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Prognostic significance of platelet-to-lymphocyte ratio (PLR) in patients with breast cancer treated with neoadjuvant chemotherapy: a meta-analysis
Prognostic significance of platelet-to-lymphocyte ratio (PLR) in patients with breast cancer treated with neoadjuvant chemotherapy: a meta-analysis
IntroductionBreast cancer (BC) is the most frequently diagnosed malignant neoplasm in women worldwide.1 Patients with BC i...
Factors associated with continuation of hormonal contraceptives among married women of reproductive age in Gilgit, Pakistan: a community-based case-control study
Factors associated with continuation of hormonal contraceptives among married women of reproductive age in Gilgit, Pakistan: a community-based case-control study
STRENGTHS AND LIMITATIONS OF THIS STUDYThe case-to-control ratio was kept at 1:2, which enhances the likelihood that our f...
Assessment of health literacy in patients with polycystic ovary syndrome and its relationship with health behaviours: a cross-sectional study
Assessment of health literacy in patients with polycystic ovary syndrome and its relationship with health behaviours: a cross-sectional study
Strengths and limitations of this studyThis study is the first to explore the relationship between health literacy and hea...
Epidemiological transition: a historical analysis of immigration patterns by country of origin (1861-1986) related to circulatory system diseases and all-cause mortality in twentieth-century Australia
Epidemiological transition: a historical analysis of immigration patterns by country of origin (1861-1986) related to circulatory system diseases and all-cause mortality in twentieth-century Australia
STRENGTHS AND LIMITATIONS OF THIS STUDYAn original analysis employing census data and immigration patterns to reinterpret ...
Paediatric hospitalisation related to medications administration errors of non-opioid analgesics, antipyretics and antirheumatics in England and Wales: a longitudinal ecological study
Paediatric hospitalisation related to medications administration errors of non-opioid analgesics, antipyretics and antirheumatics in England and Wales: a longitudinal ecological study
STRENGTHS AND LIMITATIONS OF THIS STUDYThis study investigated the hospitalisation patterns associated with medication adm...
Association between preterm delivery and subsequent maternal risk of hypertension and type 2 diabetes mellitus in a UK population-based retrospective cohort study
Association between preterm delivery and subsequent maternal risk of hypertension and type 2 diabetes mellitus in a UK population-based retrospective cohort study
Main findingsIn this population-based retrospective matched open cohort study, we aimed to explore whether preterm deliver...
COVID-19 anxiety and related factors amid adjusted epidemic prevention policies: a cross-sectional study on patients with late-life depression in China
COVID-19 anxiety and related factors amid adjusted epidemic prevention policies: a cross-sectional study on patients with late-life depression in China
STRENGTHS AND LIMITATIONS OF THIS STUDYThis cross-sectional study assessed COVID-19 anxiety levels in patients with late-l...
Impact of a capacity-building intervention on views and perceptions of healthcare providers towards the provision of adolescent sexual and reproductive health services in southeast Nigeria: a cross-sectional qualitative study
Impact of a capacity-building intervention on views and perceptions of healthcare providers towards the provision of adolescent sexual and reproductive health services in southeast Nigeria: a cross-sectional qualitative study
STRENGTHS AND LIMITATIONS OF THIS STUDYThe team of researchers in collaboration with the local stakeholders co-created and...
Experiences of adolescents using sexual health services on Reunion Island: protocol for a qualitative phenomenological study
Experiences of adolescents using sexual health services on Reunion Island: protocol for a qualitative phenomenological study
IntroductionAdolescence and early adulthood are often critical periods of sexual development.1 The considerable physical, ...
Early monitoring of intravenous thrombolysis in acute ischaemic stroke using wearable intelligent vital sign devices: protocol for a prospective, multicentre, observational registry cohort study
Early monitoring of intravenous thrombolysis in acute ischaemic stroke using wearable intelligent vital sign devices: protocol for a prospective, multicentre, observational registry cohort study
IntroductionAccording to the 2019 Global Burden of Disease study, stroke is the second leading cause of death and the thir...
Non-pharmacological interventions for patients with psoriasis: a scoping review
Non-pharmacological interventions for patients with psoriasis: a scoping review
STRENGTHS AND LIMITATIONS OF THIS STUDYThis review included studies conducted in different settings, which emphasised the ...
Geospatial analysis of the hospitalisation rate of patients with rheumatoid arthritis in Hunan: a cross-sectional Chinese study
Geospatial analysis of the hospitalisation rate of patients with rheumatoid arthritis in Hunan: a cross-sectional Chinese study
IntroductionRheumatoid arthritis (RA) is an autoimmune disease characterised by abnormal synovial hyperplasia and progress...
Work-related stress and associated factors among health professionals working in Ambo town public health facilities, West Shoa Zone, Ethiopia, 2021: a cross-sectional study
Work-related stress and associated factors among health professionals working in Ambo town public health facilities, West Shoa Zone, Ethiopia, 2021: a cross-sectional study
STRENGTHS AND LIMITATIONS OF THIS STUDYThe study used the gold standard (simple random) sampling technique.It is not gener...
Key CT markers for predicting haemorrhagic transformation after ischaemic stroke: a prospective cohort study in China
Key CT markers for predicting haemorrhagic transformation after ischaemic stroke: a prospective cohort study in China
STRENGTHS AND LIMITATIONS OF THIS STUDYWe collected a panel of imaging markers on multimodal CT and systematically analyse...
