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The 2021 IXA Keith Reemtsma Lecture: Moving xenotransplantation to the clinic
The 2021 IXA Keith Reemtsma Lecture: Moving xenotransplantation to the clinic
Abstract Keith Reemtsma was a pioneer in xenotransplantation, the Honorary Founding President of the International Xenotra...
Anti‐thymoglobulin induction improves neonatal porcine xenoislet engraftment and survival
Anti‐thymoglobulin induction improves neonatal porcine xenoislet engraftment and survival
Abstract Porcine islet xenotransplantation is a viable strategy to treat diabetes. Its translation has been limited by the...
Transgenic pigs expressing near infrared fluorescent protein—A novel tool for noninvasive imaging of islet xenotransplants
Transgenic pigs expressing near infrared fluorescent protein—A novel tool for noninvasive imaging of islet xenotransplants
Abstract Background Islet xenotransplantation is a promising concept for beta-cell replacement therapy. Reporter genes for...
MRI monitoring of transplanted neonatal porcine islets labeled with polyvinylpyrrolidone‐coated superparamagnetic iron oxide nanoparticles in a mouse model
MRI monitoring of transplanted neonatal porcine islets labeled with polyvinylpyrrolidone‐coated superparamagnetic iron oxide nanoparticles in a mouse model
Abstract Islet transplantation is a potential treatment option for certain patients with type 1 diabetes; however, it stil...
Should you need an organ… Flemish secondary school students’ attitudes toward xenotransplantation and transgenetic organ donation
Should you need an organ… Flemish secondary school students’ attitudes toward xenotransplantation and transgenetic organ donation
Abstract Background The supply of human organs available for transplantation remains grossly inadequate globally. Animal-t...
Initial evidence that blockade of the CD40/CD154 costimulation pathway alone is sufficient as maintenance therapy in xenotransplantation
Initial evidence that blockade of the CD40/CD154 costimulation pathway alone is sufficient as maintenance therapy in xenotransplantation
Early View LETTER TO THE EDITOR David K.C. Cooper, Corresponding Author ...
Genetically engineered pig kidney transplantation in a brain‐dead human subject
Genetically engineered pig kidney transplantation in a brain‐dead human subject
Abstract In September 2021, a kidney (with donor-specific thymic tissue) from an α1, 3-galactosyltransferase gene-kn...
Scientific and psychosocial ethical considerations for initial clinical trials of kidney xenotransplantation
Scientific and psychosocial ethical considerations for initial clinical trials of kidney xenotransplantation
Abstract The initial clinical trials of pig solid organ xenotransplantation (XTx) are drawing closer and could begin in th...
Development and characterization of Gal KO porcine bone marrow‐derived mesenchymal stem cells
Development and characterization of Gal KO porcine bone marrow‐derived mesenchymal stem cells
Abstract Background We demonstrated that neonatal porcine bone marrow-derived mesenchymal stem cell (npBM-MSCs) could impr...
Humanized von Willebrand factor reduces platelet sequestration in ex vivo and in vivo xenotransplant models
Humanized von Willebrand factor reduces platelet sequestration in ex vivo and in vivo xenotransplant models
Abstract The transplantation of organs across species offers the potential to solve the shortage of human organs. While ac...
Histopathology of pig kidney grafts with/without expression of the carbohydrate Neu5Gc in immunosuppressed baboons
Histopathology of pig kidney grafts with/without expression of the carbohydrate Neu5Gc in immunosuppressed baboons
Abstract Introduction Pigs deficient in three glycosyltransferase enzymes (triple-knockout [TKO] pigs, that is, not expres...
Updateon xenotransplantation for May/June 2021
Updateon xenotransplantation for May/June 2021
Corresponding Author Centre for Transplant & Renal Research, Westmead Insti...
Porcine‐derived medical therapies for SARS‐CoV‐2: Traversing Muslim bioethical concerns and assuring equity
Porcine‐derived medical therapies for SARS‐CoV‐2: Traversing Muslim bioethical concerns and assuring equity
Corresponding Author Initiative on Islam and Medicine, Brookfield, Wisconsin, U...
Expression of human CD47 in pig glomeruli prevents proteinuria and prolongs graft survival following pig‐to‐baboon xenotransplantation
Expression of human CD47 in pig glomeruli prevents proteinuria and prolongs graft survival following pig‐to‐baboon xenotransplantation
Abstract Background Nephrotic syndrome is a common complication of pig-to-baboon kidney xenotransplantation (KXTx) that ad...
Sensitive detection systems for infectious agents in xenotransplantation*
Sensitive detection systems for infectious agents in xenotransplantation*
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganism...
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