cytokines in mediating the effect of gut microbiota on gastrointestinal cancers: a mendelian randomization study
The purpose of this study is to explore the causal relationship between gut microbiota and gastrointestinal (GI) cancers a...
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The relationship between the gastric cancer microbiome and clinicopathological factors: a metagenomic investigation from the 100,000 genomes project and The Cancer Genome Atlas
Findings from previous gastric cancer microbiome studies have been conflicting, potentially due to patient and/or tumor he...
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Spatial organization of B lymphocytes and prognosis prediction in patients with gastric cancer
Within the tumor microenvironment (TME), the association of B lymphocytes (B cells) with prognosis and therapy response in...
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The impact of ADAMTS14 genetic polymorphisms and its function on susceptibility to and prognosis of gastric cancer in a Chinese Han population
Single nucleotide polymorphisms (SNPs) are associated with various diseases, including gastric cancer. The ADAMTS14 gene i...
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Robotic and laparoscopic gastrectomy for gastric cancer: comparative insights into perioperative performance and three-year survival outcomes
The primary treatment for gastric cancer (GC) is surgical resection, particularly for locally advanced cases. While laparo...
Gastric Cancer
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Impact of histologically poorly cohesive phenotype as a prognostic factor in patients with pStage II/III gastric cancer undergoing adjuvant chemotherapy
Few studies have focussed on using histological phenotype to evaluate prognostic factors after adjuvant chemotherapy (AC) ...
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FERMT2 drives anoikis resistance and peritoneal metastasis by enhancing extracellular matrix deposition in gastric cancer
Peritoneal metastasis is a critical step in the progression of gastric cancer (GC), yet its underlying mechanisms remain p...
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Leptomeningeal carcinomatosis in gastric cancer: A Review
Gastric cancer is the fifth most common cancer worldwide and leptomeningeal carcinomatosis (LM) occurs in 0.06% of gastric...
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Appetite-preserving gastrectomy (APG) for esophagogastric junction cancer: preserving the residual stomach as an endocrine organ
Loss of appetite following gastric cancer surgery, particularly total gastrectomy, significantly impacts patient quality o...
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Effects of RAD50 SNP, sodium intake, and H. pylori infection on gastric cancer survival in Korea
Double-strand break repair protein (RAD50) gene plays important roles in genomic integrity, DNA double-strand break repair...
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Gastric tubular adenocarcinoma with diffuse neutrophils infiltrating: characteristics and probable treatment strategy
Gastric adenocarcinoma is a highly heterogeneous malignancy with varying prognoses. In clinicopathological practice, we no...
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Automatic surgical phase recognition-based skill assessment in laparoscopic distal gastrectomy using multicenter videos
Gastric surgery involves numerous surgical phases; however, its steps can be clearly defined. Deep learning-based surgical...
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Helicobacter pylori testing prior to or at gastric cancer diagnosis and survival in a diverse US patient population
Gastric cancer (GC) accounts for the greatest disparity in cancer mortality between Black and White Americans. Although cl...
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5-year follow-up results of a JCOG1104 (OPAS-1) phase III non-inferiority trial to compare 4 courses and 8 courses of S-1 adjuvant chemotherapy for pathological stage II gastric cancer
Postoperative adjuvant chemotherapy with S-1 for 1 year (corresponding to eight courses) is the standard treatment for pat...
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Randomized controlled trial comparing the costs of gastric cancer screening systems between serological risk-based upper gastrointestinal endoscopy and the existing barium photofluorography: gastric cancer screening labeled by serum examination in place of aged gastric cancer organized screening systems (GALAPAGOS study)
Although the risk of gastric cancer can be stratified according to Helicobacter pylori (H. pylori) IgG antibody titer and ...
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Clinical outcomes of Epstein–Barr virus (EBV)-associated metastatic and locally advanced unresectable gastric cancers (GCs) in patients receiving first-line fluoropyrimidine and platinum (FP) doublet chemotherapy
Epstein–Barr virus-associated gastric cancer (EBVaGC) is a distinct molecular subgroup showing excellent outcomes af...
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Efficacy and safety of chemotherapy in young patients with advanced gastroesophageal adenocarcinoma: data from the Spanish AGAMENON-SEOM registry
Gastroesophageal adenocarcinoma in young adults (GCYA) counts for 10–15% of diagnoses. Previous studies have mainly ...
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Collagen-related gene expression level predicts the prognosis and immune therapy response
Gastric cancer patients responded differently to the same treatment strategy and had various prognoses for the lack of bio...
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Ethnic-specific associations between body mass index and gastric cancer: a Mendelian randomization study in European and Korean populations
Given the uncertainties surrounding the associations in previous epidemiological studies, we conducted linear and nonlinea...
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Effect of preoperative chemotherapy on the histopathological classification of gastric cancer
In the era of individualized gastric cancer (GC) treatment, accurate determination of histological subtype becomes increas...
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Identifying the best candidates for reduced port gastrectomy
Previous studies have focused on the non-inferiority of RPG compared with conventional port gastrectomy (CPG); however, we...
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