Solutions to Enhance Health with Alternative Treatments (SEHAT) protocol: a double-blinded randomised controlled trial for gut microbiota-targeted treatment of severe acute malnutrition using rice bran in ready-to-use therapeutic foods in Indonesia
Solutions to Enhance Health with Alternative Treatments (SEHAT) protocol: a double-blinded randomised controlled trial for gut microbiota-targeted treatment of severe acute malnutrition using rice bran in ready-to-use therapeutic foods in Indonesia
IntroductionSevere acute malnutrition (SAM) remains a leading global contributor to early childhood morbidity and mortalit...
IC3 protocol: a longitudinal observational study of cognition after stroke using novel digital health technology
IC3 protocol: a longitudinal observational study of cognition after stroke using novel digital health technology
STRENGTHS AND LIMITATIONS OF THIS STUDYA major methodological strength of the study involves the development of the first ...
Association of serum potassium level with dietary potassium intake in Chinese older adults: a multicentre, cross-sectional survey
Association of serum potassium level with dietary potassium intake in Chinese older adults: a multicentre, cross-sectional survey
Strengths and limitations of this studyThis is the first study in the general population on the study interest, using a we...
School health professionals understanding of culture: a scoping review protocol
School health professionals understanding of culture: a scoping review protocol
Global trends suggest that more people have migrated than ever before. In 2020, about 281 million people were internationa...
Policy-makers conception of patient non-attendance fees in specialist healthcare: a qualitative document analysis
Policy-makers conception of patient non-attendance fees in specialist healthcare: a qualitative document analysis
BackgroundPatients missing their appointments without giving notice burden healthcare systems because unplanned non-attend...
Cross-sectional analyses of online appointment booking and repeat prescription ordering user characteristics in general practices of England in the years 2018-2020
Cross-sectional analyses of online appointment booking and repeat prescription ordering user characteristics in general practices of England in the years 2018-2020
BackgroundOnline services such as online appointment booking or repeat prescription ordering are offered in 99.7% of Gener...
Impact of strategies to mitigate misinformation in diverse settings and populations: a protocol for a living evidence synthesis
Impact of strategies to mitigate misinformation in diverse settings and populations: a protocol for a living evidence synthesis
IntroductionIncreasing digitalisation and use of social media is a two-edged sword.1 It creates opportunities to rapidly c...
Evaluating the impact on health outcomes of an event that resulted in a delay in contact tracing of COVID-19 cases in England, September 2020: an observational study
Evaluating the impact on health outcomes of an event that resulted in a delay in contact tracing of COVID-19 cases in England, September 2020: an observational study
IntroductionAs of October 2023, there have been over 22 million cases and 200 000 deaths from COVID-19 reported in the UK....
Voice of incarcerated male youths in Malawis semi-urban prisons: a qualitative study
Voice of incarcerated male youths in Malawis semi-urban prisons: a qualitative study
IntroductionGlobally, the number of incarcerated people continues to rise annually, including in sub-Saharan Africa (SSA)....
Nursing support for breathlessness in patients with cancer: a scoping review
Nursing support for breathlessness in patients with cancer: a scoping review
STRENGTHS AND LIMITATIONS OF THIS STUDYThis is the first scoping review on nursing support for breathlessness in patients ...
Prognostic prediction models for oropharyngeal squamous cell carcinoma (OPSCC): a protocol for systematic review, critical appraisal and meta-analysis
Prognostic prediction models for oropharyngeal squamous cell carcinoma (OPSCC): a protocol for systematic review, critical appraisal and meta-analysis
STRENGTHS AND LIMITATIONS OF THIS STUDYThis study will provide the comprehensive evidence on existing prognostic predictio...
Epidemiology of emergency and elective caesarean section and its association with early neonatal mortality in sub-Saharan African countries
Epidemiology of emergency and elective caesarean section and its association with early neonatal mortality in sub-Saharan African countries
STRENGTHS AND LIMITATIONS OF THIS STUDYThis study analysed weighted nationally representative Demographic and Health Surve...
Factors influencing choice of b/ts DMARDs in managing inflammatory arthritis from a patient perspective: a systematic review of global evidence and a patient-based survey from Hong Kong
Factors influencing choice of b/ts DMARDs in managing inflammatory arthritis from a patient perspective: a systematic review of global evidence and a patient-based survey from Hong Kong
Systematic review of global evidenceOverviewTwo thousand two hundred and sixty-one studies were searched out of four datab...
Transforming growth factor-{beta} and matrix metalloproteinases as potential biomarkers of fibrotic lesions induced by tuberculosis: a systematic review and meta-analysis
Transforming growth factor-{beta} and matrix metalloproteinases as potential biomarkers of fibrotic lesions induced by tuberculosis: a systematic review and meta-analysis
STRENGTHS AND LIMITATIONS OF THIS STUDYThere is no limitation to the time frame used in the literature search of this stud...
Province-level distribution and drivers of infant mortality in mainland China: a Geodetector-based analysis of data from 2020
Province-level distribution and drivers of infant mortality in mainland China: a Geodetector-based analysis of data from 2020
STRENGTHS AND LIMITATIONS OF THIS STUDYThis study used Geodetector to analyse drivers of infant mortality rate (IMR), and ...
Establishment of prediction models to predict survival among patients with cervical cancer based on socioeconomic factors: a retrospective cohort study based on the SEER Database
Establishment of prediction models to predict survival among patients with cervical cancer based on socioeconomic factors: a retrospective cohort study based on the SEER Database
STRENGTHS AND LIMITATIONS OF THIS STUDYA large public database was used.A Cox proportional hazards model was applied.To co...
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