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Substantial skeletal muscle loss occurs during only 5 days of disuse
Abstract Aim The impact of disuse on the loss of skeletal muscle mass and strength has been well documented. Given that mo...
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Muscle volume is a major determinant of joint torque in humans
Muscle force (MF) is linearly related to physiological cross-sectional area (CSA), which is obtained from muscle volume (M...
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Electroporation: theory and methods, perspectives for drug delivery, gene therapy and research
Abstract Electroporation designates the use of short high-voltage pulses to overcome the barrier of the cell membrane. By ...
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Effects of dietary nitrate on oxygen cost during exercise
Abstract Aim: Nitric oxide (NO), synthesized from l-arginine by NO synthases, plays a role in adaptation to physical exer...
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Ground reaction forces at different speeds of human walking and running
In this study the variation in ground reaction force parameters was investigated with respect to adaptations to speed and ...
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Diet, Muscle Glycogen and Physical Performance
Abstract The muscle glycogen content of the quadriceps femoris muscle was determined in 9 healthy subjects with the aid of...
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LKB1 and AMP‐activated protein kinase control of mTOR signalling and growth
Abstract The AMP-activated serine/threonine protein kinase (AMPK) is a sensor of cellular energy status found in all eukar...
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Endothelial dysfunction and vascular disease
Abstract The endothelium can evoke relaxations (dilatations) of the underlying vascular smooth muscle, by releasing vasodi...
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Measurement of skeletal muscle radiation attenuation and basis of its biological variation
Abstract Skeletal muscle contains intramyocellular lipid droplets within the cytoplasm of myocytes as well as intermuscula...
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Skin temperature: its role in thermoregulation
Abstract This review analyses whether skin temperature represents ambient temperature and serves as a feedforward signal f...
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Architectural, functional and molecular responses to concentric and eccentric loading in human skeletal muscle
Abstract Aim We investigated architectural, functional and molecular responses of human skeletal muscle to concentric (CON...
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The neurovascular unit – concept review
Abstract The cerebral hyperaemia is one of the fundamental mechanisms for the central nervous system homeostasis. Due also...
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Sex differences in human fatigability: mechanisms and insight to physiological responses
Abstract Sex-related differences in physiology and anatomy are responsible for profound differences in neuromuscular perfo...
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The role of serotonin and its receptors in activation of immune responses and inflammation
Abstract Serotonin or 5-hydroxytryptamine (5-HT) is a neurotransmitter and hormone that contributes to the regulation of v...
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Vascular smooth muscle cell in atherosclerosis
Abstract Vascular smooth muscle cells (VSMCs) exhibit phenotypic and functional plasticity in order to respond to vascular...
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Biological and physiological role of reactive oxygen species – the good, the bad and the ugly
Abstract Reactive oxygen species (ROS) are chemically reactive molecules that are naturally produced within biological sys...
Acta Physiologica
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Endothelial dysfunction and vascular disease – a 30th anniversary update
Abstract The endothelium can evoke relaxations of the underlying vascular smooth muscle, by releasing vasodilator substanc...
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MicroRNAs in metabolism
Abstract MicroRNAs (miRNAs) have within the past decade emerged as key regulators of metabolic homoeostasis. Major tissues...
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Effects of shear stress on endothelial cells: go with the flow
Abstract Haemodynamic forces influence the functional properties of vascular endothelium. Endothelial cells (ECs) have a v...
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Neuroinfection may contribute to pathophysiology and clinical manifestations of COVID‐19
The new coronavirus, classified as severe acute respiratory syndrome (SARS)-CoV-2 that emerged in Hubei province in China,...
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Mind the gap: mechanisms regulating the endothelial barrier
Abstract The endothelial barrier consists of intercellular contacts localized in the cleft between endothelial cells, whic...
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