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Spinal Muscular Atrophy: Advances in Diagnosis, Treatment, and Emerging Therapies
Spinal Muscular Atrophy: Advances in Diagnosis, Treatment, and Emerging Therapies
This review summarizes recent advances in the diagnosis and treatment of spinal muscular atrophy (SMA), with emphasis on n...
Treatment Decision-Making in Distal-Medium Vessel Occlusions: A Case-Based Perspective Review
Treatment Decision-Making in Distal-Medium Vessel Occlusions: A Case-Based Perspective Review
Medium and distal vessel occlusions (DMVOs) account for approximately one third of all acute ischemic strokes, yet their o...
The Use of AI in Neuroimaging-guided Decision Making in Acute Ischemic Stroke
The Use of AI in Neuroimaging-guided Decision Making in Acute Ischemic Stroke
Artificial intelligence (AI) is increasingly being integrated into neuroimaging workflows for the evaluation of acute isch...
Intraglandular Botulinum Toxin Injection for Sialorrhea in the Neurologic Intensive Care Unit
Intraglandular Botulinum Toxin Injection for Sialorrhea in the Neurologic Intensive Care Unit
Sialorrhea is a complication of several neurological disorders often encountered in the neurological intensive care unit (...
Visual Impairment and Driving in Older Adults: A Narrative Review
Visual Impairment and Driving in Older Adults: A Narrative Review
This narrative review synthesizes current evidence on the relationship between visual impairment and driving safety in old...
Repositioning Orexin in Sleep Medicine: From Wake Promotion to Sleep-State Control. A Treatment-Oriented Narrative Review
Repositioning Orexin in Sleep Medicine: From Wake Promotion to Sleep-State Control. A Treatment-Oriented Narrative Review
This review repositions orexin/hypocretin biology within sleep medicine from a primarily wake-promoting framework toward a...
Targeted Treatments for Genetic Epilepsies, Part 1: Channelopathies
Targeted Treatments for Genetic Epilepsies, Part 1: Channelopathies
Genetic diagnoses increasingly guide epilepsy care by informing prognosis, treatment selection, comorbidity management, an...
Artificial Intelligence for Ocular Image Interpretation: From Screening to Clinical Decision Assistance
Artificial Intelligence for Ocular Image Interpretation: From Screening to Clinical Decision Assistance
This review presents an updated overview of the most recent innovations in the use of artificial intelligence (AI) for the...
Restless Legs Syndrome and Mental Health Disturbances: Clinical Implications and Current Treatment Options
Restless Legs Syndrome and Mental Health Disturbances: Clinical Implications and Current Treatment Options
Restless legs syndrome (RLS) is usually framed as a sleep-related movement disorder, but its clinical burden often depends...
End-of-life and Palliative Care in Dementia: An Overview for Clinicians
End-of-life and Palliative Care in Dementia: An Overview for Clinicians
As the population ages, dementia has become a major cause of morbidity and mortality, utilizing palliative care services a...
Primer on Optical Coherence Tomography for the Neurologist
Primer on Optical Coherence Tomography for the Neurologist
This review describes applications of optical coherence tomography (OCT) in the diagnosis, follow-up, and surveillance of ...
Transport of the Neurocritical Care Patient
Transport of the Neurocritical Care Patient
This review aims to summarize the special considerations and gaps in the literature to inform evidence- based practices fo...
Effectiveness and Safety of Edavarone and Dexborneol in Acute Ischemic Stroke: A Systematic Review
Effectiveness and Safety of Edavarone and Dexborneol in Acute Ischemic Stroke: A Systematic Review
Edaravone Dexborneol, a novel neuroprotective agent that combines antioxidant and anti-inflammatory properties, h...
Sleep Neurophysiology and Psychiatric Disorders: a Transdiagnostic Framework for Mechanistic and Therapeutic Insight
Sleep Neurophysiology and Psychiatric Disorders: a Transdiagnostic Framework for Mechanistic and Therapeutic Insight
This narrative review synthesises emerging evidence on the neurophysiological underpinnings of sleep disturbances across p...
Prourokinase in Acute Ischemic Stroke: A Review of Current Evidence
Prourokinase in Acute Ischemic Stroke: A Review of Current Evidence
Stroke is one of the leading causes of long-term morbidity and mortality worldwide. The advent of intravenous thrombolysis...
Update on Management in Patients with Vertebrobasilar Dolichoectasia
Update on Management in Patients with Vertebrobasilar Dolichoectasia
Vertebrobasilar dolichoectasia (VBD) is a vascular pathology characterized by elongation, dilation, and/or tortuosity of t...
Dietary Therapy in the Management of Epilepsy
Dietary Therapy in the Management of Epilepsy
Ketogenic diet therapies are a major, nonpharmacologic method of treating epilepsy, typically when highly refractory. This...
Management of Obstructive Sleep Apnea in Epilepsy
Management of Obstructive Sleep Apnea in Epilepsy
This manuscript presents a broad overview of the implications of obstructive sleep apnea (OSA) co-occurring with epilepsy....
Treatment Considerations in Tumor-Related Epilepsy
Treatment Considerations in Tumor-Related Epilepsy
Tumor-related epilepsy (TRE) is among the most common and disabling complications of brain tumors, affecting approximately...
Laser Interstitial Thermal Therapy for Epilepsy
Laser Interstitial Thermal Therapy for Epilepsy
Magnetic resonance imaging-guided laser interstitial thermal therapy (LITT) has emerged as a minimally invasive alternativ...
Update on Treatment of Orbital Venous-Lymphatic Malformations
Update on Treatment of Orbital Venous-Lymphatic Malformations
Venous-lymphatic malformations of the orbit are congenital, low-flow vascular anomalies composed of mixed venous and lymph...
The Impacts of the Covid-19 Pandemic on Cerebral Infarction Treatment: Challenges and Opportunities
The Impacts of the Covid-19 Pandemic on Cerebral Infarction Treatment: Challenges and Opportunities
This paper summarizes recent literature on the pandemic's effects on IS treatment. The literature is searched in popul...
Epilepsy as a Wilding of Sleep
Epilepsy as a Wilding of Sleep
To review the mutual links of sleep and epilepsy. It is supported in several ways that epilepsy is ‘born’ in s...
Role of Gut Microbiome in Depression
Role of Gut Microbiome in Depression
The beneficial microbes or probiotics replace the hard treatment patterns in diverse arena. In the present review how&...
Tau in Multiple Sclerosis: A Review of Therapeutic Potential
Tau in Multiple Sclerosis: A Review of Therapeutic Potential
Multiple Sclerosis (MS) is a chronic inflammatory neurological disorder affecting over 2.8 million people worldwide. It is...
Update on Stroke Prevention and Treatment in Patients with Antiphospholipid Antibody Syndrome
Update on Stroke Prevention and Treatment in Patients with Antiphospholipid Antibody Syndrome
Antiphospholipid antibody syndrome (APS) is an autoimmune disorder marked by sustained presence of antiphospholipid antibo...